PDB-code
Search results (17 entries covering 14 PDB structures)
| # | Kinase | Family | Group | PDB | Chain | (Alternate) Model | Orthosteric ligand | Organism | Details | File |
|---|---|---|---|---|---|---|---|---|---|---|
 | PIK3CD (p110d) | PIK | Atypical | 5m6u | A | 4-azanyl-6-[[(1~{s})-1-(4-oxidanylidene-3-phenyl-pyrrolo[2,1-f][1,2,4]triazin-2-yl)ethyl]amino]pyrimidine-5-carbonitrile | Human | Show |  | |
| PIK3CD (p110d) | PIK | Atypical | 7jis | A | (3s)-3-benzyl-5-[9-ethyl-8-(2-methylpyrimidin-5-yl)-9h-purin-6-yl]-3-methyl-1,3-dihydro-2h-indol-2-one | Human | Show | | |
| PIK3CD (p110d) | PIK | Atypical | 6g6w | A | A | ~{n}-[3-[4-[[(1~{s})-1-(5-methyl-4-oxidanylidene-3-phenyl-pyrrolo[2,1-f][1,2,4]triazin-2-yl)ethyl]amino]-7~{h}-pyrrolo[2,3-d]pyrimidin-5-yl]-5-oxidanyl-phenyl]methanesulfonamide | Human | Show | |
| PIK3CD (p110d) | PIK | Atypical | 7lm2 | A | cyclopropyl[(3s)-3-{[9-ethyl-8-(2-methylpyrimidin-5-yl)-9h-purin-6-yl]amino}pyrrolidin-1-yl]methanone | Human | Show | | |
| PIK3CD (p110d) | PIK | Atypical | 5vlr | A | 4-acetyl-1-(3-{4-amino-5-[1-(2,2,2-trifluoroethyl)-1h-pyrazol-5-yl]pyrrolo[2,1-f][1,2,4]triazin-7-yl}phenyl)-3,3-dimethylpiperazin-2-one | Human | Show | | |
| PIK3CD (p110d) | PIK | Atypical | 5ubt | A | 1-[4-(3-{4-amino-5-[1-(oxan-4-yl)-1h-pyrazol-5-yl]pyrrolo[2,1-f][1,2,4]triazin-7-yl}phenyl)piperazin-1-yl]ethan-1-one | Human | Show | | |
| PIK3CD (p110d) | PIK | Atypical | 6pyr | A | B | (3s)-3-benzyl-3-methyl-5-[5-(2-methylpyrimidin-5-yl)pyrazolo[1,5-a]pyrimidin-3-yl]-1,3-dihydro-2h-indol-2-one | Human | Show | |
| PIK3CD (p110d) | PIK | Atypical | 5dxu | A | (2s)-2-({2-[1-(propan-2-yl)-1h-1,2,4-triazol-5-yl]-5,6-dihydroimidazo[1,2-d][1,4]benzoxazepin-9-yl}oxy)propanamide | Human | Show | | |
| PIK3CD (p110d) | PIK | Atypical | 6ocu | A | 5-{(3r)-3-methyl-4-[(1r,2r)-2-methylcyclopropane-1-carbonyl]piperazin-1-yl}-3-(1-methyl-1h-pyrazol-4-yl)pyrazine-2-carbonitrile | Human | Show | | |
| PIK3CD (p110d) | PIK | Atypical | 6pyr | A | A | (3s)-3-benzyl-3-methyl-5-[5-(2-methylpyrimidin-5-yl)pyrazolo[1,5-a]pyrimidin-3-yl]-1,3-dihydro-2h-indol-2-one | Human | Show | |
| PIK3CD (p110d) | PIK | Atypical | 6g6w | A | B | ~{n}-[3-[4-[[(1~{s})-1-(5-methyl-4-oxidanylidene-3-phenyl-pyrrolo[2,1-f][1,2,4]triazin-2-yl)ethyl]amino]-7~{h}-pyrrolo[2,3-d]pyrimidin-5-yl]-5-oxidanyl-phenyl]methanesulfonamide | Human | Show | |
| PIK3CD (p110d) | PIK | Atypical | 6pyu | A | (3s)-1'-(cyclopropanecarbonyl)-5-(quinoxalin-6-yl)spiro[indole-3,2'-pyrrolidin]-2(1h)-one | Human | Show | | |
| PIK3CD (p110d) | PIK | Atypical | 8bcy | A | A | 9-[2-(3,4-dichlorophenyl)ethyl]-2-(3-hydroxyphenyl)-8-oxidanylidene-7~{h}-purine-6-carboxamide | Human | Show | |
| PIK3CD (p110d) | PIK | Atypical | 8bcy | A | B | 9-[2-(3,4-dichlorophenyl)ethyl]-2-(3-hydroxyphenyl)-8-oxidanylidene-7~{h}-purine-6-carboxamide | Human | Show | |
| PIK3CD (p110d) | PIK | Atypical | 7lq1 | A | n-(5-(6-(2-((2s,6r)-2,6-dimethylmorpholino)pyridin-4-yl)-1-oxoisoindolin-4-yl)-2-methoxypyridin-3-yl)methanesulfonamide | Human | Show | | |
| PIK3CD (p110d) | PIK | Atypical | 5t8f | A | 2-methyl-2-(4-{2-[3-methyl-1-(propan-2-yl)-1h-1,2,4-triazol-5-yl]-5,6-dihydroimidazo[1,2-d][1,4]benzoxazepin-9-yl}-1h-pyrazol-1-yl)propanamide | Human | Show | | |
| PIK3CD (p110d) | PIK | Atypical | 6oco | A | 4-[(1s,4s)-5-(3-chlorophenyl)-2,5-diazabicyclo[2.2.1]heptan-2-yl]-2-(pyridin-3-yl)pyrimidine-5-carbonitrile | Human | Show | |
