PDB-code
Browse kinase entries (page 142 of 282)
First 138 139 140 PreviousLast146 145 144 Next| # | Kinase | Family | Group | PDB | Chain | (Alternate) Model | Orthosteric ligand | Organism | Details | File |
|---|---|---|---|---|---|---|---|---|---|---|
 | IRAK4 | IRAK | TKL | 5uiq | D | A | 2-[(propan-2-yl)oxy]benzamide | Human | Show |  |
| IRAK4 | IRAK | TKL | 5uiq | D | B | 2-[(propan-2-yl)oxy]benzamide | Human | Show | |
| IRAK4 | IRAK | TKL | 5uir | A | A | 5-(4-cyanophenyl)-3-[(propan-2-yl)oxy]naphthalene-2-carboxamide | Human | Show | |
| IRAK4 | IRAK | TKL | 5uir | A | B | 5-(4-cyanophenyl)-3-[(propan-2-yl)oxy]naphthalene-2-carboxamide | Human | Show | |
| IRAK4 | IRAK | TKL | 5uir | B | A | 5-(4-cyanophenyl)-3-[(propan-2-yl)oxy]naphthalene-2-carboxamide | Human | Show | |
| IRAK4 | IRAK | TKL | 5uir | B | B | 5-(4-cyanophenyl)-3-[(propan-2-yl)oxy]naphthalene-2-carboxamide | Human | Show | |
| IRAK4 | IRAK | TKL | 5uis | A | A | 4-{[(3r)-piperidin-3-yl]oxy}-6-[(propan-2-yl)oxy]quinoline-7-carboxamide | Human | Show | |
| IRAK4 | IRAK | TKL | 5uis | A | B | 4-{[(3r)-piperidin-3-yl]oxy}-6-[(propan-2-yl)oxy]quinoline-7-carboxamide | Human | Show | |
| IRAK4 | IRAK | TKL | 5uis | B | A | 4-{[(3r)-piperidin-3-yl]oxy}-6-[(propan-2-yl)oxy]quinoline-7-carboxamide | Human | Show | |
| IRAK4 | IRAK | TKL | 5uis | B | B | 4-{[(3r)-piperidin-3-yl]oxy}-6-[(propan-2-yl)oxy]quinoline-7-carboxamide | Human | Show | |
| IRAK4 | IRAK | TKL | 5uis | C | A | 4-{[(3r)-piperidin-3-yl]oxy}-6-[(propan-2-yl)oxy]quinoline-7-carboxamide | Human | Show | |
| IRAK4 | IRAK | TKL | 5uis | C | B | 4-{[(3r)-piperidin-3-yl]oxy}-6-[(propan-2-yl)oxy]quinoline-7-carboxamide | Human | Show | |
| IRAK4 | IRAK | TKL | 5uis | D | A | 4-{[(3r)-piperidin-3-yl]oxy}-6-[(propan-2-yl)oxy]quinoline-7-carboxamide | Human | Show | |
| IRAK4 | IRAK | TKL | 5uis | D | B | 4-{[(3r)-piperidin-3-yl]oxy}-6-[(propan-2-yl)oxy]quinoline-7-carboxamide | Human | Show | |
| IRAK4 | IRAK | TKL | 5uit | A | 1-{[(2s)-5-oxopyrrolidin-2-yl]methoxy}-7-[(propan-2-yl)oxy]isoquinoline-6-carboxamide | Human | Show | | |
| IRAK4 | IRAK | TKL | 5uit | B | 1-{[(2s)-5-oxopyrrolidin-2-yl]methoxy}-7-[(propan-2-yl)oxy]isoquinoline-6-carboxamide | Human | Show | | |
| IRAK4 | IRAK | TKL | 5uiu | A | A | 1-{[(2s,3s,4s)-3-ethyl-4-fluoro-5-oxopyrrolidin-2-yl]methoxy}-7-methoxyisoquinoline-6-carboxamide | Human | Show | |
| IRAK4 | IRAK | TKL | 5uiu | A | B | 1-{[(2s,3s,4s)-3-ethyl-4-fluoro-5-oxopyrrolidin-2-yl]methoxy}-7-methoxyisoquinoline-6-carboxamide | Human | Show | |
