PDB-code
Browse kinase entries (page 145 of 282)
First 141 142 143 PreviousLast149 148 147 Next| # | Kinase | Family | Group | PDB | Chain | (Alternate) Model | Orthosteric ligand | Organism | Details | File |
|---|---|---|---|---|---|---|---|---|---|---|
 | IRAK4 | IRAK | TKL | 8atl | A | A | ~{n}-[6-methoxy-2-(2-morpholin-4-yl-2-oxidanylidene-ethyl)indazol-5-yl]-6-[(1~{r})-2,2,2-tris(fluoranyl)-1-oxidanyl-ethyl]pyridine-2-carboxamide | Human | Show |  |
| IRAK4 | IRAK | TKL | 8atl | A | B | ~{n}-[6-methoxy-2-(2-morpholin-4-yl-2-oxidanylidene-ethyl)indazol-5-yl]-6-[(1~{r})-2,2,2-tris(fluoranyl)-1-oxidanyl-ethyl]pyridine-2-carboxamide | Human | Show | |
| IRAK4 | IRAK | TKL | 8atl | B | A | ~{n}-[6-methoxy-2-(2-morpholin-4-yl-2-oxidanylidene-ethyl)indazol-5-yl]-6-[(1~{r})-2,2,2-tris(fluoranyl)-1-oxidanyl-ethyl]pyridine-2-carboxamide | Human | Show | |
| IRAK4 | IRAK | TKL | 8atl | B | B | ~{n}-[6-methoxy-2-(2-morpholin-4-yl-2-oxidanylidene-ethyl)indazol-5-yl]-6-[(1~{r})-2,2,2-tris(fluoranyl)-1-oxidanyl-ethyl]pyridine-2-carboxamide | Human | Show | |
| IRAK4 | IRAK | TKL | 8atn | A | A | ~{n}-[3-methyl-2-(3-methyl-3-oxidanyl-butyl)-6-(2-oxidanylpropan-2-yl)benzimidazol-5-yl]-6-(trifluoromethyl)pyridine-2-carboxamide | Human | Show | |
| IRAK4 | IRAK | TKL | 8atn | A | B | ~{n}-[3-methyl-2-(3-methyl-3-oxidanyl-butyl)-6-(2-oxidanylpropan-2-yl)benzimidazol-5-yl]-6-(trifluoromethyl)pyridine-2-carboxamide | Human | Show | |
| IRAK4 | IRAK | TKL | 8br5 | A | A | ~{n}-[2,3-dimethyl-6-(1~{h}-pyrazol-5-yl)benzimidazol-5-yl]-6-(trifluoromethyl)pyridine-2-carboxamide | Human | Show | |
| IRAK4 | IRAK | TKL | 8br5 | A | B | ~{n}-[2,3-dimethyl-6-(1~{h}-pyrazol-5-yl)benzimidazol-5-yl]-6-(trifluoromethyl)pyridine-2-carboxamide | Human | Show | |
| IRAK4 | IRAK | TKL | 8br6 | A | A | ~{n}-[6-methoxy-2-(2-methylsulfonylethyl)-1,3-dihydroindazol-5-yl]-6-(2-oxidanylpropan-2-yl)pyridine-2-carboxamide | Human | Show | |
| IRAK4 | IRAK | TKL | 8br6 | A | B | ~{n}-[6-methoxy-2-(2-methylsulfonylethyl)-1,3-dihydroindazol-5-yl]-6-(2-oxidanylpropan-2-yl)pyridine-2-carboxamide | Human | Show | |
| IRAK4 | IRAK | TKL | 8br7 | A | 3-nitro-~{n}-[2-[2-oxidanylidene-2-[4-(phenylcarbonyl)piperazin-1-yl]ethyl]indazol-5-yl]benzamide | Human | Show | | |
| IRAK4 | IRAK | TKL | 8dks | A | A | (1s,2s,3r,4r)-3-({2-[3-(pyrrolidine-1-carbonyl)anilino]thieno[3,2-d]pyrimidin-4-yl}amino)bicyclo[2.2.1]hept-5-ene-2-carboxamide | Human | Show | |
| IRAK4 | IRAK | TKL | 8dks | A | B | (1s,2s,3r,4r)-3-({2-[3-(pyrrolidine-1-carbonyl)anilino]thieno[3,2-d]pyrimidin-4-yl}amino)bicyclo[2.2.1]hept-5-ene-2-carboxamide | Human | Show | |
| IRAK4 | IRAK | TKL | 8tvm | A | A | n-{1-[(1r,2r)-2-fluorocyclopropyl]-2-oxo-1,2-dihydropyridin-3-yl}-2-[(1r,4r)-1-methyl-2-oxabicyclo[2.1.1]hexan-4-yl]-6-[(propan-2-yl)oxy]-2h-pyrazolo[3,4-b]pyridine-5-carboxamide | Human | Show | |
