PDB-code
Browse kinase entries (page 30 of 282)
First 26 27 28 PreviousLast34 33 32 Next| # | Kinase | Family | Group | PDB | Chain | (Alternate) Model | Orthosteric ligand | Organism | Details | File |
|---|---|---|---|---|---|---|---|---|---|---|
 | BTK | Tec | TK | 6w07 | A | B | ~{n}-[[2-methyl-4-[2-[(1-methylpyrazol-4-yl)amino]pyrimidin-4-yl]phenyl]methyl]-3-propan-2-yloxy-azetidine-1-carboxamide | Human | Show |  |
| BTK | Tec | TK | 6w07 | A | C | ~{n}-[[2-methyl-4-[2-[(1-methylpyrazol-4-yl)amino]pyrimidin-4-yl]phenyl]methyl]-3-propan-2-yloxy-azetidine-1-carboxamide | Human | Show | |
| BTK | Tec | TK | 6w7o | A | [5-({[(3s)-2-(n-methyl-l-alanyl-3-methyl-l-valyl)-3-{[(1r)-1,2,3,4-tetrahydronaphthalen-1-yl]carbamoyl}-1,2,3,4-tetrahydroisoquinolin-7-yl]oxy}methyl)pyrazin-2-yl]methyl (3r)-3-{5-amino-4-carbamoyl-3-[4-(2,4-difluorophenoxy)phenyl]-1h-pyrazol-1-yl}piperidine-1-carboxylate | Human | Show | | |
| BTK | Tec | TK | 6w7o | B | [5-({[(3s)-2-(n-methyl-l-alanyl-3-methyl-l-valyl)-3-{[(1r)-1,2,3,4-tetrahydronaphthalen-1-yl]carbamoyl}-1,2,3,4-tetrahydroisoquinolin-7-yl]oxy}methyl)pyrazin-2-yl]methyl (3r)-3-{5-amino-4-carbamoyl-3-[4-(2,4-difluorophenoxy)phenyl]-1h-pyrazol-1-yl}piperidine-1-carboxylate | Human | Show | | |
| BTK | Tec | TK | 6w8i | A | - | Human | Show | | |
| BTK | Tec | TK | 6w8i | B | - | Human | Show | | |
| BTK | Tec | TK | 6x3n | A | A | 4-{8-amino-3-[(6r,8as)-3-oxohexahydro-3h-[1,3]oxazolo[3,4-a]pyridin-6-yl]imidazo[1,5-a]pyrazin-1-yl}-n-[4-(trifluoromethyl)pyridin-2-yl]benzamide | Human | Show | |
| BTK | Tec | TK | 6x3n | A | B | 4-{8-amino-3-[(6r,8as)-3-oxohexahydro-3h-[1,3]oxazolo[3,4-a]pyridin-6-yl]imidazo[1,5-a]pyrazin-1-yl}-n-[4-(trifluoromethyl)pyridin-2-yl]benzamide | Human | Show | |
| BTK | Tec | TK | 6x3o | A | A | 4-{8-amino-3-[(6r,8as)-3-oxo-3,5,6,7,8,8a-hexahydroindolizin-6-yl]imidazo[1,5-a]pyrazin-1-yl}-3-methoxy-n-[4-(trifluoromethyl)pyridin-2-yl]benzamide | Human | Show | |
| BTK | Tec | TK | 6x3o | A | B | 4-{8-amino-3-[(6r,8as)-3-oxo-3,5,6,7,8,8a-hexahydroindolizin-6-yl]imidazo[1,5-a]pyrazin-1-yl}-3-methoxy-n-[4-(trifluoromethyl)pyridin-2-yl]benzamide | Human | Show | |
| BTK | Tec | TK | 6x3o | B | A | 4-{8-amino-3-[(6r,8as)-3-oxo-3,5,6,7,8,8a-hexahydroindolizin-6-yl]imidazo[1,5-a]pyrazin-1-yl}-3-methoxy-n-[4-(trifluoromethyl)pyridin-2-yl]benzamide | Human | Show | |
| BTK | Tec | TK | 6x3o | B | B | 4-{8-amino-3-[(6r,8as)-3-oxo-3,5,6,7,8,8a-hexahydroindolizin-6-yl]imidazo[1,5-a]pyrazin-1-yl}-3-methoxy-n-[4-(trifluoromethyl)pyridin-2-yl]benzamide | Human | Show | |
