PDB-code
Browse kinase entries (page 263 of 282)
First 259 260 261 PreviousLast267 266 265 Next| # | Kinase | Family | Group | PDB | Chain | (Alternate) Model | Orthosteric ligand | Organism | Details | File |
|---|---|---|---|---|---|---|---|---|---|---|
 | SYK | Syk | TK | 4yjs | A | 3-[{2-[(1,1-dioxido-2,3-dihydro-1,2-benzothiazol-6-yl)amino]pyrimidin-4-yl}(1h-indazol-4-yl)amino]propan-1-ol | Human | Show |  | |
| SYK | Syk | TK | 4yjt | A | A | n~2~-(1,1-dioxido-2,3-dihydro-1,2-benzothiazol-6-yl)-n~4~-ethyl-5-fluoro-n~4~-(1h-indazol-4-yl)pyrimidine-2,4-diamine | Human | Show | |
| SYK | Syk | TK | 4yjt | A | B | n~2~-(1,1-dioxido-2,3-dihydro-1,2-benzothiazol-6-yl)-n~4~-ethyl-5-fluoro-n~4~-(1h-indazol-4-yl)pyrimidine-2,4-diamine | Human | Show | |
| SYK | Syk | TK | 4yjt | A | C | n~2~-(1,1-dioxido-2,3-dihydro-1,2-benzothiazol-6-yl)-n~4~-ethyl-5-fluoro-n~4~-(1h-indazol-4-yl)pyrimidine-2,4-diamine | Human | Show | |
| SYK | Syk | TK | 4yju | A | A | n~2~-(1,1-dioxido-2,3-dihydro-1,2-benzothiazol-6-yl)-5-fluoro-n~4~-(1h-indazol-4-yl)-n~4~-methylpyrimidine-2,4-diamine | Human | Show | |
| SYK | Syk | TK | 4yju | A | B | n~2~-(1,1-dioxido-2,3-dihydro-1,2-benzothiazol-6-yl)-5-fluoro-n~4~-(1h-indazol-4-yl)-n~4~-methylpyrimidine-2,4-diamine | Human | Show | |
| SYK | Syk | TK | 4yjv | A | A | 3-[6-({4-[ethyl(1h-indazol-4-yl)amino]-5-fluoropyrimidin-2-yl}amino)-2,4-dihydro-1h-indazol-1-yl]propan-1-ol | Human | Show | |
| SYK | Syk | TK | 4yjv | A | B | 3-[6-({4-[ethyl(1h-indazol-4-yl)amino]-5-fluoropyrimidin-2-yl}amino)-2,4-dihydro-1h-indazol-1-yl]propan-1-ol | Human | Show | |
| SYK | Syk | TK | 4yjv | A | C | 3-[6-({4-[ethyl(1h-indazol-4-yl)amino]-5-fluoropyrimidin-2-yl}amino)-2,4-dihydro-1h-indazol-1-yl]propan-1-ol | Human | Show | |
| SYK | Syk | TK | 5c26 | A | 3-{8-[(3,4-dimethoxyphenyl)amino]imidazo[1,2-a]pyrazin-6-yl}benzamide | Human | Show | | |
| SYK | Syk | TK | 5c27 | A | 3-{8-[(3,4-dimethoxyphenyl)amino]imidazo[1,2-a]pyrazin-6-yl}-n-[4-(methylcarbamoyl)phenyl]benzamide | Human | Show | | |
| SYK | Syk | TK | 5cxh | A | (4r)-4-[(1r)-1-{[6-(3,4-dimethoxyphenyl)[1,3]thiazolo[5,4-c]pyridin-4-yl]oxy}ethyl]pyrrolidin-2-one | Human | Show | | |
| SYK | Syk | TK | 5cxz | A | A | n-{7-[4-(dimethylamino)phenyl]-1,6-naphthyridin-5-yl}propane-1,3-diamine | Human | Show | |
| SYK | Syk | TK | 5cxz | A | B | n-{7-[4-(dimethylamino)phenyl]-1,6-naphthyridin-5-yl}propane-1,3-diamine | Human | Show | |
| SYK | Syk | TK | 5cy3 | A | A | (5r)-5-[(1r)-1-{[6-(1-methyl-1h-pyrazol-4-yl)-2,1-benzothiazol-4-yl]oxy}ethyl]-1,3-oxazolidin-2-one | Human | Show | |
