Search results (54 entries covering 19 PDB structures)

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#	Kinase	Family	Group	PDB	Chain	(Alternate) Model	Orthosteric ligand	Organism	Details	File
	CLK3	CLK	CMGC	2wu6	A	A	5-amino-3-{[4-(aminosulfonyl)phenyl]amino}-n-(2,6-difluorophenyl)-1h-1,2,4-triazole-1-carbothioamide	Human	Show
	CLK3	CLK	CMGC	6z53	A	B	6-(2-methoxyethoxy)-11,15-dimethyl-8-oxa-2,11,15,19,21,23-hexazatetracyclo[15.6.1.13,7.020,24]pentacosa-1(23),3(25),4,6,17,20(24),21-heptaen-10-one	Human	Show
	CLK3	CLK	CMGC	6yu1	a	A	(4~{s})-7,8-bis(chloranyl)-9-methyl-1-oxidanylidene-spiro[2,4-dihydropyrido[3,4-b]indole-3,4'-piperidine]-4-carbonitrile	Human	Show
	CLK3	CLK	CMGC	6z2v	A	B	(4~{s})-7,8-bis(chloranyl)-9-methyl-1-oxidanylidene-spiro[2,4-dihydropyrido[3,4-b]indole-3,4'-piperidine]-4-carbonitrile	Human	Show
	CLK3	CLK	CMGC	6rct	A	A	4-[2-methyl-1-(4-methylpiperazin-1-yl)-1-oxidanylidene-propan-2-yl]-~{n}-(6-pyridin-4-ylimidazo[1,2-a]pyridin-2-yl)benzamide	Human	Show
	CLK3	CLK	CMGC	6ft7	A	B	3-phenyl-1~{h}-pyrrolo[3,4-g]indol-8-one	Human	Show
	CLK3	CLK	CMGC	6z52	B	B	11,15-dimethyl-6-(4-methylpiperazin-1-yl)-8-oxa-2,11,15,19,21,23-hexazatetracyclo[15.6.1.13,7.020,24]pentacosa-1(23),3(25),4,6,17,20(24),21-heptaen-10-one	Human	Show
	CLK3	CLK	CMGC	6z53	A	A	6-(2-methoxyethoxy)-11,15-dimethyl-8-oxa-2,11,15,19,21,23-hexazatetracyclo[15.6.1.13,7.020,24]pentacosa-1(23),3(25),4,6,17,20(24),21-heptaen-10-one	Human	Show
	CLK3	CLK	CMGC	3raw	B	A	5-(1,3-benzodioxol-5-ylmethyl)-2-(phenylamino)-4h-imidazol-4-one	Human	Show
	CLK3	CLK	CMGC	6yty	A	A	(1~{z})-1-(3-ethyl-5-methoxy-1,3-benzothiazol-2-ylidene)propan-2-one	Human	Show
	CLK3	CLK	CMGC	2wu7	A	A	ethyl 3-[(e)-2-amino-1-cyanoethenyl]-6,7-dichloro-1-methyl-1h-indole-2-carboxylate	Human	Show
	CLK3	CLK	CMGC	2exe	A	A	-	Human	Show
	CLK3	CLK	CMGC	6ytw	A	B	(1~{z})-1-(3-ethyl-5-methoxy-1,3-benzothiazol-2-ylidene)propan-2-one	Human	Show
	CLK3	CLK	CMGC	6z52	B	A	11,15-dimethyl-6-(4-methylpiperazin-1-yl)-8-oxa-2,11,15,19,21,23-hexazatetracyclo[15.6.1.13,7.020,24]pentacosa-1(23),3(25),4,6,17,20(24),21-heptaen-10-one	Human	Show
	CLK3	CLK	CMGC	6z52	A	A	11,15-dimethyl-6-(4-methylpiperazin-1-yl)-8-oxa-2,11,15,19,21,23-hexazatetracyclo[15.6.1.13,7.020,24]pentacosa-1(23),3(25),4,6,17,20(24),21-heptaen-10-one	Human	Show