| BTK | Tec | TK | 6x3p | A | A | 4-{8-amino-3-[(6r,8as)-3-oxooctahydroindolizin-6-yl]imidazo[1,5-a]pyrazin-1-yl}-3-(cyclopropyloxy)-n-[4-(trifluoromethyl)pyridin-2-yl]benzamide | Human | Show | |
| BTK | Tec | TK | 6x3p | A | B | 4-{8-amino-3-[(6r,8as)-3-oxooctahydroindolizin-6-yl]imidazo[1,5-a]pyrazin-1-yl}-3-(cyclopropyloxy)-n-[4-(trifluoromethyl)pyridin-2-yl]benzamide | Human | Show | |
| BTK | Tec | TK | 6xe4 | A | A | (1s,2s)-n-[2'-(6-tert-butyl-8-fluoro-1-oxophthalazin-2(1h)-yl)-3'-(hydroxymethyl)-1-methyl-6-oxo[1,6-dihydro[3,4'-bipyridine]]-5-yl]-2-fluorocyclopropane-1-carboxamide | Human | Show | |
| BTK | Tec | TK | 6xe4 | A | B | (1s,2s)-n-[2'-(6-tert-butyl-8-fluoro-1-oxophthalazin-2(1h)-yl)-3'-(hydroxymethyl)-1-methyl-6-oxo[1,6-dihydro[3,4'-bipyridine]]-5-yl]-2-fluorocyclopropane-1-carboxamide | Human | Show | |
| BTK | Tec | TK | 7kxl | A | A | 3-tert-butyl-n-({2-fluoro-4-[2-(1-methyl-1h-pyrazol-4-yl)-1h-imidazo[4,5-b]pyridin-7-yl]phenyl}methyl)-1,2,4-oxadiazole-5-carboxamide | Human | Show | |
| BTK | Tec | TK | 7kxl | A | B | 3-tert-butyl-n-({2-fluoro-4-[2-(1-methyl-1h-pyrazol-4-yl)-1h-imidazo[4,5-b]pyridin-7-yl]phenyl}methyl)-1,2,4-oxadiazole-5-carboxamide | Human | Show | |
| BTK | Tec | TK | 7kxl | A | C | 3-tert-butyl-n-({2-fluoro-4-[2-(1-methyl-1h-pyrazol-4-yl)-1h-imidazo[4,5-b]pyridin-7-yl]phenyl}methyl)-1,2,4-oxadiazole-5-carboxamide | Human | Show | |
| BTK | Tec | TK | 7kxm | A | A | 4-tert-butyl-n-(2-methyl-3-{2-[4-(morpholine-4-carbonyl)phenyl]-1h-imidazo[4,5-b]pyridin-7-yl}phenyl)benzamide | Human | Show | |
| BTK | Tec | TK | 7kxm | A | B | 4-tert-butyl-n-(2-methyl-3-{2-[4-(morpholine-4-carbonyl)phenyl]-1h-imidazo[4,5-b]pyridin-7-yl}phenyl)benzamide | Human | Show | |
| BTK | Tec | TK | 7kxm | A | C | 4-tert-butyl-n-(2-methyl-3-{2-[4-(morpholine-4-carbonyl)phenyl]-1h-imidazo[4,5-b]pyridin-7-yl}phenyl)benzamide | Human | Show | |
| BTK | Tec | TK | 7kxn | A | A | 3-tert-butyl-n-[(1s)-6-{2-[5-methyl-1-(propan-2-yl)-1h-pyrazol-4-yl]-1h-imidazo[4,5-b]pyridin-7-yl}-1,2,3,4-tetrahydronaphthalen-1-yl]-1,2,4-oxadiazole-5-carboxamide | Human | Show | |
| BTK | Tec | TK | 7kxn | A | B | 3-tert-butyl-n-[(1s)-6-{2-[5-methyl-1-(propan-2-yl)-1h-pyrazol-4-yl]-1h-imidazo[4,5-b]pyridin-7-yl}-1,2,3,4-tetrahydronaphthalen-1-yl]-1,2,4-oxadiazole-5-carboxamide | Human | Show | |
| BTK | Tec | TK | 7kxn | A | C | 3-tert-butyl-n-[(1s)-6-{2-[5-methyl-1-(propan-2-yl)-1h-pyrazol-4-yl]-1h-imidazo[4,5-b]pyridin-7-yl}-1,2,3,4-tetrahydronaphthalen-1-yl]-1,2,4-oxadiazole-5-carboxamide | Human | Show | |