| SYK | Syk | TK | 5cy3 | A | B | (5r)-5-[(1r)-1-{[6-(1-methyl-1h-pyrazol-4-yl)-2,1-benzothiazol-4-yl]oxy}ethyl]-1,3-oxazolidin-2-one | Human | Show | |
| SYK | Syk | TK | 5ghv | A | 1-({1-[2-({3,5-dimethyl-4-[2-(pyrrolidin-1-yl)ethoxy]phenyl}amino)pyrimidin-4-yl]-4-methyl-1h-pyrrol-3-yl}methyl)azetidin-3-ol | Human | Show | | |
| SYK | Syk | TK | 5ghv | B | 1-({1-[2-({3,5-dimethyl-4-[2-(pyrrolidin-1-yl)ethoxy]phenyl}amino)pyrimidin-4-yl]-4-methyl-1h-pyrrol-3-yl}methyl)azetidin-3-ol | Human | Show | | |
| SYK | Syk | TK | 5lma | A | A | ~{n}'-[7-(4-methylphenyl)pyrido[3,4-b]pyrazin-5-yl]butane-1,4-diamine | Human | Show | |
| SYK | Syk | TK | 5lma | A | B | ~{n}'-[7-(4-methylphenyl)pyrido[3,4-b]pyrazin-5-yl]butane-1,4-diamine | Human | Show | |
| SYK | Syk | TK | 5lma | A | C | ~{n}'-[7-(4-methylphenyl)pyrido[3,4-b]pyrazin-5-yl]butane-1,4-diamine | Human | Show | |
| SYK | Syk | TK | 5lmb | A | A | 7-[6-(dimethylamino)pyridin-3-yl]-~{n}-[[(3~{s})-piperidin-3-yl]methyl]pyrido[3,4-b]pyrazin-5-amine | Human | Show | |
| SYK | Syk | TK | 5lmb | A | B | 7-[6-(dimethylamino)pyridin-3-yl]-~{n}-[[(3~{s})-piperidin-3-yl]methyl]pyrido[3,4-b]pyrazin-5-amine | Human | Show | |
| SYK | Syk | TK | 5lmb | B | A | 7-[6-(dimethylamino)pyridin-3-yl]-~{n}-[[(3~{s})-piperidin-3-yl]methyl]pyrido[3,4-b]pyrazin-5-amine | Human | Show | |
| SYK | Syk | TK | 5lmb | B | B | 7-[6-(dimethylamino)pyridin-3-yl]-~{n}-[[(3~{s})-piperidin-3-yl]methyl]pyrido[3,4-b]pyrazin-5-amine | Human | Show | |
| SYK | Syk | TK | 5t68 | A | n~4~-cyclopropyl-n~2~-(3-methyl-1h-indazol-6-yl)furo[3,2-d]pyrimidine-2,4-diamine | Human | Show | | |
| SYK | Syk | TK | 5t68 | B | n~4~-cyclopropyl-n~2~-(3-methyl-1h-indazol-6-yl)furo[3,2-d]pyrimidine-2,4-diamine | Human | Show | | |
| SYK | Syk | TK | 5tiu | A | A | 5-{[(2s)-2-aminopropyl]amino}-3-(1h-indol-2-yl)pyrazine-2-carboxamide | Human | Show | |
| SYK | Syk | TK | 5tiu | A | B | 5-{[(2s)-2-aminopropyl]amino}-3-(1h-indol-2-yl)pyrazine-2-carboxamide | Human | Show | |
| SYK | Syk | TK | 5tr6 | A | A | 6-{[(1r,2s)-2-aminocyclohexyl]amino}-7-fluoro-4-(1-methyl-1h-pyrazol-4-yl)-1,2-dihydro-3h-pyrrolo[3,4-c]pyridin-3-one | Human | Show | |
| SYK | Syk | TK | 5tr6 | A | B | 6-{[(1r,2s)-2-aminocyclohexyl]amino}-7-fluoro-4-(1-methyl-1h-pyrazol-4-yl)-1,2-dihydro-3h-pyrrolo[3,4-c]pyridin-3-one | Human | Show | |
| SYK | Syk | TK | 5tt7 | A | A | 2-{[(1r,2s)-2-aminocyclohexyl]amino}-4-[(3-methylphenyl)amino]-6,7-dihydro-5h-pyrrolo[3,4-d]pyrimidin-5-one | Human | Show | |
| SYK | Syk | TK | 5tt7 | A | B | 2-{[(1r,2s)-2-aminocyclohexyl]amino}-4-[(3-methylphenyl)amino]-6,7-dihydro-5h-pyrrolo[3,4-d]pyrimidin-5-one | Human | Show | |