| IRAK4 | IRAK | TKL | 5uiu | B | A | 1-{[(2s,3s,4s)-3-ethyl-4-fluoro-5-oxopyrrolidin-2-yl]methoxy}-7-methoxyisoquinoline-6-carboxamide | Human | Show | |
| IRAK4 | IRAK | TKL | 5uiu | B | B | 1-{[(2s,3s,4s)-3-ethyl-4-fluoro-5-oxopyrrolidin-2-yl]methoxy}-7-methoxyisoquinoline-6-carboxamide | Human | Show | |
| IRAK4 | IRAK | TKL | 5w84 | A | 4-(benzylamino)-6-[(2-oxo-2,3-dihydro-1h-indol-5-yl)amino]pyridine-3-carboxamide | Human | Show | | |
| IRAK4 | IRAK | TKL | 5w84 | B | 4-(benzylamino)-6-[(2-oxo-2,3-dihydro-1h-indol-5-yl)amino]pyridine-3-carboxamide | Human | Show | | |
| IRAK4 | IRAK | TKL | 5w85 | A | 6-[(1,3-benzothiazol-6-yl)amino]-4-{[(2s)-1-hydroxy-3-phenylpropan-2-yl]amino}-n-methylpyridine-3-carboxamide | Human | Show | | |
| IRAK4 | IRAK | TKL | 5w85 | B | 6-[(1,3-benzothiazol-6-yl)amino]-4-{[(2s)-1-hydroxy-3-phenylpropan-2-yl]amino}-n-methylpyridine-3-carboxamide | Human | Show | | |
| IRAK4 | IRAK | TKL | 6eg9 | A | A | 3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-n-{4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}benzamide | Human | Show | |
| IRAK4 | IRAK | TKL | 6eg9 | A | B | 3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-n-{4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}benzamide | Human | Show | |
| IRAK4 | IRAK | TKL | 6eg9 | B | A | 3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-n-{4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}benzamide | Human | Show | |
| IRAK4 | IRAK | TKL | 6eg9 | B | B | 3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-n-{4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}benzamide | Human | Show | |
| IRAK4 | IRAK | TKL | 6ega | A | A | 3-{2-[(cyclopropanecarbonyl)amino][1,3]thiazolo[5,4-b]pyridin-5-yl}-n-{4-[(piperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}benzamide | Human | Show | |
| IRAK4 | IRAK | TKL | 6ega | A | B | 3-{2-[(cyclopropanecarbonyl)amino][1,3]thiazolo[5,4-b]pyridin-5-yl}-n-{4-[(piperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}benzamide | Human | Show | |
| IRAK4 | IRAK | TKL | 6ega | B | A | 3-{2-[(cyclopropanecarbonyl)amino][1,3]thiazolo[5,4-b]pyridin-5-yl}-n-{4-[(piperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}benzamide | Human | Show | |
| IRAK4 | IRAK | TKL | 6ega | B | B | 3-{2-[(cyclopropanecarbonyl)amino][1,3]thiazolo[5,4-b]pyridin-5-yl}-n-{4-[(piperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}benzamide | Human | Show | |
| IRAK4 | IRAK | TKL | 6egd | A | A | n-[2-methoxy-4-(morpholin-4-yl)phenyl]-2-(pyridin-3-yl)-1,3-thiazole-5-carboxamide | Human | Show | |