| IRAK4 | IRAK | TKL | 8tvm | A | B | n-{1-[(1r,2r)-2-fluorocyclopropyl]-2-oxo-1,2-dihydropyridin-3-yl}-2-[(1r,4r)-1-methyl-2-oxabicyclo[2.1.1]hexan-4-yl]-6-[(propan-2-yl)oxy]-2h-pyrazolo[3,4-b]pyridine-5-carboxamide | Human | Show | |
| IRAK4 | IRAK | TKL | 8tvn | A | A | n-{1-[(1r,2s)-2-fluorocyclopropyl]-2-oxo-1,2-dihydropyridin-3-yl}-2-[(1r,4r)-1-methyl-2-oxabicyclo[2.1.1]hexan-4-yl]-6-[(propan-2-yl)oxy]-2h-pyrazolo[3,4-b]pyridine-5-carboxamide | Human | Show | |
| IRAK4 | IRAK | TKL | 8tvn | A | B | n-{1-[(1r,2s)-2-fluorocyclopropyl]-2-oxo-1,2-dihydropyridin-3-yl}-2-[(1r,4r)-1-methyl-2-oxabicyclo[2.1.1]hexan-4-yl]-6-[(propan-2-yl)oxy]-2h-pyrazolo[3,4-b]pyridine-5-carboxamide | Human | Show | |
| IRAK4 | IRAK | TKL | 8tx0 | A | ~{n}-(1-cyclopropyl-2-oxidanylidene-pyridin-3-yl)-2-(1-methyl-2-oxabicyclo[2.1.1]hexan-4-yl)-7-propan-2-yloxy-imidazo[1,2-a]pyrimidine-6-carboxamide | Human | Show | | |
| IRAK4 | IRAK | TKL | 8ucb | A | 6-(difluoromethyl)-n-[(4r)-7-ethoxy-2-{[(3r)-oxolan-3-yl]methyl}imidazo[1,2-a]pyridin-6-yl]pyridine-2-carboxamide | Human | Show | | |
| IRAK4 | IRAK | TKL | 8ucc | A | (4s)-2-[(1r,4s)-1-methyl-2-oxabicyclo[2.1.1]hexan-4-yl]-n-[(8s)-6-methylpyrazolo[1,5-a]pyrimidin-3-yl]-7-[(propan-2-yl)oxy]imidazo[1,2-a]pyrimidine-6-carboxamide | Human | Show | | |
| IRAK4 | IRAK | TKL | 8ucc | B | (4s)-2-[(1r,4s)-1-methyl-2-oxabicyclo[2.1.1]hexan-4-yl]-n-[(8s)-6-methylpyrazolo[1,5-a]pyrimidin-3-yl]-7-[(propan-2-yl)oxy]imidazo[1,2-a]pyrimidine-6-carboxamide | Human | Show | | |
| IRAK4 | IRAK | TKL | 8v1o | A | n-[2-(3-hydroxy-3-methylbutyl)-6-(2-hydroxypropan-2-yl)-2h-indazol-5-yl]-6-(trifluoromethyl)pyridine-2-carboxamide | Human | Show | | |
| IRAK4 | IRAK | TKL | 8v2f | A | A | n-{2-[(1r,4r)-4-(hydroxymethyl)cyclohexyl]-6-(2-hydroxypropan-2-yl)-2h-indazol-5-yl}-6-(trifluoromethyl)pyridine-2-carboxamide | Human | Show | |
| IRAK4 | IRAK | TKL | 8v2f | A | B | n-{2-[(1r,4r)-4-(hydroxymethyl)cyclohexyl]-6-(2-hydroxypropan-2-yl)-2h-indazol-5-yl}-6-(trifluoromethyl)pyridine-2-carboxamide | Human | Show | |
| IRAK4 | IRAK | TKL | 8v2l | A | A | n-{2-[4-(hydroxymethyl)phenyl]-6-(2-hydroxypropan-2-yl)-2h-indazol-5-yl}-6-(trifluoromethyl)pyridine-2-carboxamide | Human | Show | |
| IRAK4 | IRAK | TKL | 8v2l | A | B | n-{2-[4-(hydroxymethyl)phenyl]-6-(2-hydroxypropan-2-yl)-2h-indazol-5-yl}-6-(trifluoromethyl)pyridine-2-carboxamide | Human | Show | |
| IRAK4 | IRAK | TKL | 8wtf | A | A | 1-{[(2s,3s,4s)-3-ethyl-4-fluoro-5-oxopyrrolidin-2-yl]methoxy}-7-methoxyisoquinoline-6-carboxamide | Human | Show | |
| IRAK4 | IRAK | TKL | 8wtf | A | B | 1-{[(2s,3s,4s)-3-ethyl-4-fluoro-5-oxopyrrolidin-2-yl]methoxy}-7-methoxyisoquinoline-6-carboxamide | Human | Show | |
