PDB-code
Browse kinase entries (page 150 of 282)
First 146 147 148 PreviousLast154 153 152 Next| # | Kinase | Family | Group | PDB | Chain | (Alternate) Model | Orthosteric ligand | Organism | Details | File |
|---|---|---|---|---|---|---|---|---|---|---|
 | JAK1-b | JakB | TK | 4l00 | A | B | - | Human | Show |  |
| JAK1-b | JakB | TK | 4l00 | B | A | - | Human | Show | |
| JAK1-b | JakB | TK | 4l00 | B | B | - | Human | Show | |
| JAK1-b | JakB | TK | 4l01 | A | A | - | Human | Show | |
| JAK1-b | JakB | TK | 4l01 | A | B | - | Human | Show | |
| JAK1-b | JakB | TK | 4l01 | B | A | - | Human | Show | |
| JAK1-b | JakB | TK | 4l01 | B | B | - | Human | Show | |
| Jak2 (JAK2) | JakA | TK | 4gl9 | A | 2-tert-butyl-9-fluoro-3,6-dihydro-7h-benz[h]-imidaz[4,5-f]isoquinoline-7-one | Mouse | Show | | |
| Jak2 (JAK2) | JakA | TK | 4gl9 | B | 2-tert-butyl-9-fluoro-3,6-dihydro-7h-benz[h]-imidaz[4,5-f]isoquinoline-7-one | Mouse | Show | | |
| Jak2 (JAK2) | JakA | TK | 4gl9 | C | 2-tert-butyl-9-fluoro-3,6-dihydro-7h-benz[h]-imidaz[4,5-f]isoquinoline-7-one | Mouse | Show | | |
| Jak2 (JAK2) | JakA | TK | 4gl9 | D | 2-tert-butyl-9-fluoro-3,6-dihydro-7h-benz[h]-imidaz[4,5-f]isoquinoline-7-one | Mouse | Show | | |
| JAK2 | JakA | TK | 2b7a | A | 2-tert-butyl-9-fluoro-3,6-dihydro-7h-benz[h]-imidaz[4,5-f]isoquinoline-7-one | Human | Show | | |
| JAK2 | JakA | TK | 2b7a | B | 2-tert-butyl-9-fluoro-3,6-dihydro-7h-benz[h]-imidaz[4,5-f]isoquinoline-7-one | Human | Show | | |
| JAK2 | JakA | TK | 2w1i | A | 4-[(2-{4-[(cyclopropylcarbamoyl)amino]-1h-pyrazol-3-yl}-1h-benzimidazol-6-yl)methyl]morpholin-4-ium | Human | Show | | |
| JAK2 | JakA | TK | 2w1i | B | - | Human | Show | | |
| JAK2 | JakA | TK | 2xa4 | A | A | 5-chloro-n2-[(1s)-1-(5-fluoropyrimidin-2-yl)ethyl]-n4-(5-methyl-1h-pyrazol-3-yl)pyrimidine-2,4-diamine | Human | Show | |
| JAK2 | JakA | TK | 2xa4 | A | B | 5-chloro-n2-[(1s)-1-(5-fluoropyrimidin-2-yl)ethyl]-n4-(5-methyl-1h-pyrazol-3-yl)pyrimidine-2,4-diamine | Human | Show | |
| JAK2 | JakA | TK | 2xa4 | B | A | 5-chloro-n2-[(1s)-1-(5-fluoropyrimidin-2-yl)ethyl]-n4-(5-methyl-1h-pyrazol-3-yl)pyrimidine-2,4-diamine | Human | Show | |
| JAK2 | JakA | TK | 2xa4 | B | B | 5-chloro-n2-[(1s)-1-(5-fluoropyrimidin-2-yl)ethyl]-n4-(5-methyl-1h-pyrazol-3-yl)pyrimidine-2,4-diamine | Human | Show | |
| JAK2 | JakA | TK | 3e62 | A | A | 5-bromo-1h-indazol-3-amine | Human | Show | |
| JAK2 | JakA | TK | 3e62 | A | B | 5-bromo-1h-indazol-3-amine | Human | Show | |
| JAK2 | JakA | TK | 3e63 | A | A | 5-phenyl-1h-indazol-3-amine | Human | Show | |
| JAK2 | JakA | TK | 3e63 | A | B | 5-phenyl-1h-indazol-3-amine | Human | Show | |
| JAK2 | JakA | TK | 3e64 | A | A | 4-(3-amino-1h-indazol-5-yl)-n-tert-butylbenzenesulfonamide | Human | Show | |
| JAK2 | JakA | TK | 3e64 | A | B | 4-(3-amino-1h-indazol-5-yl)-n-tert-butylbenzenesulfonamide | Human | Show | |
| JAK2 | JakA | TK | 3fup | A | 3-{(3r,4r)-4-methyl-3-[methyl(7h-pyrrolo[2,3-d]pyrimidin-4-yl)amino]piperidin-1-yl}-3-oxopropanenitrile | Human | Show | | |
| JAK2 | JakA | TK | 3fup | B | 3-{(3r,4r)-4-methyl-3-[methyl(7h-pyrrolo[2,3-d]pyrimidin-4-yl)amino]piperidin-1-yl}-3-oxopropanenitrile | Human | Show | | |
| JAK2 | JakA | TK | 3io7 | A | (3s)-1-[6-(2-aminopyrazolo[1,5-a]pyrimidin-3-yl)pyrimidin-4-yl]-n,n-diethylpiperidine-3-carboxamide | Human | Show | | |
