PDB-code
Browse kinase entries (page 151 of 282)
First 147 148 149 PreviousLast155 154 153 Next| # | Kinase | Family | Group | PDB | Chain | (Alternate) Model | Orthosteric ligand | Organism | Details | File |
|---|---|---|---|---|---|---|---|---|---|---|
 | JAK2 | JakA | TK | 3zmm | A | B | 5-fluoro-4-[(1s)-1-(5-fluoropyrimidin-2-yl)ethoxy]-n-(5-methyl-1h-pyrazol-3-yl)-6-morpholino-pyrimidin-2-amine | Human | Show |  |
| JAK2 | JakA | TK | 3zmm | B | A | 5-fluoro-4-[(1s)-1-(5-fluoropyrimidin-2-yl)ethoxy]-n-(5-methyl-1h-pyrazol-3-yl)-6-morpholino-pyrimidin-2-amine | Human | Show | |
| JAK2 | JakA | TK | 3zmm | B | B | 5-fluoro-4-[(1s)-1-(5-fluoropyrimidin-2-yl)ethoxy]-n-(5-methyl-1h-pyrazol-3-yl)-6-morpholino-pyrimidin-2-amine | Human | Show | |
| JAK2 | JakA | TK | 4aqc | A | A | 8-(4-methylsulfonylphenyl)-n-(4-morpholin-4-ylphenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-amine | Human | Show | |
| JAK2 | JakA | TK | 4aqc | A | B | 8-(4-methylsulfonylphenyl)-n-(4-morpholin-4-ylphenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-amine | Human | Show | |
| JAK2 | JakA | TK | 4aqc | B | A | 8-(4-methylsulfonylphenyl)-n-(4-morpholin-4-ylphenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-amine | Human | Show | |
| JAK2 | JakA | TK | 4aqc | B | B | 8-(4-methylsulfonylphenyl)-n-(4-morpholin-4-ylphenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-amine | Human | Show | |
| JAK2 | JakA | TK | 4bbe | A | n-[4-[2-[(4-morpholin-4-ylphenyl)amino]pyrimidin-4-yl]phenyl]ethanamide | Human | Show | | |
| JAK2 | JakA | TK | 4bbe | B | n-[4-[2-[(4-morpholin-4-ylphenyl)amino]pyrimidin-4-yl]phenyl]ethanamide | Human | Show | | |
| JAK2 | JakA | TK | 4bbe | C | n-[4-[2-[(4-morpholin-4-ylphenyl)amino]pyrimidin-4-yl]phenyl]ethanamide | Human | Show | | |
| JAK2 | JakA | TK | 4bbe | D | n-[4-[2-[(4-morpholin-4-ylphenyl)amino]pyrimidin-4-yl]phenyl]ethanamide | Human | Show | | |
| JAK2 | JakA | TK | 4bbf | A | (2r)-n-[4-[2-[(4-morpholin-4-ylphenyl)amino]pyrimidin-4-yl]phenyl]pyrrolidine-2-carboxamide | Human | Show | | |
| JAK2 | JakA | TK | 4bbf | B | (2r)-n-[4-[2-[(4-morpholin-4-ylphenyl)amino]pyrimidin-4-yl]phenyl]pyrrolidine-2-carboxamide | Human | Show | | |
| JAK2 | JakA | TK | 4bbf | C | (2r)-n-[4-[2-[(4-morpholin-4-ylphenyl)amino]pyrimidin-4-yl]phenyl]pyrrolidine-2-carboxamide | Human | Show | | |
| JAK2 | JakA | TK | 4bbf | D | (2r)-n-[4-[2-[(4-morpholin-4-ylphenyl)amino]pyrimidin-4-yl]phenyl]pyrrolidine-2-carboxamide | Human | Show | | |
