PDB-code
Browse kinase entries (page 31 of 282)
First 27 28 29 PreviousLast35 34 33 Next| # | Kinase | Family | Group | PDB | Chain | (Alternate) Model | Orthosteric ligand | Organism | Details | File |
|---|---|---|---|---|---|---|---|---|---|---|
 | BTK | Tec | TK | 7n5o | A | B | 5-(1h-benzimidazol-2-yl)-2,4-dihydro-3h-1,2,4-triazol-3-one | Human | Show |  |
| BTK | Tec | TK | 7n5r | A | A | 5-phenyl-2,4-dihydro-3h-1,2,4-triazol-3-one | Human | Show | |
| BTK | Tec | TK | 7n5r | A | B | 5-phenyl-2,4-dihydro-3h-1,2,4-triazol-3-one | Human | Show | |
| BTK | Tec | TK | 7n5x | A | A | 5-(1-ethoxyisoquinolin-3-yl)-2,4-dihydro-3h-1,2,4-triazol-3-one | Human | Show | |
| BTK | Tec | TK | 7n5x | A | B | 5-(1-ethoxyisoquinolin-3-yl)-2,4-dihydro-3h-1,2,4-triazol-3-one | Human | Show | |
| BTK | Tec | TK | 7n5y | A | A | 5-(1-{[(3s)-1-propanoylpyrrolidin-3-yl]oxy}isoquinolin-3-yl)-2,4-dihydro-3h-1,2,4-triazol-3-one | Human | Show | |
| BTK | Tec | TK | 7n5y | A | B | 5-(1-{[(3s)-1-propanoylpyrrolidin-3-yl]oxy}isoquinolin-3-yl)-2,4-dihydro-3h-1,2,4-triazol-3-one | Human | Show | |
| BTK | Tec | TK | 7r60 | A | A | 2-(4-phenoxyphenoxy)-5-[(3r)-1-(prop-2-enoyl)piperidin-3-yl]pyridine-3-carboxamide | Human | Show | |
| BTK | Tec | TK | 7r60 | A | B | 2-(4-phenoxyphenoxy)-5-[(3r)-1-(prop-2-enoyl)piperidin-3-yl]pyridine-3-carboxamide | Human | Show | |
| BTK | Tec | TK | 7r61 | A | A | 5-{(3s)-1-[(z)-iminomethyl]piperidin-3-yl}-2-(4-phenoxyphenoxy)pyridine-3-carboxamide | Human | Show | |
| BTK | Tec | TK | 7r61 | A | B | 5-{(3s)-1-[(z)-iminomethyl]piperidin-3-yl}-2-(4-phenoxyphenoxy)pyridine-3-carboxamide | Human | Show | |
| BTK | Tec | TK | 7r61 | A | C | 5-{(3s)-1-[(z)-iminomethyl]piperidin-3-yl}-2-(4-phenoxyphenoxy)pyridine-3-carboxamide | Human | Show | |
| BTK | Tec | TK | 7yc9 | A | A | (7~{s})-2-(4-bromanyl-3,5-dimethoxy-phenyl)-7-(1-propanoylpiperidin-4-yl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide | Human | Show | |
| BTK | Tec | TK | 7yc9 | A | B | (7~{s})-2-(4-bromanyl-3,5-dimethoxy-phenyl)-7-(1-propanoylpiperidin-4-yl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide | Human | Show | |
| BTK | Tec | TK | 8e2m | A | A | (5p)-5-[4-methyl-6-(2-methylpropyl)pyridin-3-yl]-4-oxo-n-[(1r,2s)-2-propanamidocyclopentyl]-4,5-dihydro-3h-1-thia-3,5,8-triazaacenaphthylene-2-carboxamide | Human | Show | |
| BTK | Tec | TK | 8e2m | A | B | (5p)-5-[4-methyl-6-(2-methylpropyl)pyridin-3-yl]-4-oxo-n-[(1r,2s)-2-propanamidocyclopentyl]-4,5-dihydro-3h-1-thia-3,5,8-triazaacenaphthylene-2-carboxamide | Human | Show | |
