PDB-code
Browse kinase entries (page 156 of 282)
First 152 153 154 PreviousLast160 159 158 Next| # | Kinase | Family | Group | PDB | Chain | (Alternate) Model | Orthosteric ligand | Organism | Details | File |
|---|---|---|---|---|---|---|---|---|---|---|
 | JAK3 | JakA | TK | 3zc6 | C | B | n-[(2r)-1-(3-cyanoazetidin-1-yl)-1-oxidanylidene-propan-2-yl]-2-(6-fluoranyl-1-methyl-indazol-3-yl)-5h-pyrrolo[2,3-b]pyrazine-7-carboxamide | Human | Show |  |
| JAK3 | JakA | TK | 3zc6 | D | A | n-[(2r)-1-(3-cyanoazetidin-1-yl)-1-oxidanylidene-propan-2-yl]-2-(6-fluoranyl-1-methyl-indazol-3-yl)-5h-pyrrolo[2,3-b]pyrazine-7-carboxamide | Human | Show | |
| JAK3 | JakA | TK | 3zc6 | D | B | n-[(2r)-1-(3-cyanoazetidin-1-yl)-1-oxidanylidene-propan-2-yl]-2-(6-fluoranyl-1-methyl-indazol-3-yl)-5h-pyrrolo[2,3-b]pyrazine-7-carboxamide | Human | Show | |
| JAK3 | JakA | TK | 3zep | A | A | 2-[[(3r)-3-acetamido-2,3-dihydro-1h-inden-5-yl]oxy]-n-[(1s)-1-cyclopropylethyl]-5h-pyrrolo[2,3-b]pyrazine-7-carboxamide | Human | Show | |
| JAK3 | JakA | TK | 3zep | A | B | 2-[[(3r)-3-acetamido-2,3-dihydro-1h-inden-5-yl]oxy]-n-[(1s)-1-cyclopropylethyl]-5h-pyrrolo[2,3-b]pyrazine-7-carboxamide | Human | Show | |
| JAK3 | JakA | TK | 3zep | B | A | 2-[[(3r)-3-acetamido-2,3-dihydro-1h-inden-5-yl]oxy]-n-[(1s)-1-cyclopropylethyl]-5h-pyrrolo[2,3-b]pyrazine-7-carboxamide | Human | Show | |
| JAK3 | JakA | TK | 3zep | B | B | 2-[[(3r)-3-acetamido-2,3-dihydro-1h-inden-5-yl]oxy]-n-[(1s)-1-cyclopropylethyl]-5h-pyrrolo[2,3-b]pyrazine-7-carboxamide | Human | Show | |
| JAK3 | JakA | TK | 3zep | C | A | 2-[[(3r)-3-acetamido-2,3-dihydro-1h-inden-5-yl]oxy]-n-[(1s)-1-cyclopropylethyl]-5h-pyrrolo[2,3-b]pyrazine-7-carboxamide | Human | Show | |
| JAK3 | JakA | TK | 3zep | C | B | 2-[[(3r)-3-acetamido-2,3-dihydro-1h-inden-5-yl]oxy]-n-[(1s)-1-cyclopropylethyl]-5h-pyrrolo[2,3-b]pyrazine-7-carboxamide | Human | Show | |
| JAK3 | JakA | TK | 3zep | D | A | 2-[[(3r)-3-acetamido-2,3-dihydro-1h-inden-5-yl]oxy]-n-[(1s)-1-cyclopropylethyl]-5h-pyrrolo[2,3-b]pyrazine-7-carboxamide | Human | Show | |
| JAK3 | JakA | TK | 3zep | D | B | 2-[[(3r)-3-acetamido-2,3-dihydro-1h-inden-5-yl]oxy]-n-[(1s)-1-cyclopropylethyl]-5h-pyrrolo[2,3-b]pyrazine-7-carboxamide | Human | Show | |
| JAK3 | JakA | TK | 4hvd | A | 2-cyclopropyl-n-[(2s)-3,3-dimethylbutan-2-yl]-5h-pyrrolo[2,3-b]pyrazine-7-carboxamide | Human | Show | | |
| JAK3 | JakA | TK | 4hvg | A | 2-cyclopropyl-n-[(2s)-3-hydroxy-3-methylbutan-2-yl]-5h-pyrrolo[2,3-b]pyrazine-7-carboxamide | Human | Show | | |
| JAK3 | JakA | TK | 4hvh | A | 2-cyclopropyl-n-[(2r)-3-hydroxy-3-methylbutan-2-yl]-5h-pyrrolo[2,3-b]pyrazine-7-carboxamide | Human | Show | | |
| JAK3 | JakA | TK | 4hvi | A | 2-cyclopropyl-n-[(2r)-1-oxo-1-(piperidin-1-yl)propan-2-yl]-5h-pyrrolo[2,3-b]pyrazine-7-carboxamide | Human | Show | | |
