PDB-code
Browse kinase entries (page 140 of 282)
First 136 137 138 PreviousLast144 143 142 Next| # | Kinase | Family | Group | PDB | Chain | (Alternate) Model | Orthosteric ligand | Organism | Details | File |
|---|---|---|---|---|---|---|---|---|---|---|
 | IRAK4 | IRAK | TKL | 2oic | C | staurosporine | Human | Show |  | |
| IRAK4 | IRAK | TKL | 2oic | D | staurosporine | Human | Show | | |
| IRAK4 | IRAK | TKL | 2oid | A | phosphoaminophosphonic acid-adenylate ester | Human | Show | | |
| IRAK4 | IRAK | TKL | 2oid | B | phosphoaminophosphonic acid-adenylate ester | Human | Show | | |
| IRAK4 | IRAK | TKL | 2oid | C | phosphoaminophosphonic acid-adenylate ester | Human | Show | | |
| IRAK4 | IRAK | TKL | 2oid | D | phosphoaminophosphonic acid-adenylate ester | Human | Show | | |
| IRAK4 | IRAK | TKL | 4rmz | A | A | 3-nitro-n-[1-phenyl-5-(piperidin-1-ylmethyl)-1h-benzimidazol-2-yl]benzamide | Human | Show | |
| IRAK4 | IRAK | TKL | 4rmz | A | B | 3-nitro-n-[1-phenyl-5-(piperidin-1-ylmethyl)-1h-benzimidazol-2-yl]benzamide | Human | Show | |
| IRAK4 | IRAK | TKL | 4rmz | B | A | 3-nitro-n-[1-phenyl-5-(piperidin-1-ylmethyl)-1h-benzimidazol-2-yl]benzamide | Human | Show | |
| IRAK4 | IRAK | TKL | 4rmz | B | B | 3-nitro-n-[1-phenyl-5-(piperidin-1-ylmethyl)-1h-benzimidazol-2-yl]benzamide | Human | Show | |
| IRAK4 | IRAK | TKL | 4u97 | A | staurosporine | Human | Show | | |
| IRAK4 | IRAK | TKL | 4u97 | B | staurosporine | Human | Show | | |
| IRAK4 | IRAK | TKL | 4u9a | A | staurosporine | Human | Show | | |
| IRAK4 | IRAK | TKL | 4u9a | B | staurosporine | Human | Show | | |
| IRAK4 | IRAK | TKL | 4xs2 | A | (1r,2s,3r,5r)-3-({5-(1,3-benzothiazol-2-yl)-6-chloro-2-[(3-methoxypropyl)amino]pyrimidin-4-yl}amino)-5-(hydroxymethyl)cyclopentane-1,2-diol | Human | Show | | |
| IRAK4 | IRAK | TKL | 4xs2 | B | (1r,2s,3r,5r)-3-({5-(1,3-benzothiazol-2-yl)-6-chloro-2-[(3-methoxypropyl)amino]pyrimidin-4-yl}amino)-5-(hydroxymethyl)cyclopentane-1,2-diol | Human | Show | | |
| IRAK4 | IRAK | TKL | 4xs2 | C | (1r,2s,3r,5r)-3-({5-(1,3-benzothiazol-2-yl)-6-chloro-2-[(3-methoxypropyl)amino]pyrimidin-4-yl}amino)-5-(hydroxymethyl)cyclopentane-1,2-diol | Human | Show | | |
| IRAK4 | IRAK | TKL | 4xs2 | D | (1r,2s,3r,5r)-3-({5-(1,3-benzothiazol-2-yl)-6-chloro-2-[(3-methoxypropyl)amino]pyrimidin-4-yl}amino)-5-(hydroxymethyl)cyclopentane-1,2-diol | Human | Show | | |
| IRAK4 | IRAK | TKL | 4y73 | A | A | 5-{[(1r,2s)-2-aminocyclohexyl]amino}-n-[1-methyl-3-(trifluoromethyl)-1h-pyrazol-4-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide | Human | Show | |
| IRAK4 | IRAK | TKL | 4y73 | A | B | 5-{[(1r,2s)-2-aminocyclohexyl]amino}-n-[1-methyl-3-(trifluoromethyl)-1h-pyrazol-4-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide | Human | Show | |
