Version: 3.2
Updated: 05-Nov-2025

Browse kinase entries (page 211 of 282)

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#KinaseFamilyGroupPDBChain(Alternate) Model Orthosteric ligandOrganism DetailsFile
NTRK1 (TRKA)TrkTK6nptA4-tert-butyl-n-(1,3-diphenyl-1h-pyrazol-5-yl)benzamideHumanShow
NTRK1 (TRKA)TrkTK6nspAAn-(8-methyl-2-phenylimidazo[1,2-a]pyridin-3-yl)-2-(3-oxo-2,3-dihydro-4h-1,4-benzothiazin-4-yl)acetamideHumanShow
NTRK1 (TRKA)TrkTK6nspABn-(8-methyl-2-phenylimidazo[1,2-a]pyridin-3-yl)-2-(3-oxo-2,3-dihydro-4h-1,4-benzothiazin-4-yl)acetamideHumanShow
NTRK1 (TRKA)TrkTK6nssAAn-(8-methyl-2-phenylimidazo[1,2-a]pyrazin-3-yl)-2-(10h-phenoxazin-10-yl)acetamideHumanShow
NTRK1 (TRKA)TrkTK6nssABn-(8-methyl-2-phenylimidazo[1,2-a]pyrazin-3-yl)-2-(10h-phenoxazin-10-yl)acetamideHumanShow
NTRK1 (TRKA)TrkTK6pl1AAn-(5-{[(7-methyl-4-oxo-4h-pyrido[1,2-a]pyrimidin-2-yl)methyl]sulfanyl}-1,3,4-thiadiazol-2-yl)-n'-[3-(trifluoromethyl)phenyl]ureaHumanShow
NTRK1 (TRKA)TrkTK6pl1ABn-(5-{[(7-methyl-4-oxo-4h-pyrido[1,2-a]pyrimidin-2-yl)methyl]sulfanyl}-1,3,4-thiadiazol-2-yl)-n'-[3-(trifluoromethyl)phenyl]ureaHumanShow
NTRK1 (TRKA)TrkTK6pl2An-(3-tert-butyl-1-phenyl-1h-pyrazol-5-yl)-2-{[1-(4-hydroxyphenyl)-1h-tetrazol-5-yl]sulfanyl}acetamideHumanShow
NTRK1 (TRKA)TrkTK6pl3AA2-[(3-tert-butyl-1-phenyl-1h-pyrazol-5-yl)amino]-2-oxoethyl 4-(1h-tetrazol-1-yl)benzoateHumanShow
NTRK1 (TRKA)TrkTK6pl3AB2-[(3-tert-butyl-1-phenyl-1h-pyrazol-5-yl)amino]-2-oxoethyl 4-(1h-tetrazol-1-yl)benzoateHumanShow
NTRK1 (TRKA)TrkTK6pl4AAn-{[5-(methoxymethyl)-2-(trifluoromethoxy)phenyl]methyl}-n'-(8-methyl-2-phenylimidazo[1,2-a]pyrazin-3-yl)ureaHumanShow
NTRK1 (TRKA)TrkTK6pl4ABn-{[5-(methoxymethyl)-2-(trifluoromethoxy)phenyl]methyl}-n'-(8-methyl-2-phenylimidazo[1,2-a]pyrazin-3-yl)ureaHumanShow
NTRK1 (TRKA)TrkTK6pmaAn-[2-chloro-5-(trifluoromethyl)phenyl]-2-[1-(4-methoxyphenyl)-4-oxo-1,4-dihydro-5h-pyrazolo[3,4-d]pyrimidin-5-yl]acetamideHumanShow
NTRK1 (TRKA)TrkTK6pmbA2-[5,7-dimethyl-2-(pyridin-3-yl)[1,2,4]triazolo[1,5-a]pyrimidin-6-yl]-n-[3-(trifluoromethyl)phenyl]acetamideHumanShow
NTRK1 (TRKA)TrkTK6pmcAn-(6-{[(5-chloro-2-methoxyphenyl)carbamoyl]amino}-1,3-benzothiazol-2-yl)benzamideHumanShow
NTRK1 (TRKA)TrkTK6pmeAAn-[2,4-bis(morpholin-4-yl)phenyl]-3-phenoxybenzamideHumanShow
NTRK1 (TRKA)TrkTK6pmeABn-[2,4-bis(morpholin-4-yl)phenyl]-3-phenoxybenzamideHumanShow
NTRK1 (TRKA)TrkTK6pmeBAn-[2,4-bis(morpholin-4-yl)phenyl]-3-phenoxybenzamideHumanShow
NTRK1 (TRKA)TrkTK6pmeBBn-[2,4-bis(morpholin-4-yl)phenyl]-3-phenoxybenzamideHumanShow
NTRK1 (TRKA)TrkTK6pmeCAn-[2,4-bis(morpholin-4-yl)phenyl]-3-phenoxybenzamideHumanShow
NTRK1 (TRKA)TrkTK6pmeCBn-[2,4-bis(morpholin-4-yl)phenyl]-3-phenoxybenzamideHumanShow
NTRK1 (TRKA)TrkTK7vkmAA-HumanShow
NTRK1 (TRKA)TrkTK7vkmAB-HumanShow
NTRK1 (TRKA)TrkTK7vknAArepotrectinibHumanShow
NTRK1 (TRKA)TrkTK7vknABrepotrectinibHumanShow
NTRK1 (TRKA)TrkTK7vkoArepotrectinibHumanShow
NTRK1 (TRKA)TrkTK7xafA4^6,14-dimethyl-n-(3-(4-methyl-1h-imidazol-1-yl)-5-(trifluoromethyl)phenyl)-10-oxo-5-oxa-11,14-diaza-1(3,6)-imidazo[1,2-b]pyridazina-4(1,3)-benzenacyclo-tetradecaphan-2-yne-45-carboxamideHumanShow
