PDB-code
Browse kinase entries (page 148 of 282)
First 144 145 146 PreviousLast152 151 150 Next| # | Kinase | Family | Group | PDB | Chain | (Alternate) Model | Orthosteric ligand | Organism | Details | File |
|---|---|---|---|---|---|---|---|---|---|---|
 | JAK1 | JakA | TK | 4ivc | B | (trans-4-{2-[(1r)-1-hydroxyethyl]imidazo[4,5-d]pyrrolo[2,3-b]pyridin-1(6h)-yl}cyclohexyl)acetonitrile | Human | Show |  | |
| JAK1 | JakA | TK | 4ivd | A | A | 3-(trans-4-{2-[(1r)-1-hydroxyethyl]imidazo[4,5-d]pyrrolo[2,3-b]pyridin-1(6h)-yl}cyclohexyl)propanenitrile | Human | Show | |
| JAK1 | JakA | TK | 4ivd | A | B | 3-(trans-4-{2-[(1r)-1-hydroxyethyl]imidazo[4,5-d]pyrrolo[2,3-b]pyridin-1(6h)-yl}cyclohexyl)propanenitrile | Human | Show | |
| JAK1 | JakA | TK | 4ivd | B | A | 3-(trans-4-{2-[(1r)-1-hydroxyethyl]imidazo[4,5-d]pyrrolo[2,3-b]pyridin-1(6h)-yl}cyclohexyl)propanenitrile | Human | Show | |
| JAK1 | JakA | TK | 4ivd | B | B | 3-(trans-4-{2-[(1r)-1-hydroxyethyl]imidazo[4,5-d]pyrrolo[2,3-b]pyridin-1(6h)-yl}cyclohexyl)propanenitrile | Human | Show | |
| JAK1 | JakA | TK | 4k6z | A | (1r,2s)-2-{[8-oxo-2-(1h-pyrazol-4-yl)-5,8-dihydropyrido[3,4-d]pyrimidin-4-yl]amino}cyclopentanecarbonitrile | Human | Show | | |
| JAK1 | JakA | TK | 4k77 | A | 4-(cyclohexylamino)pyrido[3,4-d]pyrimidin-8(7h)-one | Human | Show | | |
| JAK1 | JakA | TK | 4k77 | B | 4-(cyclohexylamino)pyrido[3,4-d]pyrimidin-8(7h)-one | Human | Show | | |
| JAK1 | JakA | TK | 5e1e | A | A | 6-chloro-2-(2-fluoro-4,5-dimethoxyphenyl)-n-(piperidin-4-ylmethyl)-3h-imidazo[4,5-b]pyridin-7-amine | Human | Show | |
| JAK1 | JakA | TK | 5e1e | A | B | 6-chloro-2-(2-fluoro-4,5-dimethoxyphenyl)-n-(piperidin-4-ylmethyl)-3h-imidazo[4,5-b]pyridin-7-amine | Human | Show | |
| JAK1 | JakA | TK | 5e1e | B | A | 6-chloro-2-(2-fluoro-4,5-dimethoxyphenyl)-n-(piperidin-4-ylmethyl)-3h-imidazo[4,5-b]pyridin-7-amine | Human | Show | |
| JAK1 | JakA | TK | 5e1e | B | B | 6-chloro-2-(2-fluoro-4,5-dimethoxyphenyl)-n-(piperidin-4-ylmethyl)-3h-imidazo[4,5-b]pyridin-7-amine | Human | Show | |
| JAK1 | JakA | TK | 5hx8 | A | A | 4-[(4-aminocyclohexyl)amino]-3-(1h-benzimidazol-2-yl)-1h-pyridin-2-one | Human | Show | |
| JAK1 | JakA | TK | 5hx8 | A | B | 4-[(4-aminocyclohexyl)amino]-3-(1h-benzimidazol-2-yl)-1h-pyridin-2-one | Human | Show | |
| JAK1 | JakA | TK | 5hx8 | B | A | 4-[(4-aminocyclohexyl)amino]-3-(1h-benzimidazol-2-yl)-1h-pyridin-2-one | Human | Show | |
| JAK1 | JakA | TK | 5hx8 | B | B | 4-[(4-aminocyclohexyl)amino]-3-(1h-benzimidazol-2-yl)-1h-pyridin-2-one | Human | Show | |