| BTK | Tec | TK | 7kxo | A | A | 3-tert-butyl-n-[(1r)-6-{2-[5-methyl-1-(oxan-4-yl)-1h-pyrazol-4-yl]-3h-imidazo[4,5-b]pyridin-7-yl}-1,2,3,4-tetrahydronaphthalen-1-yl]-1,2,4-oxadiazole-5-carboxamide | Human | Show | |
| BTK | Tec | TK | 7kxo | A | B | 3-tert-butyl-n-[(1r)-6-{2-[5-methyl-1-(oxan-4-yl)-1h-pyrazol-4-yl]-3h-imidazo[4,5-b]pyridin-7-yl}-1,2,3,4-tetrahydronaphthalen-1-yl]-1,2,4-oxadiazole-5-carboxamide | Human | Show | |
| BTK | Tec | TK | 7kxo | A | C | 3-tert-butyl-n-[(1r)-6-{2-[5-methyl-1-(oxan-4-yl)-1h-pyrazol-4-yl]-3h-imidazo[4,5-b]pyridin-7-yl}-1,2,3,4-tetrahydronaphthalen-1-yl]-1,2,4-oxadiazole-5-carboxamide | Human | Show | |
| BTK | Tec | TK | 7kxp | A | A | 3-tert-butyl-n-[(1s)-6-{2-[3-methyl-1-(oxan-4-yl)-1h-pyrazol-4-yl]-1h-imidazo[4,5-b]pyridin-7-yl}-1,2,3,4-tetrahydronaphthalen-1-yl]-1,2,4-oxadiazole-5-carboxamide | Human | Show | |
| BTK | Tec | TK | 7kxp | A | B | 3-tert-butyl-n-[(1s)-6-{2-[3-methyl-1-(oxan-4-yl)-1h-pyrazol-4-yl]-1h-imidazo[4,5-b]pyridin-7-yl}-1,2,3,4-tetrahydronaphthalen-1-yl]-1,2,4-oxadiazole-5-carboxamide | Human | Show | |
| BTK | Tec | TK | 7kxq | A | A | 3-tert-butyl-n-[(5r)-2-{2-[3,5-dimethyl-1-(propan-2-yl)-1h-pyrazol-4-yl]-3h-imidazo[4,5-b]pyridin-7-yl}-6,7,8,9-tetrahydro-5h-benzo[7]annulen-5-yl]-1,2,4-oxadiazole-5-carboxamide | Human | Show | |
| BTK | Tec | TK | 7kxq | A | B | 3-tert-butyl-n-[(5r)-2-{2-[3,5-dimethyl-1-(propan-2-yl)-1h-pyrazol-4-yl]-3h-imidazo[4,5-b]pyridin-7-yl}-6,7,8,9-tetrahydro-5h-benzo[7]annulen-5-yl]-1,2,4-oxadiazole-5-carboxamide | Human | Show | |
| BTK | Tec | TK | 7l5o | A | A | (2e)-2-{(3r)-3-[4-amino-3-(2-fluoro-4-phenoxyphenyl)-1h-pyrazolo[3,4-d]pyrimidin-1-yl]piperidine-1-carbonyl}-4-methyl-4-[4-(oxetan-3-yl)piperazin-1-yl]pent-2-enenitrile | Human | Show | |
| BTK | Tec | TK | 7l5o | A | B | (2e)-2-{(3r)-3-[4-amino-3-(2-fluoro-4-phenoxyphenyl)-1h-pyrazolo[3,4-d]pyrimidin-1-yl]piperidine-1-carbonyl}-4-methyl-4-[4-(oxetan-3-yl)piperazin-1-yl]pent-2-enenitrile | Human | Show | |
| BTK | Tec | TK | 7l5o | A | C | (2e)-2-{(3r)-3-[4-amino-3-(2-fluoro-4-phenoxyphenyl)-1h-pyrazolo[3,4-d]pyrimidin-1-yl]piperidine-1-carbonyl}-4-methyl-4-[4-(oxetan-3-yl)piperazin-1-yl]pent-2-enenitrile | Human | Show | |
| BTK | Tec | TK | 7l5p | A | A | (2e)-2-{(3r)-3-[4-amino-3-(2-fluoro-4-phenoxyphenyl)-1h-pyrazolo[3,4-d]pyrimidin-1-yl]piperidine-1-carbonyl}-4-methyl-4-[4-(oxetan-3-yl)piperazin-1-yl]pent-2-enenitrile | Human | Show | |
