PDB-code
Browse kinase entries (page 152 of 282)
First 148 149 150 PreviousLast156 155 154 Next| # | Kinase | Family | Group | PDB | Chain | (Alternate) Model | Orthosteric ligand | Organism | Details | File |
|---|---|---|---|---|---|---|---|---|---|---|
 | JAK2 | JakA | TK | 4jia | A | A | 5-(4-methoxyphenyl)-n-[4-(4-methylpiperazin-1-yl)phenyl][1,2,4]triazolo[1,5-a]pyridin-2-amine | Human | Show |  |
| JAK2 | JakA | TK | 4jia | A | B | 5-(4-methoxyphenyl)-n-[4-(4-methylpiperazin-1-yl)phenyl][1,2,4]triazolo[1,5-a]pyridin-2-amine | Human | Show | |
| JAK2 | JakA | TK | 4p7e | A | n-(5-{4-[(1,1-dioxidothiomorpholin-4-yl)methyl]phenyl}[1,2,4]triazolo[1,5-a]pyridin-2-yl)cyclopropanecarboxamide | Human | Show | | |
| JAK2 | JakA | TK | 4p7e | B | n-(5-{4-[(1,1-dioxidothiomorpholin-4-yl)methyl]phenyl}[1,2,4]triazolo[1,5-a]pyridin-2-yl)cyclopropanecarboxamide | Human | Show | | |
| JAK2 | JakA | TK | 4ytc | A | A | n~3~-phenyl-1-[6-(phenylamino)pyrimidin-4-yl]-1h-1,2,4-triazole-3,5-diamine | Human | Show | |
| JAK2 | JakA | TK | 4ytc | A | B | n~3~-phenyl-1-[6-(phenylamino)pyrimidin-4-yl]-1h-1,2,4-triazole-3,5-diamine | Human | Show | |
| JAK2 | JakA | TK | 4ytf | A | A | n~2~-[2-(5-chloro-1h-pyrrolo[2,3-b]pyridin-3-yl)-5-fluoropyrimidin-4-yl]-n-(2,2,2-trifluoroethyl)-l-alaninamide | Human | Show | |
| JAK2 | JakA | TK | 4ytf | A | B | n~2~-[2-(5-chloro-1h-pyrrolo[2,3-b]pyridin-3-yl)-5-fluoropyrimidin-4-yl]-n-(2,2,2-trifluoroethyl)-l-alaninamide | Human | Show | |
| JAK2 | JakA | TK | 4yth | A | A | n~2~-[2-(5-chloro-1h-pyrrolo[2,3-b]pyridin-3-yl)-5-fluoropyrimidin-4-yl]-2-methyl-n-(2,2,2-trifluoroethyl)-d-alaninamide | Human | Show | |
| JAK2 | JakA | TK | 4yth | A | B | n~2~-[2-(5-chloro-1h-pyrrolo[2,3-b]pyridin-3-yl)-5-fluoropyrimidin-4-yl]-2-methyl-n-(2,2,2-trifluoroethyl)-d-alaninamide | Human | Show | |
| JAK2 | JakA | TK | 4yti | A | A | (2r)-2-methyl-2-[[2-(1h-pyrrolo[2,3-b]pyridin-3-yl)pyrimidin-4-yl]amino]-n-[2,2,2-tris(fluoranyl)ethyl]butanamide | Human | Show | |
| JAK2 | JakA | TK | 4yti | A | B | (2r)-2-methyl-2-[[2-(1h-pyrrolo[2,3-b]pyridin-3-yl)pyrimidin-4-yl]amino]-n-[2,2,2-tris(fluoranyl)ethyl]butanamide | Human | Show | |
| JAK2 | JakA | TK | 4zim | A | A | 3-(3,4-dichlorophenyl)-6-(morpholin-4-ylcarbonyl)-9h-carbazole-1-carboxamide | Human | Show | |
| JAK2 | JakA | TK | 4zim | A | B | 3-(3,4-dichlorophenyl)-6-(morpholin-4-ylcarbonyl)-9h-carbazole-1-carboxamide | Human | Show | |
| JAK2 | JakA | TK | 4zim | B | A | 3-(3,4-dichlorophenyl)-6-(morpholin-4-ylcarbonyl)-9h-carbazole-1-carboxamide | Human | Show | |
| JAK2 | JakA | TK | 4zim | B | B | 3-(3,4-dichlorophenyl)-6-(morpholin-4-ylcarbonyl)-9h-carbazole-1-carboxamide | Human | Show | |