	CLK3	CLK	CMGC	6z55	A	C	7,10-dioxa-13,17,18,21-tetrazatetracyclo[12.5.2.12,6.017,20]docosa-1(20),2(22),3,5,14(21),15,18-heptaene-5-carboxylic acid	Human	Show
	CLK3	CLK	CMGC	2wu7	A	B	ethyl 3-[(e)-2-amino-1-cyanoethenyl]-6,7-dichloro-1-methyl-1h-indole-2-carboxylate	Human	Show
	CLK3	CLK	CMGC	6khf	A	B	5-[(3-chlorophenyl)amino]benzo[c][2,6]naphthyridine-8-carboxylic acid	Human	Show
	CLK3	CLK	CMGC	2eu9	A	A	-	Human	Show
	CLK3	CLK	CMGC	6rct	B	B	4-[2-methyl-1-(4-methylpiperazin-1-yl)-1-oxidanylidene-propan-2-yl]-~{n}-(6-pyridin-4-ylimidazo[1,2-a]pyridin-2-yl)benzamide	Human	Show
	CLK3	CLK	CMGC	6ytw	A	A	(1~{z})-1-(3-ethyl-5-methoxy-1,3-benzothiazol-2-ylidene)propan-2-one	Human	Show
	CLK3	CLK	CMGC	6z55	B	C	7,10-dioxa-13,17,18,21-tetrazatetracyclo[12.5.2.12,6.017,20]docosa-1(20),2(22),3,5,14(21),15,18-heptaene-5-carboxylic acid	Human	Show
	CLK3	CLK	CMGC	6ft7	A	A	3-phenyl-1~{h}-pyrrolo[3,4-g]indol-8-one	Human	Show
	CLK3	CLK	CMGC	6z52	A	B	11,15-dimethyl-6-(4-methylpiperazin-1-yl)-8-oxa-2,11,15,19,21,23-hexazatetracyclo[15.6.1.13,7.020,24]pentacosa-1(23),3(25),4,6,17,20(24),21-heptaen-10-one	Human	Show
	CLK3	CLK	CMGC	6rct	A	B	4-[2-methyl-1-(4-methylpiperazin-1-yl)-1-oxidanylidene-propan-2-yl]-~{n}-(6-pyridin-4-ylimidazo[1,2-a]pyridin-2-yl)benzamide	Human	Show
	CLK3	CLK	CMGC	3raw	B	B	5-(1,3-benzodioxol-5-ylmethyl)-2-(phenylamino)-4h-imidazol-4-one	Human	Show
	CLK3	CLK	CMGC	6ft7	B	A	3-phenyl-1~{h}-pyrrolo[3,4-g]indol-8-one	Human	Show
	CLK3	CLK	CMGC	6yu1	c	B	(4~{s})-7,8-bis(chloranyl)-9-methyl-1-oxidanylidene-spiro[2,4-dihydropyrido[3,4-b]indole-3,4'-piperidine]-4-carbonitrile	Human	Show
	CLK3	CLK	CMGC	6ytw	B	A	(1~{z})-1-(3-ethyl-5-methoxy-1,3-benzothiazol-2-ylidene)propan-2-one	Human	Show
	CLK3	CLK	CMGC	6ft7	B	B	3-phenyl-1~{h}-pyrrolo[3,4-g]indol-8-one	Human	Show
	CLK3	CLK	CMGC	6fyr	A	A	6-~{tert}-butyl-~{n}-[6-(1~{h}-pyrazol-4-yl)-1~{h}-imidazo[1,2-a]pyridin-2-yl]pyridine-3-carboxamide	Human	Show
	CLK3	CLK	CMGC	6z2v	A	A	(4~{s})-7,8-bis(chloranyl)-9-methyl-1-oxidanylidene-spiro[2,4-dihydropyrido[3,4-b]indole-3,4'-piperidine]-4-carbonitrile	Human	Show
	CLK3	CLK	CMGC	6z55	A	A	7,10-dioxa-13,17,18,21-tetrazatetracyclo[12.5.2.12,6.017,20]docosa-1(20),2(22),3,5,14(21),15,18-heptaene-5-carboxylic acid	Human	Show
