PDB-code
Browse kinase entries (page 103 of 282)
First 99 100 101 PreviousLast107 106 105 Next| # | Kinase | Family | Group | PDB | Chain | (Alternate) Model | Orthosteric ligand | Organism | Details | File |
|---|---|---|---|---|---|---|---|---|---|---|
 | EGFR | EGFR | TK | 5gtz | A | B | n-[5-[[5-chloranyl-4-[(2-propan-2-ylsulfonylphenyl)amino]pyrimidin-2-yl]amino]-2-(4-ethylpiperazin-1-yl)-4-methoxy-phenyl]prop-2-enamide | Human | Show |  |
| EGFR | EGFR | TK | 5hcx | A | ~{n}-[2-(1-cyclopropylsulfonylpyrazol-4-yl)pyrimidin-4-yl]-2-methyl-1-propan-2-yl-imidazo[4,5-c]pyridin-6-amine | Human | Show | | |
| EGFR | EGFR | TK | 5hcy | A | 6-[[2-(1-cyclopropylsulfonylpyrazol-4-yl)pyrimidin-4-yl]amino]-~{n}-(oxan-4-yl)-1-propan-2-yl-pyrrolo[3,2-c]pyridine-3-carboxamide | Human | Show | | |
| EGFR | EGFR | TK | 5hcz | A | 2-[1-[1-[(2~{s})-butan-2-yl]-6-[[2-(1-cyclopropylsulfonylpyrazol-4-yl)pyrimidin-4-yl]amino]pyrazolo[4,3-c]pyridin-3-yl]azetidin-3-yl]propan-2-ol | Human | Show | | |
| EGFR | EGFR | TK | 5hg5 | A | A | n-{3-[(2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}-7h-pyrrolo[2,3-d]pyrimidin-4-yl)oxy]phenyl}propanamide | Human | Show | |
| EGFR | EGFR | TK | 5hg5 | A | B | n-{3-[(2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}-7h-pyrrolo[2,3-d]pyrimidin-4-yl)oxy]phenyl}propanamide | Human | Show | |
| EGFR | EGFR | TK | 5hg7 | A | 1-{(3r,4r)-3-[({5-chloro-2-[(1-methyl-1h-pyrazol-4-yl)amino]-7h-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)methyl]-4-methoxypyrrolidin-1-yl}propan-1-one | Human | Show | | |
| EGFR | EGFR | TK | 5hg8 | A | A | n-[3-({2-[(1-methyl-1h-pyrazol-4-yl)amino]-7h-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]propanamide | Human | Show | |
| EGFR | EGFR | TK | 5hg8 | A | B | n-[3-({2-[(1-methyl-1h-pyrazol-4-yl)amino]-7h-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]propanamide | Human | Show | |
| EGFR | EGFR | TK | 5hg9 | A | A | 1-[(3r,4r)-3-[({2-[(1-methyl-1h-pyrazol-4-yl)amino]-7h-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)methyl]-4-(trifluoromethyl)pyrrolidin-1-yl]propan-1-one | Human | Show | |
| EGFR | EGFR | TK | 5hg9 | A | B | 1-[(3r,4r)-3-[({2-[(1-methyl-1h-pyrazol-4-yl)amino]-7h-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)methyl]-4-(trifluoromethyl)pyrrolidin-1-yl]propan-1-one | Human | Show | |
| EGFR | EGFR | TK | 5hib | A | n-tert-butyl-5-{[(1-methyl-1h-pyrazol-5-yl)sulfonyl]amino}pyrazolo[1,5-a]pyrimidine-3-carboxamide | Human | Show | | |
| EGFR | EGFR | TK | 5hic | A | n-{2-[1-(cyclopropylsulfonyl)-1h-pyrazol-4-yl]pyrimidin-4-yl}-1-(propan-2-yl)-1h-imidazo[4,5-c]pyridin-6-amine | Human | Show | | |