| JAK2 | JakA | TK | 4c61 | A | n2-[(1s)-1-(5-fluoropyrimidin-2-yl)ethyl]-7-methyl-n4-(1-methylimidazol-4-yl)thieno[3,2-d]pyrimidine-2,4-diamine | Human | Show | | |
| JAK2 | JakA | TK | 4c61 | B | n2-[(1s)-1-(5-fluoropyrimidin-2-yl)ethyl]-7-methyl-n4-(1-methylimidazol-4-yl)thieno[3,2-d]pyrimidine-2,4-diamine | Human | Show | | |
| JAK2 | JakA | TK | 4c62 | A | n2-[(1s)-1-(5-fluoropyrimidin-2-yl)ethyl]-n4-(1-methylimidazol-4-yl)-6-morpholino-1,3,5-triazine-2,4-diamine | Human | Show | | |
| JAK2 | JakA | TK | 4c62 | B | n2-[(1s)-1-(5-fluoropyrimidin-2-yl)ethyl]-n4-(1-methylimidazol-4-yl)-6-morpholino-1,3,5-triazine-2,4-diamine | Human | Show | | |
| JAK2 | JakA | TK | 4d0w | A | A | 5-(2-aminopyrimidin-4-yl)-2-(5-chloro-2-methylphenyl)-1h-pyrrole-3-carboxamide | Human | Show | |
| JAK2 | JakA | TK | 4d0w | A | B | 5-(2-aminopyrimidin-4-yl)-2-(5-chloro-2-methylphenyl)-1h-pyrrole-3-carboxamide | Human | Show | |
| JAK2 | JakA | TK | 4d0x | A | A | 5-(2-aminopyrimidin-4-yl)-2-[2-chloro-5-(trifluoromethyl)phenyl]-1h-pyrrole-3-carboxamide | Human | Show | |
| JAK2 | JakA | TK | 4d0x | A | B | 5-(2-aminopyrimidin-4-yl)-2-[2-chloro-5-(trifluoromethyl)phenyl]-1h-pyrrole-3-carboxamide | Human | Show | |
| JAK2 | JakA | TK | 4d1s | A | A | 2-(5-chloro-2-methylphenyl)-1-methyl-5-(2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}pyrimidin-4-yl)-1h-pyrrole-3-carboxamide | Human | Show | |
| JAK2 | JakA | TK | 4d1s | A | B | 2-(5-chloro-2-methylphenyl)-1-methyl-5-(2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}pyrimidin-4-yl)-1h-pyrrole-3-carboxamide | Human | Show | |
| JAK2 | JakA | TK | 4e4m | A | 1-[4-methyl-1-(methylsulfonyl)piperidin-4-yl]-1,6-dihydroimidazo[4,5-d]pyrrolo[2,3-b]pyridine | Human | Show | | |
| JAK2 | JakA | TK | 4e4m | B | 1-[4-methyl-1-(methylsulfonyl)piperidin-4-yl]-1,6-dihydroimidazo[4,5-d]pyrrolo[2,3-b]pyridine | Human | Show | | |
| JAK2 | JakA | TK | 4e4m | D | 1-[4-methyl-1-(methylsulfonyl)piperidin-4-yl]-1,6-dihydroimidazo[4,5-d]pyrrolo[2,3-b]pyridine | Human | Show | | |
| JAK2 | JakA | TK | 4e4m | E | 1-[4-methyl-1-(methylsulfonyl)piperidin-4-yl]-1,6-dihydroimidazo[4,5-d]pyrrolo[2,3-b]pyridine | Human | Show | | |
| JAK2 | JakA | TK | 4e6d | A | A | 3-[(3r)-3-(imidazo[4,5-d]pyrrolo[2,3-b]pyridin-1(6h)-yl)piperidin-1-yl]-3-oxopropanenitrile | Human | Show | |
| JAK2 | JakA | TK | 4e6d | A | B | 3-[(3r)-3-(imidazo[4,5-d]pyrrolo[2,3-b]pyridin-1(6h)-yl)piperidin-1-yl]-3-oxopropanenitrile | Human | Show | |
| JAK2 | JakA | TK | 4e6d | B | A | 3-[(3r)-3-(imidazo[4,5-d]pyrrolo[2,3-b]pyridin-1(6h)-yl)piperidin-1-yl]-3-oxopropanenitrile | Human | Show | |