| JAK2 | JakA | TK | 5aep | A | A | 1-(5-chloro-2-methylphenyl)-4-(pyrrolo[2,1-f][1,2,4]triazin-4-yl)-1h-pyrrole-2-carboxamide | Human | Show | |
| JAK2 | JakA | TK | 5aep | A | B | 1-(5-chloro-2-methylphenyl)-4-(pyrrolo[2,1-f][1,2,4]triazin-4-yl)-1h-pyrrole-2-carboxamide | Human | Show | |
| JAK2 | JakA | TK | 5cf4 | A | n,n-dicyclopropyl-6-ethyl-4-[(3-methoxypropyl)amino]-1-methyl-1,6-dihydroimidazo[4,5-d]pyrrolo[2,3-b]pyridine-7-carboxamide | Human | Show | | |
| JAK2 | JakA | TK | 5cf4 | B | n,n-dicyclopropyl-6-ethyl-4-[(3-methoxypropyl)amino]-1-methyl-1,6-dihydroimidazo[4,5-d]pyrrolo[2,3-b]pyridine-7-carboxamide | Human | Show | | |
| JAK2 | JakA | TK | 5cf5 | A | n,n-dicyclopropyl-4-[(4,5-dimethyl-1,3-thiazol-2-yl)amino]-6-ethyl-1-methyl-1,6-dihydroimidazo[4,5-d]pyrrolo[2,3-b]pyridine-7-carboxamide | Human | Show | | |
| JAK2 | JakA | TK | 5cf5 | B | n,n-dicyclopropyl-4-[(4,5-dimethyl-1,3-thiazol-2-yl)amino]-6-ethyl-1-methyl-1,6-dihydroimidazo[4,5-d]pyrrolo[2,3-b]pyridine-7-carboxamide | Human | Show | | |
| JAK2 | JakA | TK | 5cf6 | A | n,n-dicyclopropyl-6-[(2s)-2,3-dihydroxypropyl]-1-methyl-4-(methylamino)-1,6-dihydroimidazo[4,5-d]pyrrolo[2,3-b]pyridine-7-carboxamide | Human | Show | | |
| JAK2 | JakA | TK | 5cf6 | B | n,n-dicyclopropyl-6-[(2s)-2,3-dihydroxypropyl]-1-methyl-4-(methylamino)-1,6-dihydroimidazo[4,5-d]pyrrolo[2,3-b]pyridine-7-carboxamide | Human | Show | | |
| JAK2 | JakA | TK | 5cf8 | A | A | n,n-dicyclopropyl-4-[(1,5-dimethyl-1h-pyrazol-3-yl)amino]-6-ethyl-1-methyl-1,6-dihydroimidazo[4,5-d]pyrrolo[2,3-b]pyridine-7-carboxamide | Human | Show | |
| JAK2 | JakA | TK | 5cf8 | A | B | n,n-dicyclopropyl-4-[(1,5-dimethyl-1h-pyrazol-3-yl)amino]-6-ethyl-1-methyl-1,6-dihydroimidazo[4,5-d]pyrrolo[2,3-b]pyridine-7-carboxamide | Human | Show | |
| JAK2 | JakA | TK | 5cf8 | B | A | n,n-dicyclopropyl-4-[(1,5-dimethyl-1h-pyrazol-3-yl)amino]-6-ethyl-1-methyl-1,6-dihydroimidazo[4,5-d]pyrrolo[2,3-b]pyridine-7-carboxamide | Human | Show | |
| JAK2 | JakA | TK | 5cf8 | B | B | n,n-dicyclopropyl-4-[(1,5-dimethyl-1h-pyrazol-3-yl)amino]-6-ethyl-1-methyl-1,6-dihydroimidazo[4,5-d]pyrrolo[2,3-b]pyridine-7-carboxamide | Human | Show | |
| JAK2 | JakA | TK | 5hez | A | n-tert-butyl-3-[(5-methyl-2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}pyrimidin-4-yl)amino]benzenesulfonamide | Human | Show | | |
| JAK2 | JakA | TK | 5hez | B | n-tert-butyl-3-[(5-methyl-2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}pyrimidin-4-yl)amino]benzenesulfonamide | Human | Show | | |
| JAK2 | JakA | TK | 5hez | C | n-tert-butyl-3-[(5-methyl-2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}pyrimidin-4-yl)amino]benzenesulfonamide | Human | Show | | |