| EGFR | EGFR | TK | 5j9y | A | A | (r)-1-(3-(4-amino-3-(naphthalen-1-yl)-1h-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)prop-2-en-1-one | Human | Show | |
| EGFR | EGFR | TK | 5j9y | A | B | (r)-1-(3-(4-amino-3-(naphthalen-1-yl)-1h-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)prop-2-en-1-one | Human | Show | |
| EGFR | EGFR | TK | 5j9z | A | (r)-1-(3-(4-amino-3-(1-methyl-1h-indol-3-yl)-1h-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)prop-2-en-1-one | Human | Show | | |
| EGFR | EGFR | TK | 5jeb | A | 3-(furan-2-yl)-n-[5-(furan-2-yl)-2-methoxyphenyl]-1h-pyrazolo[3,4-d]pyrimidin-4-amine | Human | Show | | |
| EGFR | EGFR | TK | 5u8l | A | A | 4-[(4-{4-[(3-cyclopropyl-1h-pyrazol-5-yl)amino]-6-[(prop-2-yn-1-yl)carbamoyl]pyrimidin-2-yl}piperazin-1-yl)methyl]benzene-1-sulfonyl fluoride | Human | Show | |
| EGFR | EGFR | TK | 5u8l | A | B | 4-[(4-{4-[(3-cyclopropyl-1h-pyrazol-5-yl)amino]-6-[(prop-2-yn-1-yl)carbamoyl]pyrimidin-2-yl}piperazin-1-yl)methyl]benzene-1-sulfonyl fluoride | Human | Show | |
| EGFR | EGFR | TK | 5ug8 | A | A | n-[(3r,4r)-4-fluoro-1-{6-[(1-methyl-1h-pyrazol-4-yl)amino]-9-(propan-2-yl)-9h-purin-2-yl}pyrrolidin-3-yl]propanamide | Human | Show | |
| EGFR | EGFR | TK | 5ug8 | A | B | n-[(3r,4r)-4-fluoro-1-{6-[(1-methyl-1h-pyrazol-4-yl)amino]-9-(propan-2-yl)-9h-purin-2-yl}pyrrolidin-3-yl]propanamide | Human | Show | |
| EGFR | EGFR | TK | 5ug9 | A | A | n-[(3r,4r)-4-fluoro-1-{6-[(3-methoxy-1-methyl-1h-pyrazol-4-yl)amino]-9-(propan-2-yl)-9h-purin-2-yl}pyrrolidin-3-yl]propanamide | Human | Show | |
| EGFR | EGFR | TK | 5ug9 | A | B | n-[(3r,4r)-4-fluoro-1-{6-[(3-methoxy-1-methyl-1h-pyrazol-4-yl)amino]-9-(propan-2-yl)-9h-purin-2-yl}pyrrolidin-3-yl]propanamide | Human | Show | |
| EGFR | EGFR | TK | 5uga | A | A | 4-(4-{[2-{[(3s)-1-acetylpyrrolidin-3-yl]amino}-9-(propan-2-yl)-9h-purin-6-yl]amino}phenyl)-1-methylpiperazin-1-ium | Human | Show | |
| EGFR | EGFR | TK | 5uga | A | B | 4-(4-{[2-{[(3s)-1-acetylpyrrolidin-3-yl]amino}-9-(propan-2-yl)-9h-purin-6-yl]amino}phenyl)-1-methylpiperazin-1-ium | Human | Show | |
| EGFR | EGFR | TK | 5ugb | A | 4-(4-{[2-{[(3s)-1-acetylpyrrolidin-3-yl]amino}-9-(propan-2-yl)-9h-purin-6-yl]amino}phenyl)-1-methylpiperazin-1-ium | Human | Show | | |
| EGFR | EGFR | TK | 5ugc | A | A | n-[(3r,4r)-4-fluoro-1-{6-[(3-methoxy-1-methyl-1h-pyrazol-4-yl)amino]-9-methyl-9h-purin-2-yl}pyrrolidin-3-yl]propanamide | Human | Show | |
| EGFR | EGFR | TK | 5ugc | A | B | n-[(3r,4r)-4-fluoro-1-{6-[(3-methoxy-1-methyl-1h-pyrazol-4-yl)amino]-9-methyl-9h-purin-2-yl}pyrrolidin-3-yl]propanamide | Human | Show | |
| EGFR | EGFR | TK | 5uwd | A | n-(3-{[2-{[4-(4-acetylpiperazin-1-yl)-2-methoxyphenyl]amino}-5-(trifluoromethyl)pyrimidin-4-yl]amino}phenyl)propanamide | Human | Show | | |