| IRAK4 | IRAK | TKL | 4y73 | B | A | 5-{[(1r,2s)-2-aminocyclohexyl]amino}-n-[1-methyl-3-(trifluoromethyl)-1h-pyrazol-4-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide | Human | Show | |
| IRAK4 | IRAK | TKL | 4y73 | B | B | 5-{[(1r,2s)-2-aminocyclohexyl]amino}-n-[1-methyl-3-(trifluoromethyl)-1h-pyrazol-4-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide | Human | Show | |
| IRAK4 | IRAK | TKL | 4y73 | C | A | 5-{[(1r,2s)-2-aminocyclohexyl]amino}-n-[1-methyl-3-(trifluoromethyl)-1h-pyrazol-4-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide | Human | Show | |
| IRAK4 | IRAK | TKL | 4y73 | C | B | 5-{[(1r,2s)-2-aminocyclohexyl]amino}-n-[1-methyl-3-(trifluoromethyl)-1h-pyrazol-4-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide | Human | Show | |
| IRAK4 | IRAK | TKL | 4y73 | D | A | 5-{[(1r,2s)-2-aminocyclohexyl]amino}-n-[1-methyl-3-(trifluoromethyl)-1h-pyrazol-4-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide | Human | Show | |
| IRAK4 | IRAK | TKL | 4y73 | D | B | 5-{[(1r,2s)-2-aminocyclohexyl]amino}-n-[1-methyl-3-(trifluoromethyl)-1h-pyrazol-4-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide | Human | Show | |
| IRAK4 | IRAK | TKL | 4yo6 | A | A | n-(3-methyl-1-phenyl-1h-pyrazol-5-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide | Human | Show | |
| IRAK4 | IRAK | TKL | 4yo6 | A | B | n-(3-methyl-1-phenyl-1h-pyrazol-5-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide | Human | Show | |
| IRAK4 | IRAK | TKL | 4yo6 | B | A | n-(3-methyl-1-phenyl-1h-pyrazol-5-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide | Human | Show | |
| IRAK4 | IRAK | TKL | 4yo6 | B | B | n-(3-methyl-1-phenyl-1h-pyrazol-5-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide | Human | Show | |
| IRAK4 | IRAK | TKL | 4yo6 | C | A | n-(3-methyl-1-phenyl-1h-pyrazol-5-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide | Human | Show | |
| IRAK4 | IRAK | TKL | 4yo6 | C | B | n-(3-methyl-1-phenyl-1h-pyrazol-5-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide | Human | Show | |
| IRAK4 | IRAK | TKL | 4yo6 | D | A | n-(3-methyl-1-phenyl-1h-pyrazol-5-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide | Human | Show | |
| IRAK4 | IRAK | TKL | 4yo6 | D | B | n-(3-methyl-1-phenyl-1h-pyrazol-5-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide | Human | Show | |
| IRAK4 | IRAK | TKL | 4yp8 | A | n-{1-(4-cyclopropyl-2-fluorophenyl)-3-[1-(propan-2-yl)piperidin-4-yl]-1h-pyrazol-5-yl}pyrazolo[1,5-a]pyrimidine-3-carboxamide | Human | Show | | |
