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Updated: 01-Nov-2025

Browse kinase entries (page 224 of 282)

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#KinaseFamilyGroupPDBChain(Alternate) Model Orthosteric ligandOrganism DetailsFile
Pik3cd (p110d)PIKAtypical5t28A3-(benzotriazol-1-yl)-5-[1-methyl-5-(1-phenylcyclopropyl)-1,2,4-triazol-3-yl]pyrazin-2-amineMouseShow
Pik3cd (p110d)PIKAtypical5t2bA5-[1-methyl-5-(1-phenylcyclopropyl)-1,2,4-triazol-3-yl]-3-(1~{h}-pyrazol-4-yl)pyrazin-2-amineMouseShow
Pik3cd (p110d)PIKAtypical5t2dA4-[3-azanyl-6-[1-methyl-5-(1-phenylcyclopropyl)-1,2,4-triazol-3-yl]pyrazin-2-yl]-~{n},~{n}-dimethyl-pyrazole-1-sulfonamideMouseShow
Pik3cd (p110d)PIKAtypical5t2gA4-[3-azanyl-6-[1-methyl-5-(1-phenylcyclopropyl)-1,2,4-triazol-3-yl]pyrazin-2-yl]pyrazole-1-carboxamideMouseShow
Pik3cd (p110d)PIKAtypical5t2iAA1-[3-azanyl-6-[1-methyl-5-(1-phenylcyclopropyl)-1,2,4-triazol-3-yl]pyrazin-2-yl]pyrazole-4-carboxamideMouseShow
Pik3cd (p110d)PIKAtypical5t2iAB1-[3-azanyl-6-[1-methyl-5-(1-phenylcyclopropyl)-1,2,4-triazol-3-yl]pyrazin-2-yl]pyrazole-4-carboxamideMouseShow
Pik3cd (p110d)PIKAtypical5t2lAA1-[3-azanyl-6-[1-methyl-5-(1-phenylcyclopropyl)-1,2,4-triazol-3-yl]pyrazin-2-yl]pyrazole-3-carboxamideMouseShow
Pik3cd (p110d)PIKAtypical5t2lAB1-[3-azanyl-6-[1-methyl-5-(1-phenylcyclopropyl)-1,2,4-triazol-3-yl]pyrazin-2-yl]pyrazole-3-carboxamideMouseShow
Pik3cd (p110d)PIKAtypical5t2mA4-[3-azanyl-6-[1-methyl-5-(1-phenylcyclopropyl)-1,2,4-triazol-3-yl]pyrazin-2-yl]benzamideMouseShow
Pik3cd (p110d)PIKAtypical5t7fA2,4-bis(azanyl)-6-[[(1~{s})-1-[5-chloranyl-3-(5-fluoranyl-4-methyl-pyridin-3-yl)-4-oxidanylidene-quinazolin-2-yl]ethyl]amino]pyrimidine-5-carbonitrileMouseShow
Pik3cd (p110d)PIKAtypical5t7fB2,4-bis(azanyl)-6-[[(1~{s})-1-[5-chloranyl-3-(5-fluoranyl-4-methyl-pyridin-3-yl)-4-oxidanylidene-quinazolin-2-yl]ethyl]amino]pyrimidine-5-carbonitrileMouseShow
Pik3cd (p110d)PIKAtypical5t8iAA2,4-diamino-6-{[(s)-[5-chloro-8-fluoro-4-oxo-3-(pyridin-3-yl)-3,4-dihydroquinazolin-2-yl](cyclopropyl)methyl]amino}pyrimidine-5-carbonitrileMouseShow
Pik3cd (p110d)PIKAtypical5t8iAB2,4-diamino-6-{[(s)-[5-chloro-8-fluoro-4-oxo-3-(pyridin-3-yl)-3,4-dihydroquinazolin-2-yl](cyclopropyl)methyl]amino}pyrimidine-5-carbonitrileMouseShow
Pik3cd (p110d)PIKAtypical6dgtA4-[1-(5,8-difluoroquinolin-4-yl)-2-methyl-4-(4h-1,2,4-triazol-3-yl)-1h-benzimidazol-6-yl]-3-fluoropyridin-2-amineMouseShow
Pik3cd (p110d)PIKAtypical6eyzA2-methoxy-5-[4-[5-[(4-propan-2-ylpiperazin-1-yl)methyl]-1,3-oxazol-2-yl]-2~{h}-indazol-6-yl]pyridine-3-carboxylic acidMouseShow
Pik3cd (p110d)PIKAtypical6ez6Amethyl 2-methoxy-5-[4-[5-[(4-propan-2-ylpiperazin-1-yl)methyl]-1,3-oxazol-2-yl]-2~{h}-indazol-6-yl]pyridine-3-carboxylateMouseShow