| EGFR | EGFR | TK | 5x26 | A | n2-[4-(4-methylpiperazin-1-yl)phenyl]-n8-phenyl-9-propan-2-yl-purine-2,8-diamine | Human | Show | | |
| EGFR | EGFR | TK | 5x27 | A | 9-cyclopentyl-n2-[4-(4-methylpiperazin-1-yl)phenyl]-n8-phenyl-purine-2,8-diamine | Human | Show | | |
| EGFR | EGFR | TK | 5x28 | A | 9-cyclohexyl-n2-[4-(4-methylpiperazin-1-yl)phenyl]-n8-phenyl-purine-2,8-diamine | Human | Show | | |
| EGFR | EGFR | TK | 5x2a | A | A | n2-[4-(4-methylpiperazin-1-yl)phenyl]-n8-phenyl-9-propan-2-yl-purine-2,8-diamine | Human | Show | |
| EGFR | EGFR | TK | 5x2a | A | B | n2-[4-(4-methylpiperazin-1-yl)phenyl]-n8-phenyl-9-propan-2-yl-purine-2,8-diamine | Human | Show | |
| EGFR | EGFR | TK | 5x2a | A | C | n2-[4-(4-methylpiperazin-1-yl)phenyl]-n8-phenyl-9-propan-2-yl-purine-2,8-diamine | Human | Show | |
| EGFR | EGFR | TK | 5x2a | B | A | n2-[4-(4-methylpiperazin-1-yl)phenyl]-n8-phenyl-9-propan-2-yl-purine-2,8-diamine | Human | Show | |
| EGFR | EGFR | TK | 5x2a | B | B | n2-[4-(4-methylpiperazin-1-yl)phenyl]-n8-phenyl-9-propan-2-yl-purine-2,8-diamine | Human | Show | |
| EGFR | EGFR | TK | 5x2a | B | C | n2-[4-(4-methylpiperazin-1-yl)phenyl]-n8-phenyl-9-propan-2-yl-purine-2,8-diamine | Human | Show | |
| EGFR | EGFR | TK | 5x2a | C | A | n2-[4-(4-methylpiperazin-1-yl)phenyl]-n8-phenyl-9-propan-2-yl-purine-2,8-diamine | Human | Show | |
| EGFR | EGFR | TK | 5x2a | C | B | n2-[4-(4-methylpiperazin-1-yl)phenyl]-n8-phenyl-9-propan-2-yl-purine-2,8-diamine | Human | Show | |
| EGFR | EGFR | TK | 5x2a | C | C | n2-[4-(4-methylpiperazin-1-yl)phenyl]-n8-phenyl-9-propan-2-yl-purine-2,8-diamine | Human | Show | |
| EGFR | EGFR | TK | 5x2a | D | A | phosphoaminophosphonic acid-adenylate ester | Human | Show | |
| EGFR | EGFR | TK | 5x2a | D | B | phosphoaminophosphonic acid-adenylate ester | Human | Show | |
| EGFR | EGFR | TK | 5x2a | D | C | phosphoaminophosphonic acid-adenylate ester | Human | Show | |
| EGFR | EGFR | TK | 5x2c | A | A | 9-cyclopentyl-n2-[4-(4-methylpiperazin-1-yl)phenyl]-n8-phenyl-purine-2,8-diamine | Human | Show | |
| EGFR | EGFR | TK | 5x2c | A | B | 9-cyclopentyl-n2-[4-(4-methylpiperazin-1-yl)phenyl]-n8-phenyl-purine-2,8-diamine | Human | Show | |
| EGFR | EGFR | TK | 5x2c | A | C | 9-cyclopentyl-n2-[4-(4-methylpiperazin-1-yl)phenyl]-n8-phenyl-purine-2,8-diamine | Human | Show | |
| EGFR | EGFR | TK | 5x2c | B | A | 9-cyclopentyl-n2-[4-(4-methylpiperazin-1-yl)phenyl]-n8-phenyl-purine-2,8-diamine | Human | Show | |
| EGFR | EGFR | TK | 5x2c | B | B | 9-cyclopentyl-n2-[4-(4-methylpiperazin-1-yl)phenyl]-n8-phenyl-purine-2,8-diamine | Human | Show | |
| EGFR | EGFR | TK | 5x2c | B | C | 9-cyclopentyl-n2-[4-(4-methylpiperazin-1-yl)phenyl]-n8-phenyl-purine-2,8-diamine | Human | Show | |