| JAK3 | JakA | TK | 4i6q | A | n-[(1s)-1-cyclopropylethyl]-2-phenoxy-5h-pyrrolo[2,3-b]pyrazine-7-carboxamide | Human | Show | | |
| JAK3 | JakA | TK | 4qps | A | A | n-{1-[6-(phenylamino)pyrazin-2-yl]-1h-benzimidazol-6-yl}prop-2-enamide | Human | Show | |
| JAK3 | JakA | TK | 4qps | A | B | n-{1-[6-(phenylamino)pyrazin-2-yl]-1h-benzimidazol-6-yl}prop-2-enamide | Human | Show | |
| JAK3 | JakA | TK | 4qps | C | A | n-{1-[6-(phenylamino)pyrazin-2-yl]-1h-benzimidazol-6-yl}prop-2-enamide | Human | Show | |
| JAK3 | JakA | TK | 4qps | C | B | n-{1-[6-(phenylamino)pyrazin-2-yl]-1h-benzimidazol-6-yl}prop-2-enamide | Human | Show | |
| JAK3 | JakA | TK | 4qt1 | A | 1-{(3s)-1-[(2-methylpropyl)sulfonyl]piperidin-3-yl}-3-(5h-pyrrolo[2,3-b]pyrazin-2-yl)urea | Human | Show | | |
| JAK3 | JakA | TK | 4rio | A | 4-{[(1r,2s)-2-fluoro-2-methylcyclopentyl]amino}pyrrolo[1,2-b]pyridazine-3-carboxamide | Human | Show | | |
| JAK3 | JakA | TK | 4v0g | A | A | n-[3-(2-{3-amino-6-[1-(1-methylpiperidin-4-yl)-1h-pyrazol-4-yl]pyrazin-2-yl}-1h-benzimidazol-1-yl)phenyl]propanamide | Human | Show | |
| JAK3 | JakA | TK | 4v0g | A | B | n-[3-(2-{3-amino-6-[1-(1-methylpiperidin-4-yl)-1h-pyrazol-4-yl]pyrazin-2-yl}-1h-benzimidazol-1-yl)phenyl]propanamide | Human | Show | |
| JAK3 | JakA | TK | 4v0g | B | A | n-[3-(2-{3-amino-6-[1-(1-methylpiperidin-4-yl)-1h-pyrazol-4-yl]pyrazin-2-yl}-1h-benzimidazol-1-yl)phenyl]propanamide | Human | Show | |
| JAK3 | JakA | TK | 4v0g | B | B | n-[3-(2-{3-amino-6-[1-(1-methylpiperidin-4-yl)-1h-pyrazol-4-yl]pyrazin-2-yl}-1h-benzimidazol-1-yl)phenyl]propanamide | Human | Show | |
| JAK3 | JakA | TK | 4z16 | A | n-(3-{[(5-chloro-2-{[2-methoxy-4-(4-methylpiperazin-1-yl)phenyl]amino}pyrimidin-4-yl)amino]methyl}phenyl)prop-2-enamide | Human | Show | | |
| JAK3 | JakA | TK | 4z16 | B | n-(3-{[(5-chloro-2-{[2-methoxy-4-(4-methylpiperazin-1-yl)phenyl]amino}pyrimidin-4-yl)amino]methyl}phenyl)prop-2-enamide | Human | Show | | |
| JAK3 | JakA | TK | 4z16 | C | n-(3-{[(5-chloro-2-{[2-methoxy-4-(4-methylpiperazin-1-yl)phenyl]amino}pyrimidin-4-yl)amino]methyl}phenyl)prop-2-enamide | Human | Show | | |
| JAK3 | JakA | TK | 4z16 | D | n-(3-{[(5-chloro-2-{[2-methoxy-4-(4-methylpiperazin-1-yl)phenyl]amino}pyrimidin-4-yl)amino]methyl}phenyl)prop-2-enamide | Human | Show | | |
| JAK3 | JakA | TK | 5lwm | A | A | 2-cyano-3-[5-(3-cyclohexyl-3,5,8,10-tetrazatricyclo[7.3.0.0^{2,6}]dodeca-1,4,6,8,11-pentaen-4-yl)furan-2-yl]-~{n},~{n}-dimethyl-prop-2-enamide | Human | Show | |
| JAK3 | JakA | TK | 5lwm | A | B | 2-cyano-3-[5-(3-cyclohexyl-3,5,8,10-tetrazatricyclo[7.3.0.0^{2,6}]dodeca-1,4,6,8,11-pentaen-4-yl)furan-2-yl]-~{n},~{n}-dimethyl-prop-2-enamide | Human | Show | |
