PDB-code
Browse kinase entries (page 146 of 282)
First 142 143 144 PreviousLast150 149 148 Next| # | Kinase | Family | Group | PDB | Chain | (Alternate) Model | Orthosteric ligand | Organism | Details | File |
|---|---|---|---|---|---|---|---|---|---|---|
 | ITK | Tec | TK | 3v5l | A | 3-[3-(4-methoxyphenyl)-2-(1h-thieno[3,2-c]pyrazol-3-yl)-1h-indol-6-yl]pentan-3-ol | Human | Show |  | |
| ITK | Tec | TK | 3v5l | B | 3-[3-(4-methoxyphenyl)-2-(1h-thieno[3,2-c]pyrazol-3-yl)-1h-indol-6-yl]pentan-3-ol | Human | Show | | |
| ITK | Tec | TK | 3v5l | C | 3-[3-(4-methoxyphenyl)-2-(1h-thieno[3,2-c]pyrazol-3-yl)-1h-indol-6-yl]pentan-3-ol | Human | Show | | |
| ITK | Tec | TK | 3v5l | D | 3-[3-(4-methoxyphenyl)-2-(1h-thieno[3,2-c]pyrazol-3-yl)-1h-indol-6-yl]pentan-3-ol | Human | Show | | |
| ITK | Tec | TK | 3v8t | A | A | 3-{2-[5-(difluoromethyl)-2h-thieno[3,2-c]pyrazol-3-yl]-1h-indol-6-yl}pentan-3-ol | Human | Show | |
| ITK | Tec | TK | 3v8t | A | B | 3-{2-[5-(difluoromethyl)-2h-thieno[3,2-c]pyrazol-3-yl]-1h-indol-6-yl}pentan-3-ol | Human | Show | |
| ITK | Tec | TK | 3v8t | B | A | 3-{2-[5-(difluoromethyl)-2h-thieno[3,2-c]pyrazol-3-yl]-1h-indol-6-yl}pentan-3-ol | Human | Show | |
| ITK | Tec | TK | 3v8t | B | B | 3-{2-[5-(difluoromethyl)-2h-thieno[3,2-c]pyrazol-3-yl]-1h-indol-6-yl}pentan-3-ol | Human | Show | |
| ITK | Tec | TK | 3v8w | A | 3-[2-(5-phenyl-2h-thieno[3,2-c]pyrazol-3-yl)-1h-indol-6-yl]pentan-3-ol | Human | Show | | |
| ITK | Tec | TK | 3v8w | B | 3-[2-(5-phenyl-2h-thieno[3,2-c]pyrazol-3-yl)-1h-indol-6-yl]pentan-3-ol | Human | Show | | |
| ITK | Tec | TK | 4hct | A | 3-{1-[(3r)-1-acryloylpiperidin-3-yl]-4-amino-1h-pyrazolo[3,4-d]pyrimidin-3-yl}-n-(3-tert-butylphenyl)benzamide | Human | Show | | |
| ITK | Tec | TK | 4hcu | A | 3-{4-amino-1-[(3r)-1-propanoylpiperidin-3-yl]-1h-pyrazolo[3,4-d]pyrimidin-3-yl}-n-[4-(propan-2-yl)phenyl]benzamide | Human | Show | | |
| ITK | Tec | TK | 4hcv | A | 3-{4-amino-1-[(3s)-1-propanoylpiperidin-3-yl]-1h-pyrazolo[3,4-d]pyrimidin-3-yl}-n-[4-(propan-2-yl)phenyl]benzamide | Human | Show | | |
| ITK | Tec | TK | 4kio | A | A | 1-[(3s)-3-{[4-(morpholin-4-ylmethyl)-6-([1,3]thiazolo[5,4-b]pyridin-2-ylamino)pyrimidin-2-yl]amino}pyrrolidin-1-yl]prop-2-en-1-one | Human | Show | |
| ITK | Tec | TK | 4kio | A | B | 1-[(3s)-3-{[4-(morpholin-4-ylmethyl)-6-([1,3]thiazolo[5,4-b]pyridin-2-ylamino)pyrimidin-2-yl]amino}pyrrolidin-1-yl]prop-2-en-1-one | Human | Show | |