NTRK1 (TRKA)TrkTK7xbiAA4-[[2-fluoranyl-5-(trifluoromethyl)phenyl]carbamoylamino]-~{n}-[3-(1-methylpyrazol-4-yl)-1~{h}-indazol-5-yl]-2-(trifluoromethyl)benzamideHumanShow
NTRK1 (TRKA)TrkTK7xbiAB4-[[2-fluoranyl-5-(trifluoromethyl)phenyl]carbamoylamino]-~{n}-[3-(1-methylpyrazol-4-yl)-1~{h}-indazol-5-yl]-2-(trifluoromethyl)benzamideHumanShow
NTRK1 (TRKA)TrkTK8j5wAn-(3-cyclopropyl-5-((4-methylpiperazin-1-yl)methyl)phenyl)-4^6-methyl-14-oxo-5-oxa-13-aza-1(3,6)-imidazo[1,2-b]pyridazina-4(1,3)-benzenacyclotetradecaphan-2-yne-4^5-carboxamideHumanShow
NTRK1 (TRKA)TrkTK8j5xAn-(3-cyclopropyl-5-((4-methylpiperazin-1-yl)methyl)phenyl)-4^6-methyl-14-oxo-5-oxa-13-aza-1(3,6)-imidazo[1,2-b]pyridazina-4(1,3)-benzenacyclotetradecaphan-2-yne-4^5-carboxamideHumanShow
NTRK1 (TRKA)TrkTK8j61A4^6-methyl-n-(3-(4-methyl-1h-imidazol-1-yl)-5-(trifluoromethyl)phenyl)-14-oxo-5-oxa-13-aza-1(3,6)-imidazo[1,2-b]pyridazina-4(1,3)-benzenacyclotetradecaphan-2-yne-4^5-carboxamideHumanShow
NTRK1 (TRKA)TrkTK8j63A4^6-methyl-n-(3-(4-methyl-1h-imidazol-1-yl)-5-(trifluoromethyl)phenyl)-11-oxo-5-oxa-10,14-diaza-1(3,6)-imidazo[1,2-b]pyridazina-4(1,3)-benzenacyclotetradecaphan-2-yne-4^5-carboxamideHumanShow
NTRK2 (TRKB)TrkTK4aszA-HumanShow
NTRK2 (TRKB)TrkTK4at3A(5z)-5-(carbamoylimino)-3-[(5r)-6,7,8,9-tetrahydro-5h-benzo[7]annulen-5-ylsulfanyl]-2,5-dihydroisothiazole-4-carboxamideHumanShow
NTRK2 (TRKB)TrkTK4at4A1-[4-(4-aminothieno[2,3-d]pyrimidin-5-yl)phenyl]-3-[2-fluoro-5-(trifluoromethyl)phenyl]ureaHumanShow
NTRK2 (TRKB)TrkTK4at5A5-{3-methoxy-4-[(4-methoxybenzyl)oxy]benzyl}pyrimidine-2,4-diamineHumanShow
NTRK3 (TRKC)TrkTK3v5qA1-(3-{[(3z)-2-oxo-3-(1h-pyrrol-2-ylmethylidene)-2,3-dihydro-1h-indol-6-yl]amino}phenyl)-3-[3-(trifluoromethyl)phenyl]ureaHumanShow
NTRK3 (TRKC)TrkTK3v5qB1-(3-{[(3z)-2-oxo-3-(1h-pyrrol-2-ylmethylidene)-2,3-dihydro-1h-indol-6-yl]amino}phenyl)-3-[3-(trifluoromethyl)phenyl]ureaHumanShow
NTRK3 (TRKC)TrkTK4ymjAA4-[6-(benzylamino)imidazo[1,2-b]pyridazin-3-yl]benzonitrileHumanShow
NTRK3 (TRKC)TrkTK4ymjAB4-[6-(benzylamino)imidazo[1,2-b]pyridazin-3-yl]benzonitrileHumanShow
NTRK3 (TRKC)TrkTK4ymjBA4-[6-(benzylamino)imidazo[1,2-b]pyridazin-3-yl]benzonitrileHumanShow
NTRK3 (TRKC)TrkTK4ymjBB4-[6-(benzylamino)imidazo[1,2-b]pyridazin-3-yl]benzonitrileHumanShow
NTRK3 (TRKC)TrkTK6kzcA3-(2-imidazo[1,2-a]pyrazin-3-ylethynyl)-2-methyl-~{n}-[3-(4-methylpiperazin-1-yl)-5-(trifluoromethyl)phenyl]benzamideHumanShow
NTRK3 (TRKC)TrkTK6kzdA3-[2-[6-(4-aminophenyl)imidazo[1,2-a]pyrazin-3-yl]ethynyl]-2-methyl-~{n}-[3-(4-methylpiperazin-1-yl)-5-propan-2-yl-phenyl]benzamideHumanShow
OXSR1 (OSR1)STE20STE2vwiAAphosphoaminophosphonic acid-adenylate esterHumanShow
OXSR1 (OSR1)STE20STE2vwiABphosphoaminophosphonic acid-adenylate esterHumanShow
OXSR1 (OSR1)STE20STE2vwiBAphosphoaminophosphonic acid-adenylate esterHumanShow
OXSR1 (OSR1)STE20STE2vwiBBphosphoaminophosphonic acid-adenylate esterHumanShow
OXSR1 (OSR1)STE20STE2vwiCAphosphoaminophosphonic acid-adenylate esterHumanShow
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