| JAK1 | JakA | TK | 5khw | A | adenosine-5'-diphosphate | Human | Show | | |
| JAK1 | JakA | TK | 5khw | B | adenosine-5'-diphosphate | Human | Show | | |
| JAK1 | JakA | TK | 5khx | A | A | ~{n}-[3-[methyl(7~{h}-pyrrolo[2,3-d]pyrimidin-4-yl)amino]cyclobutyl]methanesulfonamide | Human | Show | |
| JAK1 | JakA | TK | 5khx | A | B | ~{n}-[3-[methyl(7~{h}-pyrrolo[2,3-d]pyrimidin-4-yl)amino]cyclobutyl]methanesulfonamide | Human | Show | |
| JAK1 | JakA | TK | 5wo4 | A | A | 3-[(4-chloro-3-methoxyphenyl)amino]-1-[(3r,4s)-4-cyanooxan-3-yl]-1h-pyrazole-4-carboxamide | Human | Show | |
| JAK1 | JakA | TK | 5wo4 | A | B | 3-[(4-chloro-3-methoxyphenyl)amino]-1-[(3r,4s)-4-cyanooxan-3-yl]-1h-pyrazole-4-carboxamide | Human | Show | |
| JAK1 | JakA | TK | 5wo4 | B | A | 3-[(4-chloro-3-methoxyphenyl)amino]-1-[(3r,4s)-4-cyanooxan-3-yl]-1h-pyrazole-4-carboxamide | Human | Show | |
| JAK1 | JakA | TK | 5wo4 | B | B | 3-[(4-chloro-3-methoxyphenyl)amino]-1-[(3r,4s)-4-cyanooxan-3-yl]-1h-pyrazole-4-carboxamide | Human | Show | |
| JAK1 | JakA | TK | 6aah | A | A | 4-[[(1s,3r)-5-oxidanyl-2-adamantyl]amino]-1h-pyrrolo[2,3-b]pyridine-5-carboxamide | Human | Show | |
| JAK1 | JakA | TK | 6aah | A | B | 4-[[(1s,3r)-5-oxidanyl-2-adamantyl]amino]-1h-pyrrolo[2,3-b]pyridine-5-carboxamide | Human | Show | |
| JAK1 | JakA | TK | 6aah | B | A | 4-[[(1s,3r)-5-oxidanyl-2-adamantyl]amino]-1h-pyrrolo[2,3-b]pyridine-5-carboxamide | Human | Show | |
| JAK1 | JakA | TK | 6aah | B | B | 4-[[(1s,3r)-5-oxidanyl-2-adamantyl]amino]-1h-pyrrolo[2,3-b]pyridine-5-carboxamide | Human | Show | |
| JAK1 | JakA | TK | 6bbu | A | A | n-{cis-3-[methyl(7h-pyrrolo[2,3-d]pyrimidin-4-yl)amino]cyclobutyl}propane-1-sulfonamide | Human | Show | |
| JAK1 | JakA | TK | 6bbu | A | B | n-{cis-3-[methyl(7h-pyrrolo[2,3-d]pyrimidin-4-yl)amino]cyclobutyl}propane-1-sulfonamide | Human | Show | |
| JAK1 | JakA | TK | 6c7y | A | A | adenosine-5'-diphosphate | Human | Show | |
| JAK1 | JakA | TK | 6c7y | A | B | adenosine-5'-diphosphate | Human | Show | |
| JAK1 | JakA | TK | 6dbn | A | A | [(1s)-2,2-difluorocyclopropyl][(1r,5s)-3-{2-[(1-methyl-1h-pyrazol-4-yl)amino]pyrimidin-4-yl}-3,8-diazabicyclo[3.2.1]octan-8-yl]methanone | Human | Show | |
| JAK1 | JakA | TK | 6dbn | A | B | [(1s)-2,2-difluorocyclopropyl][(1r,5s)-3-{2-[(1-methyl-1h-pyrazol-4-yl)amino]pyrimidin-4-yl}-3,8-diazabicyclo[3.2.1]octan-8-yl]methanone | Human | Show | |
| JAK1 | JakA | TK | 6elr | A | A | [3-[[5-methyl-2-[[3-(4-methylpiperazin-1-yl)-5-methylsulfonyl-phenyl]amino]pyrimidin-4-yl]amino]phenyl]methanol | Human | Show | |