| BTK | Tec | TK | 8e2m | A | C | (5p)-5-[4-methyl-6-(2-methylpropyl)pyridin-3-yl]-4-oxo-n-[(1r,2s)-2-propanamidocyclopentyl]-4,5-dihydro-3h-1-thia-3,5,8-triazaacenaphthylene-2-carboxamide | Human | Show | |
| BTK | Tec | TK | 8ejb | A | A | 5-[(3r)-3-(3-methyl-2-oxoimidazolidin-1-yl)piperidin-1-yl]-3-[4-(piperidin-4-yl)anilino]pyrazine-2-carboxamide | Human | Show | |
| BTK | Tec | TK | 8ejb | A | B | 5-[(3r)-3-(3-methyl-2-oxoimidazolidin-1-yl)piperidin-1-yl]-3-[4-(piperidin-4-yl)anilino]pyrazine-2-carboxamide | Human | Show | |
| BTK | Tec | TK | 8flg | A | A | n~2~-(3-chlorophenyl)-n-[(3r)-1-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)piperidin-3-yl]glycinamide | Human | Show | |
| BTK | Tec | TK | 8flg | A | B | n~2~-(3-chlorophenyl)-n-[(3r)-1-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)piperidin-3-yl]glycinamide | Human | Show | |
| BTK | Tec | TK | 8flh | A | A | 2-(3,5-dichloroanilino)-1-{(3r)-3-[methyl(7h-pyrrolo[2,3-d]pyrimidin-4-yl)amino]azepan-1-yl}ethan-1-one | Human | Show | |
| BTK | Tec | TK | 8flh | A | B | 2-(3,5-dichloroanilino)-1-{(3r)-3-[methyl(7h-pyrrolo[2,3-d]pyrimidin-4-yl)amino]azepan-1-yl}ethan-1-one | Human | Show | |
| BTK | Tec | TK | 8flh | A | C | 2-(3,5-dichloroanilino)-1-{(3r)-3-[methyl(7h-pyrrolo[2,3-d]pyrimidin-4-yl)amino]azepan-1-yl}ethan-1-one | Human | Show | |
| BTK | Tec | TK | 8fll | A | A | pirtobrutinib | Human | Show | |
| BTK | Tec | TK | 8fll | A | B | pirtobrutinib | Human | Show | |
| BTK | Tec | TK | 8fln | A | A | pirtobrutinib | Human | Show | |
| BTK | Tec | TK | 8fln | A | B | pirtobrutinib | Human | Show | |
| BTK | Tec | TK | 8fln | A | C | pirtobrutinib | Human | Show | |
| BTK | Tec | TK | 8flv | A | A | 2-(3,5-dichloroanilino)-1-{(3r)-3-[methyl(7h-pyrrolo[2,3-d]pyrimidin-4-yl)amino]piperidin-1-yl}ethan-1-one | Human | Show | |
| BTK | Tec | TK | 8flv | A | B | 2-(3,5-dichloroanilino)-1-{(3r)-3-[methyl(7h-pyrrolo[2,3-d]pyrimidin-4-yl)amino]piperidin-1-yl}ethan-1-one | Human | Show | |
| BTK | Tec | TK | 8flv | A | C | 2-(3,5-dichloroanilino)-1-{(3r)-3-[methyl(7h-pyrrolo[2,3-d]pyrimidin-4-yl)amino]piperidin-1-yl}ethan-1-one | Human | Show | |
| BTK | Tec | TK | 8gc7 | A | A | 5-(piperidin-1-yl)-3-[4-(piperidin-4-yl)anilino]pyrazine-2-carboxamide | Human | Show | |
| BTK | Tec | TK | 8gc7 | A | B | 5-(piperidin-1-yl)-3-[4-(piperidin-4-yl)anilino]pyrazine-2-carboxamide | Human | Show | |
| BTK | Tec | TK | 8gc8 | A | A | 5-(piperidin-1-yl)-3-[4-(piperidin-4-yl)anilino]pyrazine-2-carboxamide | Human | Show | |