Pik3cd (p110d)PIKAtypical6ftnAA~{n}-[5-[2-[(1~{s})-1-cyclopropylethyl]-7-methyl-1-oxidanylidene-3~{h}-isoindol-5-yl]-4-methyl-1,3-thiazol-2-yl]ethanamideMouseShow
Pik3cd (p110d)PIKAtypical6ftnAB~{n}-[5-[2-[(1~{s})-1-cyclopropylethyl]-7-methyl-1-oxidanylidene-3~{h}-isoindol-5-yl]-4-methyl-1,3-thiazol-2-yl]ethanamideMouseShow
Pik3cd (p110d)PIKAtypical6gy0A~{n}-[4-methyl-5-(1-oxidanylidene-7-sulfamoyl-isoindol-5-yl)-1,3-thiazol-2-yl]ethanamideMouseShow
Pik3cd (p110d)PIKAtypical6hi1A3-(6-morpholin-4-ylpyridin-2-yl)phenolMouseShow
Pik3cd (p110d)PIKAtypical6hi2A3-[6-[(1~{s},6~{r})-3-oxabicyclo[4.1.0]heptan-6-yl]pyridin-2-yl]phenolMouseShow
Pik3cd (p110d)PIKAtypical6hi9AA3-[6-(oxan-4-yl)pyridin-2-yl]phenolMouseShow
Pik3cd (p110d)PIKAtypical6hi9AB3-[6-(oxan-4-yl)pyridin-2-yl]phenolMouseShow
Pik3cd (p110d)PIKAtypical6mulAA1-{1-[8-(1-ethyl-5-methyl-1h-pyrazol-4-yl)-9-methyl-9h-purin-6-yl]piperidin-4-yl}-1,3-dihydro-2h-imidazo[4,5-b]pyridin-2-oneMouseShow
Pik3cd (p110d)PIKAtypical6mulAB1-{1-[8-(1-ethyl-5-methyl-1h-pyrazol-4-yl)-9-methyl-9h-purin-6-yl]piperidin-4-yl}-1,3-dihydro-2h-imidazo[4,5-b]pyridin-2-oneMouseShow
Pik3cd (p110d)PIKAtypical6mulBA1-{1-[8-(1-ethyl-5-methyl-1h-pyrazol-4-yl)-9-methyl-9h-purin-6-yl]piperidin-4-yl}-1,3-dihydro-2h-imidazo[4,5-b]pyridin-2-oneMouseShow
Pik3cd (p110d)PIKAtypical6mulBB1-{1-[8-(1-ethyl-5-methyl-1h-pyrazol-4-yl)-9-methyl-9h-purin-6-yl]piperidin-4-yl}-1,3-dihydro-2h-imidazo[4,5-b]pyridin-2-oneMouseShow
Pik3cd (p110d)PIKAtypical6mumAA[(3s)-3-{[8-(1-ethyl-5-methyl-1h-pyrazol-4-yl)-9-methyl-9h-purin-6-yl]oxy}pyrrolidin-1-yl](oxan-4-yl)methanoneMouseShow
Pik3cd (p110d)PIKAtypical6mumAB[(3s)-3-{[8-(1-ethyl-5-methyl-1h-pyrazol-4-yl)-9-methyl-9h-purin-6-yl]oxy}pyrrolidin-1-yl](oxan-4-yl)methanoneMouseShow
Pik3cd (p110d)PIKAtypical6mumBA[(3s)-3-{[8-(1-ethyl-5-methyl-1h-pyrazol-4-yl)-9-methyl-9h-purin-6-yl]oxy}pyrrolidin-1-yl](oxan-4-yl)methanoneMouseShow
Pik3cd (p110d)PIKAtypical6mumBB[(3s)-3-{[8-(1-ethyl-5-methyl-1h-pyrazol-4-yl)-9-methyl-9h-purin-6-yl]oxy}pyrrolidin-1-yl](oxan-4-yl)methanoneMouseShow
Pik3cd (p110d)PIKAtypical6q6yA~{n}-(2-chloranyl-5-phenyl-pyridin-3-yl)benzenesulfonamideMouseShow
Pik3cd (p110d)PIKAtypical6q73A~{n}-[2-chloranyl-5-(3,6-dihydro-2~{h}-pyran-4-yl)pyridin-3-yl]methanesulfonamideMouseShow
Pik3cd (p110d)PIKAtypical6q74A~{n}-[5-(3,6-dihydro-2~{h}-pyran-4-yl)-2-methoxy-pyridin-3-yl]-2-methyl-1-(phenylmethyl)imidazole-4-sulfonamideMouseShow
Pik3cd (p110d)PIKAtypical6tnrAA~{n}-[2-methoxy-5-[7-[2-[4-(2-oxidanylpropan-2-yl)piperidin-1-yl]ethoxy]-1,3-dihydro-2-benzofuran-5-yl]pyridin-3-yl]methanesulfonamideMouseShow