| ITK | Tec | TK | 1sm2 | A | staurosporine | Human | Show | | |
| ITK | Tec | TK | 1sm2 | B | staurosporine | Human | Show | | |
| ITK | Tec | TK | 1snu | A | staurosporine | Human | Show | | |
| ITK | Tec | TK | 1snu | B | staurosporine | Human | Show | | |
| ITK | Tec | TK | 1snx | A | - | Human | Show | | |
| ITK | Tec | TK | 1snx | B | - | Human | Show | | |
| ITK | Tec | TK | 3miy | A | n-[2-(diethylamino)ethyl]-5-[(z)-(5-fluoro-2-oxo-1,2-dihydro-3h-indol-3-ylidene)methyl]-2,4-dimethyl-1h-pyrrole-3-carboxamide | Human | Show | | |
| ITK | Tec | TK | 3miy | B | n-[2-(diethylamino)ethyl]-5-[(z)-(5-fluoro-2-oxo-1,2-dihydro-3h-indol-3-ylidene)methyl]-2,4-dimethyl-1h-pyrrole-3-carboxamide | Human | Show | | |
| ITK | Tec | TK | 3mj1 | A | 7-[(4-methylpiperazin-1-yl)methyl]-4-[(3-methyl-1h-pyrazol-5-yl)amino]-2-(tetrahydro-2h-pyran-4-yl)phthalazin-1(2h)-one | Human | Show | | |
| ITK | Tec | TK | 3mj2 | A | n-[5-({5-[(4-acetylpiperazin-1-yl)carbonyl]-4-methoxy-2-methylphenyl}sulfanyl)-1,3-thiazol-2-yl]-4-({[(1s)-1,2,2-trimethylpropyl]amino}methyl)benzamide | Human | Show | | |
| ITK | Tec | TK | 3qgw | A | A | 3-[(8-phenylthieno[2,3-h]quinazolin-2-yl)amino]benzenesulfonamide | Human | Show | |
| ITK | Tec | TK | 3qgw | A | B | 3-[(8-phenylthieno[2,3-h]quinazolin-2-yl)amino]benzenesulfonamide | Human | Show | |
| ITK | Tec | TK | 3qgw | B | A | n-(6-oxo-1,6-dihydro-3,4'-bipyridin-5-yl)benzamide | Human | Show | |
| ITK | Tec | TK | 3qgw | B | B | n-(6-oxo-1,6-dihydro-3,4'-bipyridin-5-yl)benzamide | Human | Show | |
| ITK | Tec | TK | 3qgy | A | A | 3-[(8-phenylthieno[2,3-h]quinazolin-2-yl)amino]benzenesulfonamide | Human | Show | |
| ITK | Tec | TK | 3qgy | A | B | 3-[(8-phenylthieno[2,3-h]quinazolin-2-yl)amino]benzenesulfonamide | Human | Show | |
| ITK | Tec | TK | 3qgy | B | A | n-{5-[2-(methylamino)pyrimidin-4-yl]-2-oxo-1,2-dihydropyridin-3-yl}-4-(piperidin-1-yl)benzamide | Human | Show | |
| ITK | Tec | TK | 3qgy | B | B | n-{5-[2-(methylamino)pyrimidin-4-yl]-2-oxo-1,2-dihydropyridin-3-yl}-4-(piperidin-1-yl)benzamide | Human | Show | |
| ITK | Tec | TK | 3t9t | A | A | (2z)-4-(dimethylamino)-n-{7-fluoro-4-[(2-methylphenyl)amino]imidazo[1,5-a]quinoxalin-8-yl}-n-methylbut-2-enamide | Human | Show | |
| ITK | Tec | TK | 3t9t | A | B | (2z)-4-(dimethylamino)-n-{7-fluoro-4-[(2-methylphenyl)amino]imidazo[1,5-a]quinoxalin-8-yl}-n-methylbut-2-enamide | Human | Show | |
| ITK | Tec | TK | 3v5j | A | 3-{4-[2-(morpholin-4-yl)ethoxy]-2-(4lambda~4~-thieno[3,2-c]pyrazol-3-yl)-1h-indol-6-yl}pentan-3-ol | Human | Show | | |
| ITK | Tec | TK | 3v5j | B | 3-{4-[2-(morpholin-4-yl)ethoxy]-2-(4lambda~4~-thieno[3,2-c]pyrazol-3-yl)-1h-indol-6-yl}pentan-3-ol | Human | Show | |