| BTK | Tec | TK | 7l5p | A | B | (2e)-2-{(3r)-3-[4-amino-3-(2-fluoro-4-phenoxyphenyl)-1h-pyrazolo[3,4-d]pyrimidin-1-yl]piperidine-1-carbonyl}-4-methyl-4-[4-(oxetan-3-yl)piperazin-1-yl]pent-2-enenitrile | Human | Show | |
| BTK | Tec | TK | 7lty | A | A | ~{n}-[(5~{r})-2-[2-[(1-methylpyrazol-4-yl)amino]pyrimidin-4-yl]-6,7,8,9-tetrahydro-5~{h}-benzo[7]annulen-5-yl]-3-propan-2-yloxy-azetidine-1-carboxamide | Human | Show | |
| BTK | Tec | TK | 7lty | A | B | ~{n}-[(5~{r})-2-[2-[(1-methylpyrazol-4-yl)amino]pyrimidin-4-yl]-6,7,8,9-tetrahydro-5~{h}-benzo[7]annulen-5-yl]-3-propan-2-yloxy-azetidine-1-carboxamide | Human | Show | |
| BTK | Tec | TK | 7lty | A | C | ~{n}-[(5~{r})-2-[2-[(1-methylpyrazol-4-yl)amino]pyrimidin-4-yl]-6,7,8,9-tetrahydro-5~{h}-benzo[7]annulen-5-yl]-3-propan-2-yloxy-azetidine-1-carboxamide | Human | Show | |
| BTK | Tec | TK | 7lty | A | D | ~{n}-[(5~{r})-2-[2-[(1-methylpyrazol-4-yl)amino]pyrimidin-4-yl]-6,7,8,9-tetrahydro-5~{h}-benzo[7]annulen-5-yl]-3-propan-2-yloxy-azetidine-1-carboxamide | Human | Show | |
| BTK | Tec | TK | 7ltz | A | A | 1-~{tert}-butyl-~{n}-[(5~{r})-8-[2-[(1-methylpyrazol-4-yl)amino]pyrimidin-4-yl]-2-(oxetan-3-yl)-1,3,4,5-tetrahydro-2-benzazepin-5-yl]-1,2,3-triazole-4-carboxamide | Human | Show | |
| BTK | Tec | TK | 7ltz | A | B | 1-~{tert}-butyl-~{n}-[(5~{r})-8-[2-[(1-methylpyrazol-4-yl)amino]pyrimidin-4-yl]-2-(oxetan-3-yl)-1,3,4,5-tetrahydro-2-benzazepin-5-yl]-1,2,3-triazole-4-carboxamide | Human | Show | |
| BTK | Tec | TK | 7n4q | A | A | (2r)-2-(3-chloro-5-fluoroanilino)-2-cyclopropyl-n-[(3r)-1-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)piperidin-3-yl]acetamide | Human | Show | |
| BTK | Tec | TK | 7n4q | A | B | (2r)-2-(3-chloro-5-fluoroanilino)-2-cyclopropyl-n-[(3r)-1-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)piperidin-3-yl]acetamide | Human | Show | |
| BTK | Tec | TK | 7n4r | A | A | n-{2-[methyl(7h-pyrrolo[2,3-d]pyrimidin-4-yl)amino]ethyl}-n~2~-phenylglycinamide | Human | Show | |
| BTK | Tec | TK | 7n4r | A | B | n-{2-[methyl(7h-pyrrolo[2,3-d]pyrimidin-4-yl)amino]ethyl}-n~2~-phenylglycinamide | Human | Show | |
| BTK | Tec | TK | 7n4r | A | C | n-{2-[methyl(7h-pyrrolo[2,3-d]pyrimidin-4-yl)amino]ethyl}-n~2~-phenylglycinamide | Human | Show | |
| BTK | Tec | TK | 7n4s | A | (3r,3'r)-3-anilino-1'-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)[1,3'-bipiperidin]-2-one | Human | Show | | |
| BTK | Tec | TK | 7n5o | A | A | 5-(1h-benzimidazol-2-yl)-2,4-dihydro-3h-1,2,4-triazol-3-one | Human | Show | |
