SRC proto-oncogene, non-receptor tyrosine kinase
Kinase structure
Kinase:SRC
Family:Src
Group:TK
Species:HUMAN
IUPHAR/BPS ID:2206
PDB:1YI6
sc-PDB:
KIDFamMap:Search
Release date:2006-05-02
Chain:B
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The orthosteric binding pocket


More entries for 1YI6
1YI6Chain: A


Structural information
DFG conformation:in
αC-helix conformation:in
G-rich loop angle (distance):62.4° (18.7Å)
G-rich loop rotation:47.6°
Quality Score:8
Resolution:2 Å
Missing Residues:0
Missing Atoms:0
Ligand binding mode
Waters
Cluster
I1
I5
I6
I11
Ligand
No
No
No
No
Protein
Yes
Yes
No
Yes

Pocket alignment
Uniprot sequence:VKLGQGCFGEVWMVAIKTLAFLQEAQVMKKLREKLVQLYAVYIVTEYMSKGSLLDFLKGYVERMNYVHRDLRAANILVVADFGLA
Sequence structure:VKLGQGCFGEVWMVAIKTLAFLQEAQVMKKLREKLVQLYAVYIVTEYMSKGSLLDFLKGYVERMNYVHRDLRAANILVVADFGLA