Pik3cd (p110d)PIKAtypical6tnrAB~{n}-[2-methoxy-5-[7-[2-[4-(2-oxidanylpropan-2-yl)piperidin-1-yl]ethoxy]-1,3-dihydro-2-benzofuran-5-yl]pyridin-3-yl]methanesulfonamideMouseShow
Pik3cd (p110d)PIKAtypical6tnsA2-methoxy-~{n}-[2-methoxy-5-[7-[[(2~{r})-4-(oxetan-3-yl)morpholin-2-yl]methoxy]-1,3-dihydro-2-benzofuran-5-yl]pyridin-3-yl]ethanesulfonamideMouseShow
Pik3cd (p110d)PIKAtypical6zaaA4-[6-methoxy-5-(methylsulfamoyl)pyridin-3-yl]-~{n}-(1-methylpiperidin-4-yl)-2,3-dihydro-1,4-benzoxazine-6-carboxamideMouseShow
Pik3cd (p110d)PIKAtypical6zacAA~{n}-[5-[6-[(dimethylamino)methyl]-2,3-dihydro-1,4-benzoxazin-4-yl]-2-methoxy-pyridin-3-yl]methanesulfonamideMouseShow
Pik3cd (p110d)PIKAtypical6zacAB~{n}-[5-[6-[(dimethylamino)methyl]-2,3-dihydro-1,4-benzoxazin-4-yl]-2-methoxy-pyridin-3-yl]methanesulfonamideMouseShow
Pik3cd (p110d)PIKAtypical6zadAmethoxymethyloxathiatetraazatetracyclodocosahexaenedioneMouseShow
Pik3cd (p110d)PIKAtypical7oi4AAn-[5-[2-[(1s)-1-cyclopropylethyl]-7-[[4-[(dimethylamino)methyl]phenyl]sulfamoyl]-1-oxidanylidene-3h-isoindol-5-yl]-4-methyl-1,3-thiazol-2-yl]ethanamideMouseShow
Pik3cd (p110d)PIKAtypical7oi4ABn-[5-[2-[(1s)-1-cyclopropylethyl]-7-[[4-[(dimethylamino)methyl]phenyl]sulfamoyl]-1-oxidanylidene-3h-isoindol-5-yl]-4-methyl-1,3-thiazol-2-yl]ethanamideMouseShow
Pik3cd (p110d)PIKAtypical7oijAA6-[[5-[2-[(1s)-1-cyclopropylethyl]-7-(methylsulfamoyl)-1-oxidanylidene-3h-isoindol-5-yl]-4-methyl-1,3-thiazol-2-yl]amino]-n-[3-(dimethylamino)propyl]pyridine-2-carboxamideMouseShow
Pik3cd (p110d)PIKAtypical7oijAB6-[[5-[2-[(1s)-1-cyclopropylethyl]-7-(methylsulfamoyl)-1-oxidanylidene-3h-isoindol-5-yl]-4-methyl-1,3-thiazol-2-yl]amino]-n-[3-(dimethylamino)propyl]pyridine-2-carboxamideMouseShow
Pik3cd (p110d)PIKAtypical7oilAA2-[(1s)-1-cyclopropylethyl]-5-[4-methyl-2-[[6-(2-oxidanylidenepyrrolidin-1-yl)pyridin-2-yl]amino]-1,3-thiazol-5-yl]-7-methylsulfonyl-3h-isoindol-1-oneMouseShow
Pik3cd (p110d)PIKAtypical7oilAB2-[(1s)-1-cyclopropylethyl]-5-[4-methyl-2-[[6-(2-oxidanylidenepyrrolidin-1-yl)pyridin-2-yl]amino]-1,3-thiazol-5-yl]-7-methylsulfonyl-3h-isoindol-1-oneMouseShow
Pik3cd (p110d)PIKAtypical7oisAAn-[5-[2-[(1s)-1-cyclopropylethyl]-7-[(3-methylsulfonylphenyl)sulfamoyl]-1-oxidanylidene-3h-isoindol-5-yl]-4-methyl-1,3-thiazol-2-yl]ethanamideMouseShow
Pik3cd (p110d)PIKAtypical7oisABn-[5-[2-[(1s)-1-cyclopropylethyl]-7-[(3-methylsulfonylphenyl)sulfamoyl]-1-oxidanylidene-3h-isoindol-5-yl]-4-methyl-1,3-thiazol-2-yl]ethanamideMouseShow
Pik3cd (p110d)PIKAtypical7popA5-[3,6-dihydro-2h-pyran-4-yl]-2-methoxy-n-[2-methylpyridin-4-yl]pyridine-3-sulfonamideMouseShow
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