| IRAK4 | IRAK | TKL | 4yp8 | B | n-{1-(4-cyclopropyl-2-fluorophenyl)-3-[1-(propan-2-yl)piperidin-4-yl]-1h-pyrazol-5-yl}pyrazolo[1,5-a]pyrimidine-3-carboxamide | Human | Show | | |
| IRAK4 | IRAK | TKL | 4yp8 | C | n-{1-(4-cyclopropyl-2-fluorophenyl)-3-[1-(propan-2-yl)piperidin-4-yl]-1h-pyrazol-5-yl}pyrazolo[1,5-a]pyrimidine-3-carboxamide | Human | Show | | |
| IRAK4 | IRAK | TKL | 4yp8 | D | n-{1-(4-cyclopropyl-2-fluorophenyl)-3-[1-(propan-2-yl)piperidin-4-yl]-1h-pyrazol-5-yl}pyrazolo[1,5-a]pyrimidine-3-carboxamide | Human | Show | | |
| IRAK4 | IRAK | TKL | 4ztl | A | A | (1r,2s,3r,5r)-3-{[5-(1,3-benzothiazol-2-yl)-2-(propylamino)pyrimidin-4-yl]amino}-5-(hydroxymethyl)cyclopentane-1,2-diol | Human | Show | |
| IRAK4 | IRAK | TKL | 4ztl | A | B | (1r,2s,3r,5r)-3-{[5-(1,3-benzothiazol-2-yl)-2-(propylamino)pyrimidin-4-yl]amino}-5-(hydroxymethyl)cyclopentane-1,2-diol | Human | Show | |
| IRAK4 | IRAK | TKL | 4ztl | B | A | (1r,2s,3r,5r)-3-{[5-(1,3-benzothiazol-2-yl)-2-(propylamino)pyrimidin-4-yl]amino}-5-(hydroxymethyl)cyclopentane-1,2-diol | Human | Show | |
| IRAK4 | IRAK | TKL | 4ztl | B | B | (1r,2s,3r,5r)-3-{[5-(1,3-benzothiazol-2-yl)-2-(propylamino)pyrimidin-4-yl]amino}-5-(hydroxymethyl)cyclopentane-1,2-diol | Human | Show | |
| IRAK4 | IRAK | TKL | 4ztl | C | A | (1r,2s,3r,5r)-3-{[5-(1,3-benzothiazol-2-yl)-2-(propylamino)pyrimidin-4-yl]amino}-5-(hydroxymethyl)cyclopentane-1,2-diol | Human | Show | |
| IRAK4 | IRAK | TKL | 4ztl | C | B | (1r,2s,3r,5r)-3-{[5-(1,3-benzothiazol-2-yl)-2-(propylamino)pyrimidin-4-yl]amino}-5-(hydroxymethyl)cyclopentane-1,2-diol | Human | Show | |
| IRAK4 | IRAK | TKL | 4ztl | D | A | (1r,2s,3r,5r)-3-{[5-(1,3-benzothiazol-2-yl)-2-(propylamino)pyrimidin-4-yl]amino}-5-(hydroxymethyl)cyclopentane-1,2-diol | Human | Show | |
| IRAK4 | IRAK | TKL | 4ztl | D | B | (1r,2s,3r,5r)-3-{[5-(1,3-benzothiazol-2-yl)-2-(propylamino)pyrimidin-4-yl]amino}-5-(hydroxymethyl)cyclopentane-1,2-diol | Human | Show | |
| IRAK4 | IRAK | TKL | 4ztm | A | 5-(1,3-benzothiazol-2-yl)-2-(cyclopropylamino)-6-{[(1r,2s,3r,4r)-2,3-dihydroxy-4-(hydroxymethyl)cyclopentyl]amino}pyrimidin-4(3h)-one | Human | Show | | |
| IRAK4 | IRAK | TKL | 4ztm | B | 5-(1,3-benzothiazol-2-yl)-2-(cyclopropylamino)-6-{[(1r,2s,3r,4r)-2,3-dihydroxy-4-(hydroxymethyl)cyclopentyl]amino}pyrimidin-4(3h)-one | Human | Show | | |
| IRAK4 | IRAK | TKL | 4ztm | C | 5-(1,3-benzothiazol-2-yl)-2-(cyclopropylamino)-6-{[(1r,2s,3r,4r)-2,3-dihydroxy-4-(hydroxymethyl)cyclopentyl]amino}pyrimidin-4(3h)-one | Human | Show | | |
| IRAK4 | IRAK | TKL | 4ztm | D | 5-(1,3-benzothiazol-2-yl)-2-(cyclopropylamino)-6-{[(1r,2s,3r,4r)-2,3-dihydroxy-4-(hydroxymethyl)cyclopentyl]amino}pyrimidin-4(3h)-one | Human | Show | |