| ITK | Tec | TK | 4kio | B | A | 1-[(3s)-3-{[4-(morpholin-4-ylmethyl)-6-([1,3]thiazolo[5,4-b]pyridin-2-ylamino)pyrimidin-2-yl]amino}pyrrolidin-1-yl]prop-2-en-1-one | Human | Show | |
| ITK | Tec | TK | 4kio | B | B | 1-[(3s)-3-{[4-(morpholin-4-ylmethyl)-6-([1,3]thiazolo[5,4-b]pyridin-2-ylamino)pyrimidin-2-yl]amino}pyrrolidin-1-yl]prop-2-en-1-one | Human | Show | |
| ITK | Tec | TK | 4kio | C | A | 1-[(3s)-3-{[4-(morpholin-4-ylmethyl)-6-([1,3]thiazolo[5,4-b]pyridin-2-ylamino)pyrimidin-2-yl]amino}pyrrolidin-1-yl]propan-1-one | Human | Show | |
| ITK | Tec | TK | 4kio | C | B | 1-[(3s)-3-{[4-(morpholin-4-ylmethyl)-6-([1,3]thiazolo[5,4-b]pyridin-2-ylamino)pyrimidin-2-yl]amino}pyrrolidin-1-yl]prop-2-en-1-one | Human | Show | |
| ITK | Tec | TK | 4kio | D | A | 1-[(3s)-3-{[4-(morpholin-4-ylmethyl)-6-([1,3]thiazolo[5,4-b]pyridin-2-ylamino)pyrimidin-2-yl]amino}pyrrolidin-1-yl]propan-1-one | Human | Show | |
| ITK | Tec | TK | 4kio | D | B | 1-[(3s)-3-{[4-(morpholin-4-ylmethyl)-6-([1,3]thiazolo[5,4-b]pyridin-2-ylamino)pyrimidin-2-yl]amino}pyrrolidin-1-yl]propan-1-one | Human | Show | |
| ITK | Tec | TK | 4l7s | A | A | trans-4-({4-[difluoro(4-fluorophenyl)methyl]-6-[(5-methoxy[1,3]thiazolo[5,4-b]pyridin-2-yl)amino]pyrimidin-2-yl}amino)cyclohexanol | Human | Show | |
| ITK | Tec | TK | 4l7s | A | B | trans-4-({4-[difluoro(4-fluorophenyl)methyl]-6-[(5-methoxy[1,3]thiazolo[5,4-b]pyridin-2-yl)amino]pyrimidin-2-yl}amino)cyclohexanol | Human | Show | |
| ITK | Tec | TK | 4l7s | B | A | trans-4-({4-[difluoro(4-fluorophenyl)methyl]-6-[(5-methoxy[1,3]thiazolo[5,4-b]pyridin-2-yl)amino]pyrimidin-2-yl}amino)cyclohexanol | Human | Show | |
| ITK | Tec | TK | 4l7s | B | B | trans-4-({4-[difluoro(4-fluorophenyl)methyl]-6-[(5-methoxy[1,3]thiazolo[5,4-b]pyridin-2-yl)amino]pyrimidin-2-yl}amino)cyclohexanol | Human | Show | |
| ITK | Tec | TK | 4m0y | A | A | 4-(carbamoylamino)-1-(naphthalen-1-yl)-1h-pyrazole-3-carboxamide | Human | Show | |
| ITK | Tec | TK | 4m0y | A | B | 4-(carbamoylamino)-1-(naphthalen-1-yl)-1h-pyrazole-3-carboxamide | Human | Show | |
| ITK | Tec | TK | 4m0z | A | A | 4-(carbamoylamino)-1-(7-methoxynaphthalen-1-yl)-1h-pyrazole-3-carboxamide | Human | Show | |
| ITK | Tec | TK | 4m0z | A | B | 4-(carbamoylamino)-1-(7-methoxynaphthalen-1-yl)-1h-pyrazole-3-carboxamide | Human | Show | |
| ITK | Tec | TK | 4m12 | A | A | - | Human | Show | |
| ITK | Tec | TK | 4m12 | A | B | - | Human | Show | |
| ITK | Tec | TK | 4m13 | A | A | - | Human | Show | |
| ITK | Tec | TK | 4m13 | A | B | - | Human | Show | |