| JAK3 | JakA | TK | 5lwn | A | A | (~{z})-2-cyano-~{n},~{n}-dimethyl-3-[5-[3-[(1~{s},2~{r})-2-methylcyclohexyl]-3,5,8,10-tetrazatricyclo[7.3.0.0^{2,6}]dodeca-1,4,6,8,11-pentaen-4-yl]furan-2-yl]prop-2-enamide | Human | Show | |
| JAK3 | JakA | TK | 5lwn | A | B | (2~{s})-2-cyano-~{n},~{n}-dimethyl-3-[5-[3-[(1~{s},2~{r})-2-methylcyclohexyl]-3,5,8,10-tetrazatricyclo[7.3.0.0^{2,6}]dodeca-1,4,6,8,11-pentaen-4-yl]furan-2-yl]propanamide | Human | Show | |
| JAK3 | JakA | TK | 5toz | A | 1-{(2s,5r)-2-methyl-5-[(7h-pyrrolo[2,3-d]pyrimidin-4-yl)amino]piperidin-1-yl}propan-1-one | Human | Show | | |
| JAK3 | JakA | TK | 5tts | A | 1-{(3r)-3-[(7h-pyrrolo[2,3-d]pyrimidin-4-yl)amino]piperidin-1-yl}propan-1-one | Human | Show | | |
| JAK3 | JakA | TK | 5ttu | A | A | 1-[(3ar,7ar)-1-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)octahydro-6h-pyrrolo[2,3-c]pyridin-6-yl]propan-1-one | Human | Show | |
| JAK3 | JakA | TK | 5ttu | A | B | 1-[(3ar,7ar)-1-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)octahydro-6h-pyrrolo[2,3-c]pyridin-6-yl]propan-1-one | Human | Show | |
| JAK3 | JakA | TK | 5ttv | A | A | n-[3-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)phenyl]propanamide | Human | Show | |
| JAK3 | JakA | TK | 5ttv | A | B | n-[3-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)phenyl]propanamide | Human | Show | |
| JAK3 | JakA | TK | 5vo6 | A | 4-{[(1r,3s)-3-amino-2,2,3-trimethylcyclopentyl]amino}-6-phenylpyrrolo[1,2-b]pyridazine-3-carboxamide | Human | Show | | |
| JAK3 | JakA | TK | 5w86 | A | A | 4-(benzylamino)-6-({4-[(1-methylpiperidin-4-yl)carbamoyl]phenyl}amino)pyridine-3-carboxamide | Human | Show | |
| JAK3 | JakA | TK | 5w86 | B | A | 4-(benzylamino)-6-({4-[(1-methylpiperidin-4-yl)carbamoyl]phenyl}amino)pyridine-3-carboxamide | Human | Show | |
| JAK3 | JakA | TK | 5w86 | C | A | 4-(benzylamino)-6-({4-[(1-methylpiperidin-4-yl)carbamoyl]phenyl}amino)pyridine-3-carboxamide | Human | Show | |
| JAK3 | JakA | TK | 5w86 | D | A | 4-(benzylamino)-6-({4-[(1-methylpiperidin-4-yl)carbamoyl]phenyl}amino)pyridine-3-carboxamide | Human | Show | |
| JAK3 | JakA | TK | 5wfj | A | 4-({[3-(propanoylamino)phenyl]methyl}amino)pyrrolo[1,2-b]pyridazine-3-carboxamide | Human | Show | | |
| JAK3 | JakA | TK | 6aak | A | 4-[[(1s,3r)-5-oxidanyl-2-adamantyl]amino]-1h-pyrrolo[2,3-b]pyridine-5-carboxamide | Human | Show | | |
| JAK3 | JakA | TK | 6aak | B | 4-[[(1s,3r)-5-oxidanyl-2-adamantyl]amino]-1h-pyrrolo[2,3-b]pyridine-5-carboxamide | Human | Show | | |
| JAK3 | JakA | TK | 6aak | C | 4-[[(1s,3r)-5-oxidanyl-2-adamantyl]amino]-1h-pyrrolo[2,3-b]pyridine-5-carboxamide | Human | Show | | |
| JAK3 | JakA | TK | 6aak | D | 4-[[(1s,3r)-5-oxidanyl-2-adamantyl]amino]-1h-pyrrolo[2,3-b]pyridine-5-carboxamide | Human | Show | |