| JAK2 | JakA | TK | 3iok | A | A | 3-(6-{[(1s)-1-(4-fluorophenyl)ethyl]amino}pyrimidin-4-yl)pyrazolo[1,5-a]pyrimidin-2-amine | Human | Show | |
| JAK2 | JakA | TK | 3iok | A | B | 3-(6-{[(1s)-1-(4-fluorophenyl)ethyl]amino}pyrimidin-4-yl)pyrazolo[1,5-a]pyrimidin-2-amine | Human | Show | |
| JAK2 | JakA | TK | 3jy9 | A | A | (3s)-3-(4-hydroxyphenyl)-1,5-dihydro-1,5,12-triazabenzo[4,5]cycloocta[1,2,3-cd]inden-4(3h)-one | Human | Show | |
| JAK2 | JakA | TK | 3jy9 | A | B | (3s)-3-(4-hydroxyphenyl)-1,5-dihydro-1,5,12-triazabenzo[4,5]cycloocta[1,2,3-cd]inden-4(3h)-one | Human | Show | |
| JAK2 | JakA | TK | 3kck | A | A | 3-chloro-4-(4h-3,4,7-triazadibenzo[cd,f]azulen-6-yl)phenol | Human | Show | |
| JAK2 | JakA | TK | 3kck | A | B | 3-chloro-4-(4h-3,4,7-triazadibenzo[cd,f]azulen-6-yl)phenol | Human | Show | |
| JAK2 | JakA | TK | 3krr | A | A | 8-[3,5-difluoro-4-(morpholin-4-ylmethyl)phenyl]-2-(1-piperidin-4-yl-1h-pyrazol-4-yl)quinoxaline | Human | Show | |
| JAK2 | JakA | TK | 3krr | A | B | 8-[3,5-difluoro-4-(morpholin-4-ylmethyl)phenyl]-2-(1-piperidin-4-yl-1h-pyrazol-4-yl)quinoxaline | Human | Show | |
| JAK2 | JakA | TK | 3lpb | A | A | n-methyl-4-[3-(3,4,5-trimethoxyphenyl)quinoxalin-5-yl]benzenesulfonamide | Human | Show | |
| JAK2 | JakA | TK | 3lpb | A | B | n-methyl-4-[3-(3,4,5-trimethoxyphenyl)quinoxalin-5-yl]benzenesulfonamide | Human | Show | |
| JAK2 | JakA | TK | 3lpb | B | A | n-methyl-4-[3-(3,4,5-trimethoxyphenyl)quinoxalin-5-yl]benzenesulfonamide | Human | Show | |
| JAK2 | JakA | TK | 3lpb | B | B | n-methyl-4-[3-(3,4,5-trimethoxyphenyl)quinoxalin-5-yl]benzenesulfonamide | Human | Show | |
| JAK2 | JakA | TK | 3q32 | A | 2-(2,6-difluoro-4-methoxyphenyl)-1-(4-{4-[(3-methyl-1h-pyrazol-5-yl)amino]pyrrolo[2,1-f][1,2,4]triazin-2-yl}piperazin-1-yl)ethanone | Human | Show | | |
| JAK2 | JakA | TK | 3q32 | B | 2-(2,6-difluoro-4-methoxyphenyl)-1-(4-{4-[(3-methyl-1h-pyrazol-5-yl)amino]pyrrolo[2,1-f][1,2,4]triazin-2-yl}piperazin-1-yl)ethanone | Human | Show | | |
| JAK2 | JakA | TK | 3rvg | A | 1-(cyclohexylamino)-7-(1-methyl-1h-pyrazol-4-yl)-5h-pyrido[4,3-b]indole-4-carboxamide | Human | Show | | |
| JAK2 | JakA | TK | 3tjc | A | 4-amino-n-methyl-2-[4-(morpholin-4-yl)phenyl]thieno[3,2-c]pyridine-7-carboxamide | Human | Show | | |
| JAK2 | JakA | TK | 3tjc | B | 4-amino-n-methyl-2-[4-(morpholin-4-yl)phenyl]thieno[3,2-c]pyridine-7-carboxamide | Human | Show | | |
| JAK2 | JakA | TK | 3tjd | A | 4-amino-2-[4-(tert-butylsulfamoyl)phenyl]-n-methylthieno[3,2-c]pyridine-7-carboxamide | Human | Show | | |
| JAK2 | JakA | TK | 3tjd | B | 4-amino-2-[4-(tert-butylsulfamoyl)phenyl]-n-methylthieno[3,2-c]pyridine-7-carboxamide | Human | Show | | |
| JAK2 | JakA | TK | 3ugc | A | A | 5-{[6-(acetylamino)pyrimidin-4-yl]oxy}-n-{4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}-2,3-dihydro-1h-indole-1-carboxamide | Human | Show | |
| JAK2 | JakA | TK | 3ugc | A | B | 5-{[6-(acetylamino)pyrimidin-4-yl]oxy}-n-{4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}-2,3-dihydro-1h-indole-1-carboxamide | Human | Show | |
| JAK2 | JakA | TK | 3zmm | A | A | 5-fluoro-4-[(1s)-1-(5-fluoropyrimidin-2-yl)ethoxy]-n-(5-methyl-1h-pyrazol-3-yl)-6-morpholino-pyrimidin-2-amine | Human | Show | |