| JAK2 | JakA | TK | 4e6d | B | B | 3-[(3r)-3-(imidazo[4,5-d]pyrrolo[2,3-b]pyridin-1(6h)-yl)piperidin-1-yl]-3-oxopropanenitrile | Human | Show | |
| JAK2 | JakA | TK | 4e6q | A | 1-(1-benzylpiperidin-4-yl)-1,6-dihydroimidazo[4,5-d]pyrrolo[2,3-b]pyridine | Human | Show | | |
| JAK2 | JakA | TK | 4e6q | B | 1-(1-benzylpiperidin-4-yl)-1,6-dihydroimidazo[4,5-d]pyrrolo[2,3-b]pyridine | Human | Show | | |
| JAK2 | JakA | TK | 4f08 | A | 1-(piperidin-4-yl)-1,6-dihydroimidazo[4,5-d]pyrrolo[2,3-b]pyridine | Human | Show | | |
| JAK2 | JakA | TK | 4f08 | B | 1-(piperidin-4-yl)-1,6-dihydroimidazo[4,5-d]pyrrolo[2,3-b]pyridine | Human | Show | | |
| JAK2 | JakA | TK | 4f09 | A | 2-methyl-1-(piperidin-4-yl)-1,6-dihydroimidazo[4,5-d]pyrrolo[2,3-b]pyridine | Human | Show | | |
| JAK2 | JakA | TK | 4gfm | A | A | 2,6-dichloro-n-(2-oxo-2,5-dihydropyridin-4-yl)benzamide | Human | Show | |
| JAK2 | JakA | TK | 4gfm | A | B | 2,6-dichloro-n-(2-oxo-2,5-dihydropyridin-4-yl)benzamide | Human | Show | |
| JAK2 | JakA | TK | 4gmy | A | 2,6-dichloro-n-{2-[(cyclopropylcarbonyl)amino]pyridin-4-yl}benzamide | Human | Show | | |
| JAK2 | JakA | TK | 4hge | A | A | n-[1-(3-chlorophenyl)-3-methyl-1h-pyrazol-5-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide | Human | Show | |
| JAK2 | JakA | TK | 4hge | A | B | n-[1-(3-chlorophenyl)-3-methyl-1h-pyrazol-5-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide | Human | Show | |
| JAK2 | JakA | TK | 4hge | B | A | n-[1-(3-chlorophenyl)-3-methyl-1h-pyrazol-5-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide | Human | Show | |
| JAK2 | JakA | TK | 4hge | B | B | n-[1-(3-chlorophenyl)-3-methyl-1h-pyrazol-5-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide | Human | Show | |
| JAK2 | JakA | TK | 4iva | A | A | trans-4-{2-[(1r)-1-hydroxyethyl]imidazo[4,5-d]pyrrolo[2,3-b]pyridin-1(6h)-yl}cyclohexanecarbonitrile | Human | Show | |
| JAK2 | JakA | TK | 4iva | A | B | trans-4-{2-[(1r)-1-hydroxyethyl]imidazo[4,5-d]pyrrolo[2,3-b]pyridin-1(6h)-yl}cyclohexanecarbonitrile | Human | Show | |
| JAK2 | JakA | TK | 4iva | A | C | trans-4-{2-[(1r)-1-hydroxyethyl]imidazo[4,5-d]pyrrolo[2,3-b]pyridin-1(6h)-yl}cyclohexanecarbonitrile | Human | Show | |
| JAK2 | JakA | TK | 4ji9 | A | n-tert-butyl-3-[(5-methyl-2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}pyrimidin-4-yl)amino]benzenesulfonamide | Human | Show | | |
| JAK2 | JakA | TK | 4ji9 | B | n-tert-butyl-3-[(5-methyl-2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}pyrimidin-4-yl)amino]benzenesulfonamide | Human | Show | |