| IRAK4 | IRAK | TKL | 6egd | A | B | n-[2-methoxy-4-(morpholin-4-yl)phenyl]-2-(pyridin-3-yl)-1,3-thiazole-5-carboxamide | Human | Show | |
| IRAK4 | IRAK | TKL | 6egd | D | A | n-[2-methoxy-4-(morpholin-4-yl)phenyl]-2-(pyridin-3-yl)-1,3-thiazole-5-carboxamide | Human | Show | |
| IRAK4 | IRAK | TKL | 6egd | D | B | n-[2-methoxy-4-(morpholin-4-yl)phenyl]-2-(pyridin-3-yl)-1,3-thiazole-5-carboxamide | Human | Show | |
| IRAK4 | IRAK | TKL | 6ege | A | A | n-[2-methoxy-4-(morpholin-4-yl)phenyl]-6-(1h-pyrazol-5-yl)pyridine-2-carboxamide | Human | Show | |
| IRAK4 | IRAK | TKL | 6ege | A | B | n-[2-methoxy-4-(morpholin-4-yl)phenyl]-6-(1h-pyrazol-5-yl)pyridine-2-carboxamide | Human | Show | |
| IRAK4 | IRAK | TKL | 6ege | D | A | n-[2-methoxy-4-(morpholin-4-yl)phenyl]-6-(1h-pyrazol-5-yl)pyridine-2-carboxamide | Human | Show | |
| IRAK4 | IRAK | TKL | 6ege | D | B | n-[2-methoxy-4-(morpholin-4-yl)phenyl]-6-(1h-pyrazol-5-yl)pyridine-2-carboxamide | Human | Show | |
| IRAK4 | IRAK | TKL | 6egf | B | phosphoaminophosphonic acid-adenylate ester | Human | Show | | |
| IRAK4 | IRAK | TKL | 6f3d | A | 4-[4-[[4-(dimethylamino)cyclohexyl]amino]-7~{h}-pyrrolo[2,3-d]pyrimidin-5-yl]cyclohexane-1-carboxamide | Human | Show | | |
| IRAK4 | IRAK | TKL | 6f3d | B | 4-[4-[[4-(dimethylamino)cyclohexyl]amino]-7~{h}-pyrrolo[2,3-d]pyrimidin-5-yl]cyclohexane-1-carboxamide | Human | Show | | |
| IRAK4 | IRAK | TKL | 6f3e | A | 2-[(3~{r})-12-(4-morpholin-4-ylcyclohexyl)oxy-7-thia-9,11-diazatricyclo[6.4.0.0^{2,6}]dodeca-1(8),2(6),9,11-tetraen-3-yl]ethanamide | Human | Show | | |
| IRAK4 | IRAK | TKL | 6f3e | B | 2-[(3~{r})-12-(4-morpholin-4-ylcyclohexyl)oxy-7-thia-9,11-diazatricyclo[6.4.0.0^{2,6}]dodeca-1(8),2(6),9,11-tetraen-3-yl]ethanamide | Human | Show | | |
| IRAK4 | IRAK | TKL | 6f3g | A | ~{n}4,~{n}4-dimethyl-~{n}1-(5-propan-2-ylpyrrolo[3,2-d]pyrimidin-4-yl)cyclohexane-1,4-diamine | Human | Show | | |
| IRAK4 | IRAK | TKL | 6f3g | B | ~{n}4,~{n}4-dimethyl-~{n}1-(5-propan-2-ylpyrrolo[3,2-d]pyrimidin-4-yl)cyclohexane-1,4-diamine | Human | Show | | |
| IRAK4 | IRAK | TKL | 6f3i | A | (3~{r})-3-[4-[[4-(4-ethanoylpiperazin-1-yl)cyclohexyl]amino]pyrrolo[2,1-f][1,2,4]triazin-5-yl]butanamide | Human | Show | | |
| IRAK4 | IRAK | TKL | 6f3i | B | (3~{r})-3-[4-[[4-(4-ethanoylpiperazin-1-yl)cyclohexyl]amino]pyrrolo[2,1-f][1,2,4]triazin-5-yl]butanamide | Human | Show | | |
| IRAK4 | IRAK | TKL | 6lxy | B | n-[(2r)-2-fluoranyl-3-methyl-3-oxidanyl-butyl]-6-[(6-fluoranylpyrazolo[1,5-a]pyrimidin-5-yl)amino]-4-(propan-2-ylamino)pyridine-3-carboxamide | Human | Show | |
