Cyclin-dependent kinase 2
Kinase structure
Kinase:CDK2
Family:CDK
Group:CMGC
Species:HUMAN
IUPHAR/BPS ID:1973
PDB:5OO0
sc-PDB:
KIDFamMap:Search
Release date:2018-03-14
PubMed: 29480525
Chain:A
(Alternate) Model:C
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The orthosteric binding pocket


More entries for 5OO0
5OO0Alternative model: AChain: A


Structural information
DFG conformation:in
αC-helix conformation:out
G-rich loop angle (distance):52.3° (14.9Å)
G-rich loop rotation:65.7°
Quality Score:8.7
Resolution:1.6 Å
Missing Residues:0
Missing Atoms:13
Ligand binding mode
Waters
Cluster
I3
I4
I5
I6
I7
I8
Ligand
No
No
No
No
No
No
Protein
No
No
Yes
No
No
Yes

Allosteric Ligand
Allosteric ligand:9YZ
2D structure of the allostericligand
Pocket alignment
Uniprot sequence:EKIGEGTYGVVYKVALKKITAIREISLLKELNPNIVKLLDVYLVFEFLH-QDLKKFMDAFCHSHRVLHRDLKPQNLLILADFGLA
Sequence structure:EKIGEGTYGVVYKVALKKITAIREISLLKELNPNIVKLLDVYLVFEFLH_QDLKKFMDAFCHSHRVLHRDLKPQNLLILADFGLA