| JAK2 | JakA | TK | 5hez | D | n-tert-butyl-3-[(5-methyl-2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}pyrimidin-4-yl)amino]benzenesulfonamide | Human | Show | | |
| JAK2 | JakA | TK | 5l3a | A | A | ~{n}-(1~{h}-indazol-4-yl)methanesulfonamide | Human | Show | |
| JAK2 | JakA | TK | 5l3a | A | B | ~{n}-(1~{h}-indazol-4-yl)methanesulfonamide | Human | Show | |
| JAK2 | JakA | TK | 5tq3 | A | A | 4-[3-(1h-benzimidazol-2-yl)-1h-indazol-6-yl]-3-ethylphenol | Human | Show | |
| JAK2 | JakA | TK | 5tq3 | A | B | 4-[3-(1h-benzimidazol-2-yl)-1h-indazol-6-yl]-3-ethylphenol | Human | Show | |
| JAK2 | JakA | TK | 5tq3 | B | A | 4-[3-(1h-benzimidazol-2-yl)-1h-indazol-6-yl]-3-ethylphenol | Human | Show | |
| JAK2 | JakA | TK | 5tq3 | B | B | 4-[3-(1h-benzimidazol-2-yl)-1h-indazol-6-yl]-3-ethylphenol | Human | Show | |
| JAK2 | JakA | TK | 5tq4 | A | 6-(2-ethyl-4-hydroxyphenyl)-1h-indazole-3-carboxamide | Human | Show | | |
| JAK2 | JakA | TK | 5tq5 | A | 6-(2-ethyl-4-hydroxyphenyl)-n-(6-methylpyridin-3-yl)-1h-indazole-3-carboxamide | Human | Show | | |
| JAK2 | JakA | TK | 5tq6 | A | {(3r,4r)-4-methyl-3-[methyl(7h-pyrrolo[2,3-d]pyrimidin-4-yl)amino]piperidin-1-yl}(pyrrolidin-1-yl)methanone | Human | Show | | |
| JAK2 | JakA | TK | 5tq6 | B | {(3r,4r)-4-methyl-3-[methyl(7h-pyrrolo[2,3-d]pyrimidin-4-yl)amino]piperidin-1-yl}(pyrrolidin-1-yl)methanone | Human | Show | | |
| JAK2 | JakA | TK | 5tq7 | A | {(3r,4r)-4-methyl-3-[methyl(7h-pyrrolo[2,3-d]pyrimidin-4-yl)amino]piperidin-1-yl}[(3r)-3-(phenylsulfonyl)pyrrolidin-1-yl]methanone | Human | Show | | |
| JAK2 | JakA | TK | 5tq7 | B | {(3r,4r)-4-methyl-3-[methyl(7h-pyrrolo[2,3-d]pyrimidin-4-yl)amino]piperidin-1-yl}[(3r)-3-(phenylsulfonyl)pyrrolidin-1-yl]methanone | Human | Show | | |
| JAK2 | JakA | TK | 5tq8 | A | {2-[6-(2-ethyl-5-fluoro-4-hydroxyphenyl)-2h-indazol-3-yl]-3,4,6,7-tetrahydro-5h-imidazo[4,5-c]pyridin-5-yl}[5-(piperidin-1-yl)pyrazin-2-yl]methanone | Human | Show | | |
| JAK2 | JakA | TK | 5usy | A | A | 4-({5-amino-1-[(2,6-difluorophenyl)carbonyl]-1h-1,2,4-triazol-3-yl}amino)benzenesulfonamide | Human | Show | |
| JAK2 | JakA | TK | 5usy | A | B | 4-({5-amino-1-[(2,6-difluorophenyl)carbonyl]-1h-1,2,4-triazol-3-yl}amino)benzenesulfonamide | Human | Show | |
| JAK2 | JakA | TK | 5usy | B | A | 4-({5-amino-1-[(2,6-difluorophenyl)carbonyl]-1h-1,2,4-triazol-3-yl}amino)benzenesulfonamide | Human | Show | |
| JAK2 | JakA | TK | 5usy | B | B | 4-({5-amino-1-[(2,6-difluorophenyl)carbonyl]-1h-1,2,4-triazol-3-yl}amino)benzenesulfonamide | Human | Show | |
| JAK2 | JakA | TK | 5wev | A | A | n-[2-(2,6-dichlorophenyl)-1h-imidazo[4,5-c]pyridin-4-yl]cyclopropanecarboxamide | Human | Show | |