| SYK | Syk | TK | 5y5t | A | 2-[[(1s,2s)-2-azanylcyclohexyl]amino]-4-[(4-methylsulfonylphenyl)amino]-6h-pyrido[4,3-d]pyrimidin-5-one | Human | Show | | |
| SYK | Syk | TK | 5y5u | A | 4-[(1-methylindazol-5-yl)amino]-2-(4-oxidanylpiperidin-1-yl)-8h-pyrido[4,3-d]pyrimidin-5-one | Human | Show | | |
| SYK | Syk | TK | 5y5u | B | 4-[(1-methylindazol-5-yl)amino]-2-(4-oxidanylpiperidin-1-yl)-8h-pyrido[4,3-d]pyrimidin-5-one | Human | Show | | |
| SYK | Syk | TK | 6hm6 | A | A | 2-(4-methylphenyl)-3-(pyridin-2-ylmethoxy)pyridine | Human | Show | |
| SYK | Syk | TK | 6hm6 | A | B | 2-(4-methylphenyl)-3-(pyridin-2-ylmethoxy)pyridine | Human | Show | |
| SYK | Syk | TK | 6hm7 | A | A | 7-[2-methoxy-6-[(4-methylpyridin-2-yl)methoxy]phenyl]-2,3,4,5-tetrahydro-1~{h}-3-benzazepine | Human | Show | |
| SYK | Syk | TK | 6hm7 | A | B | 7-[2-methoxy-6-[(4-methylpyridin-2-yl)methoxy]phenyl]-2,3,4,5-tetrahydro-1~{h}-3-benzazepine | Human | Show | |
| SYK | Syk | TK | 6ssb | A | ~{n}-[4-[5-[(dimethylamino)methyl]-1-methyl-pyrazol-3-yl]pyrimidin-2-yl]-3-methyl-1-(5-methyl-1,3,4-oxadiazol-2-yl)imidazo[1,5-a]pyridin-7-amine | Human | Show | | |
| SYK | Syk | TK | 6vov | A | 6-(6-aminopyrazin-2-yl)-n-{4-[4-(oxetan-3-yl)piperazin-1-yl]phenyl}imidazo[1,2-a]pyrazin-8-amine | Human | Show | | |
| SYK | Syk | TK | 6vov | B | 6-(6-aminopyrazin-2-yl)-n-{4-[4-(oxetan-3-yl)piperazin-1-yl]phenyl}imidazo[1,2-a]pyrazin-8-amine | Human | Show | | |
| SYK | Syk | TK | 6zc0 | A | ~{n},~{n}-dimethyl-1-[1-[2-(1-methylindol-4-yl)-3~{h}-imidazo[4,5-b]pyridin-7-yl]pyrazol-4-yl]methanamine | Human | Show | | |
| SYK | Syk | TK | 6zcp | A | 7-[[4-[4-[(dimethylamino)methyl]pyrazol-1-yl]pyrimidin-2-yl]amino]-~{n},3-dimethyl-imidazo[1,5-a]pyridine-1-carboxamide | Human | Show | | |
| SYK | Syk | TK | 6zcq | A | 7-[[4-[4-[[(3~{r},4~{r})-3-azanyloxan-4-yl]amino]pyrazol-1-yl]pyrimidin-2-yl]amino]-~{n},3-dimethyl-imidazo[1,5-a]pyridine-1-carboxamide | Human | Show | | |
| SYK | Syk | TK | 6zcr | A | A | 6-chloro-2-(2-fluoro-4,5-dimethoxyphenyl)-n-(piperidin-4-ylmethyl)-3h-imidazo[4,5-b]pyridin-7-amine | Human | Show | |
| SYK | Syk | TK | 6zcr | A | B | 6-chloro-2-(2-fluoro-4,5-dimethoxyphenyl)-n-(piperidin-4-ylmethyl)-3h-imidazo[4,5-b]pyridin-7-amine | Human | Show | |
| SYK | Syk | TK | 6zcs | A | A | (3~{r},4~{r})-~{n}4-[1-[2-(1-methylindol-4-yl)-3~{h}-imidazo[4,5-b]pyridin-7-yl]pyrazol-4-yl]oxane-3,4-diamine | Human | Show | |
| SYK | Syk | TK | 6zcs | A | B | (3~{r},4~{r})-~{n}4-[1-[2-(1-methylindol-4-yl)-3~{h}-imidazo[4,5-b]pyridin-7-yl]pyrazol-4-yl]oxane-3,4-diamine | Human | Show | |