| BTK | Tec | TK | 8gc8 | A | B | 5-(piperidin-1-yl)-3-[4-(piperidin-4-yl)anilino]pyrazine-2-carboxamide | Human | Show | |
| BTK | Tec | TK | 8tu3 | A | A | 1-[(4r)-4-{[(6p,8s)-6-(1-methyl-1h-pyrazol-4-yl)pyrazolo[1,5-a]pyrazin-4-yl]oxy}azepan-1-yl]propan-1-one | Human | Show | |
| BTK | Tec | TK | 8tu3 | A | B | 1-[(4r)-4-{[(6p,8s)-6-(1-methyl-1h-pyrazol-4-yl)pyrazolo[1,5-a]pyrazin-4-yl]oxy}azepan-1-yl]propan-1-one | Human | Show | |
| BTK | Tec | TK | 8tu3 | A | C | 1-[(4r)-4-{[(6p,8s)-6-(1-methyl-1h-pyrazol-4-yl)pyrazolo[1,5-a]pyrazin-4-yl]oxy}azepan-1-yl]propan-1-one | Human | Show | |
| BTK | Tec | TK | 8tu4 | A | A | n-methyl-n-[(1s,3r)-3-methyl-3-{[(6m,8s)-6-(1-methyl-1h-pyrazol-4-yl)pyrazolo[1,5-a]pyrazin-4-yl]oxy}cyclobutyl]propanamide | Human | Show | |
| BTK | Tec | TK | 8tu4 | A | B | n-methyl-n-[(1s,3r)-3-methyl-3-{[(6m,8s)-6-(1-methyl-1h-pyrazol-4-yl)pyrazolo[1,5-a]pyrazin-4-yl]oxy}cyclobutyl]propanamide | Human | Show | |
| BTK | Tec | TK | 8tu4 | A | C | n-methyl-n-[(1s,3r)-3-methyl-3-{[(6m,8s)-6-(1-methyl-1h-pyrazol-4-yl)pyrazolo[1,5-a]pyrazin-4-yl]oxy}cyclobutyl]propanamide | Human | Show | |
| BTK | Tec | TK | 8tu5 | A | A | 1-[(1s,5s,6s)-6-methyl-6-{[(6m,8r)-6-(1-methyl-1h-pyrazol-4-yl)pyrazolo[1,5-a]pyrazin-4-yl]oxy}-2-azabicyclo[3.2.0]heptan-2-yl]propan-1-one | Human | Show | |
| BTK | Tec | TK | 8tu5 | A | B | 1-[(1s,5s,6s)-6-methyl-6-{[(6m,8r)-6-(1-methyl-1h-pyrazol-4-yl)pyrazolo[1,5-a]pyrazin-4-yl]oxy}-2-azabicyclo[3.2.0]heptan-2-yl]propan-1-one | Human | Show | |
| BTK | Tec | TK | 8tu5 | A | C | 1-[(1s,5s,6s)-6-methyl-6-{[(6m,8r)-6-(1-methyl-1h-pyrazol-4-yl)pyrazolo[1,5-a]pyrazin-4-yl]oxy}-2-azabicyclo[3.2.0]heptan-2-yl]propan-1-one | Human | Show | |
| BTK | Tec | TK | 8u2d | A | A | (3r)-2-[n-(1h-indazole-5-carbonyl)-3-methyl-d-phenylalanyl]-n-methyl-2,3,4,9-tetrahydro-1h-pyrido[3,4-b]indole-3-carboxamide | Human | Show | |
| BTK | Tec | TK | 8u2d | A | B | (3r)-2-[n-(1h-indazole-5-carbonyl)-3-methyl-d-phenylalanyl]-n-methyl-2,3,4,9-tetrahydro-1h-pyrido[3,4-b]indole-3-carboxamide | Human | Show | |
| BTK | Tec | TK | 8u2e | A | A | (2s)-6-fluoro-5-[(3s)-3-(3-methyl-2-oxoimidazolidin-1-yl)piperidin-1-yl]-2-(4-methylpiperazine-1-carbonyl)-2,3,4,9-tetrahydro-1h-carbazole-8-carboxamide | Human | Show | |
| BTK | Tec | TK | 8u2e | A | B | (2s)-6-fluoro-5-[(3s)-3-(3-methyl-2-oxoimidazolidin-1-yl)piperidin-1-yl]-2-(4-methylpiperazine-1-carbonyl)-2,3,4,9-tetrahydro-1h-carbazole-8-carboxamide | Human | Show | |
| BTK | Tec | TK | 8yvv | A | A | - | Human | Show | |