| JAK1 | JakA | TK | 6elr | A | B | [3-[[5-methyl-2-[[3-(4-methylpiperazin-1-yl)-5-methylsulfonyl-phenyl]amino]pyrimidin-4-yl]amino]phenyl]methanol | Human | Show | |
| JAK1 | JakA | TK | 6elr | B | A | [3-[[5-methyl-2-[[3-(4-methylpiperazin-1-yl)-5-methylsulfonyl-phenyl]amino]pyrimidin-4-yl]amino]phenyl]methanol | Human | Show | |
| JAK1 | JakA | TK | 6elr | B | B | [3-[[5-methyl-2-[[3-(4-methylpiperazin-1-yl)-5-methylsulfonyl-phenyl]amino]pyrimidin-4-yl]amino]phenyl]methanol | Human | Show | |
| JAK1 | JakA | TK | 6ggh | A | A | ~{n}-[5-methyl-4-[7-[[(2~{r})-2-(4-methylpiperazin-1-yl)propanoyl]amino]-1~{h}-indol-3-yl]pyrimidin-2-yl]cyclopropanecarboxamide | Human | Show | |
| JAK1 | JakA | TK | 6ggh | A | B | ~{n}-[5-methyl-4-[7-[[(2~{r})-2-(4-methylpiperazin-1-yl)propanoyl]amino]-1~{h}-indol-3-yl]pyrimidin-2-yl]cyclopropanecarboxamide | Human | Show | |
| JAK1 | JakA | TK | 6ggh | B | A | ~{n}-[5-methyl-4-[7-[[(2~{r})-2-(4-methylpiperazin-1-yl)propanoyl]amino]-1~{h}-indol-3-yl]pyrimidin-2-yl]cyclopropanecarboxamide | Human | Show | |
| JAK1 | JakA | TK | 6ggh | B | B | ~{n}-[5-methyl-4-[7-[[(2~{r})-2-(4-methylpiperazin-1-yl)propanoyl]amino]-1~{h}-indol-3-yl]pyrimidin-2-yl]cyclopropanecarboxamide | Human | Show | |
| JAK1 | JakA | TK | 6hzu | A | A | 2-[4-[8-oxidanylidene-2-[(~{e})-(2-oxidanylidenepyridin-3-ylidene)amino]-7~{h}-purin-9-yl]cyclohexyl]ethanenitrile | Human | Show | |
| JAK1 | JakA | TK | 6hzu | A | B | 2-[4-[8-oxidanylidene-2-[(~{e})-(2-oxidanylidenepyridin-3-ylidene)amino]-7~{h}-purin-9-yl]cyclohexyl]ethanenitrile | Human | Show | |
| JAK1 | JakA | TK | 6hzu | B | A | 2-[4-[8-oxidanylidene-2-[(~{e})-(2-oxidanylidenepyridin-3-ylidene)amino]-7~{h}-purin-9-yl]cyclohexyl]ethanenitrile | Human | Show | |
| JAK1 | JakA | TK | 6hzu | B | B | 2-[4-[8-oxidanylidene-2-[(~{e})-(2-oxidanylidenepyridin-3-ylidene)amino]-7~{h}-purin-9-yl]cyclohexyl]ethanenitrile | Human | Show | |
| JAK1 | JakA | TK | 6n77 | A | A | n-[3-(5-chloro-2-methoxyphenyl)-1-methyl-1h-pyrazol-4-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide | Human | Show | |
| JAK1 | JakA | TK | 6n77 | A | B | n-[3-(5-chloro-2-methoxyphenyl)-1-methyl-1h-pyrazol-4-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide | Human | Show | |
| JAK1 | JakA | TK | 6n77 | A | C | n-[3-(5-chloro-2-methoxyphenyl)-1-methyl-1h-pyrazol-4-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide | Human | Show | |
| JAK1 | JakA | TK | 6n77 | B | A | n-[3-(5-chloro-2-methoxyphenyl)-1-methyl-1h-pyrazol-4-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide | Human | Show | |