| ITK | Tec | TK | 4m14 | A | 4-(carbamoylamino)-1-[7-(propan-2-yloxy)naphthalen-1-yl]-1h-pyrazole-3-carboxamide | Human | Show | | |
| ITK | Tec | TK | 4m15 | A | adenosine-5'-diphosphate | Human | Show | | |
| ITK | Tec | TK | 4mf0 | A | (1s,2s)-2-{4-[(dimethylamino)methyl]phenyl}-n-[6-(pyridin-3-yl)-1,3-benzothiazol-2-yl]cyclopropanecarboxamide | Human | Show | | |
| ITK | Tec | TK | 4mf0 | B | (1s,2s)-2-{4-[(dimethylamino)methyl]phenyl}-n-[6-(pyridin-3-yl)-1,3-benzothiazol-2-yl]cyclopropanecarboxamide | Human | Show | | |
| ITK | Tec | TK | 4mf1 | A | A | (1s,2s)-2-{4-[(dimethylamino)methyl]phenyl}-n-[6-(1h-pyrazol-4-yl)-1,3-benzothiazol-2-yl]cyclopropanecarboxamide | Human | Show | |
| ITK | Tec | TK | 4mf1 | A | B | (1s,2s)-2-{4-[(dimethylamino)methyl]phenyl}-n-[6-(1h-pyrazol-4-yl)-1,3-benzothiazol-2-yl]cyclopropanecarboxamide | Human | Show | |
| ITK | Tec | TK | 4mf1 | B | A | (1s,2s)-2-{4-[(dimethylamino)methyl]phenyl}-n-[6-(1h-pyrazol-4-yl)-1,3-benzothiazol-2-yl]cyclopropanecarboxamide | Human | Show | |
| ITK | Tec | TK | 4mf1 | B | B | (1s,2s)-2-{4-[(dimethylamino)methyl]phenyl}-n-[6-(1h-pyrazol-4-yl)-1,3-benzothiazol-2-yl]cyclopropanecarboxamide | Human | Show | |
| ITK | Tec | TK | 4pp9 | A | n-[1-(3-cyanobenzyl)-1h-pyrazol-4-yl]-2h-indazole-3-carboxamide | Human | Show | | |
| ITK | Tec | TK | 4pp9 | B | n-[1-(3-cyanobenzyl)-1h-pyrazol-4-yl]-2h-indazole-3-carboxamide | Human | Show | | |
| ITK | Tec | TK | 4ppa | A | n-[1-(3-cyanobenzyl)-1h-pyrazol-4-yl]-6-(1h-pyrazol-4-yl)-1h-indazole-3-carboxamide | Human | Show | | |
| ITK | Tec | TK | 4ppa | B | n-[1-(3-cyanobenzyl)-1h-pyrazol-4-yl]-6-(1h-pyrazol-4-yl)-1h-indazole-3-carboxamide | Human | Show | | |
| ITK | Tec | TK | 4ppb | A | n-{1-[(1s)-3-(dimethylamino)-1-phenylpropyl]-1h-pyrazol-4-yl}-6-(1h-pyrazol-4-yl)-1h-indazole-3-carboxamide | Human | Show | | |
| ITK | Tec | TK | 4ppb | B | n-{1-[(1s)-3-(dimethylamino)-1-phenylpropyl]-1h-pyrazol-4-yl}-6-(1h-pyrazol-4-yl)-1h-indazole-3-carboxamide | Human | Show | | |
| ITK | Tec | TK | 4ppc | A | A | n-{1-[(1r)-3-(dimethylamino)-1-phenylpropyl]-1h-pyrazol-4-yl}-6-(1h-pyrazol-4-yl)-1h-indazole-3-carboxamide | Human | Show | |
| ITK | Tec | TK | 4ppc | A | B | n-{1-[(1r)-3-(dimethylamino)-1-phenylpropyl]-1h-pyrazol-4-yl}-6-(1h-pyrazol-4-yl)-1h-indazole-3-carboxamide | Human | Show | |
| ITK | Tec | TK | 4ppc | B | A | n-{1-[(1r)-3-(dimethylamino)-1-phenylpropyl]-1h-pyrazol-4-yl}-6-(1h-pyrazol-4-yl)-1h-indazole-3-carboxamide | Human | Show | |