	CLK3	CLK	CMGC	6khf	A	A	5-[(3-chlorophenyl)amino]benzo[c][2,6]naphthyridine-8-carboxylic acid	Human	Show
	CLK3	CLK	CMGC	6z54	A	A	11,15-dimethyl-6-(oxan-4-yloxy)-8-oxa-2,11,15,19,21,23-hexazatetracyclo[15.6.1.13,7.020,24]pentacosa-1(23),3(25),4,6,17,20(24),21-heptaen-10-one	Human	Show
	CLK3	CLK	CMGC	2eu9	A	B	-	Human	Show
	CLK3	CLK	CMGC	6z54	A	B	11,15-dimethyl-6-(oxan-4-yloxy)-8-oxa-2,11,15,19,21,23-hexazatetracyclo[15.6.1.13,7.020,24]pentacosa-1(23),3(25),4,6,17,20(24),21-heptaen-10-one	Human	Show
	CLK3	CLK	CMGC	6z51	A	A	n-cyclopentyl-2-[(11,15-dimethyl-10-oxo-8-oxa-2,11,15,19,21,23-hexazatetracyclo[15.6.1.13,7.020,24]pentacosa-1(23),3(25),4,6,17,20(24),21-heptaen-6-yl)oxy]acetamide	Human	Show
	CLK3	CLK	CMGC	6fyp	A	A	5-[(3-chlorophenyl)amino]benzo[c][2,6]naphthyridine-8-carboxylic acid	Human	Show
	CLK3	CLK	CMGC	2exe	A	B	-	Human	Show
	CLK3	CLK	CMGC	6rct	B	A	4-[2-methyl-1-(4-methylpiperazin-1-yl)-1-oxidanylidene-propan-2-yl]-~{n}-(6-pyridin-4-ylimidazo[1,2-a]pyridin-2-yl)benzamide	Human	Show
	CLK3	CLK	CMGC	6z55	A	B	7,10-dioxa-13,17,18,21-tetrazatetracyclo[12.5.2.12,6.017,20]docosa-1(20),2(22),3,5,14(21),15,18-heptaene-5-carboxylic acid	Human	Show
	CLK3	CLK	CMGC	6yu1	c	A	(4~{s})-7,8-bis(chloranyl)-9-methyl-1-oxidanylidene-spiro[2,4-dihydropyrido[3,4-b]indole-3,4'-piperidine]-4-carbonitrile	Human	Show
	CLK3	CLK	CMGC	6yty	A	B	(1~{z})-1-(3-ethyl-5-methoxy-1,3-benzothiazol-2-ylidene)propan-2-one	Human	Show
	CLK3	CLK	CMGC	3raw	A	A	5-(1,3-benzodioxol-5-ylmethyl)-2-(phenylamino)-4h-imidazol-4-one	Human	Show
	CLK3	CLK	CMGC	6z55	B	B	7,10-dioxa-13,17,18,21-tetrazatetracyclo[12.5.2.12,6.017,20]docosa-1(20),2(22),3,5,14(21),15,18-heptaene-5-carboxylic acid	Human	Show
	CLK3	CLK	CMGC	2wu6	A	B	5-amino-3-{[4-(aminosulfonyl)phenyl]amino}-n-(2,6-difluorophenyl)-1h-1,2,4-triazole-1-carbothioamide	Human	Show
	CLK3	CLK	CMGC	6fyp	A	B	5-[(3-chlorophenyl)amino]benzo[c][2,6]naphthyridine-8-carboxylic acid	Human	Show
	CLK3	CLK	CMGC	3raw	A	B	5-(1,3-benzodioxol-5-ylmethyl)-2-(phenylamino)-4h-imidazol-4-one	Human	Show
	CLK3	CLK	CMGC	6yu1	a	B	(4~{s})-7,8-bis(chloranyl)-9-methyl-1-oxidanylidene-spiro[2,4-dihydropyrido[3,4-b]indole-3,4'-piperidine]-4-carbonitrile	Human	Show
	CLK3	CLK	CMGC	6z55	B	A	7,10-dioxa-13,17,18,21-tetrazatetracyclo[12.5.2.12,6.017,20]docosa-1(20),2(22),3,5,14(21),15,18-heptaene-5-carboxylic acid	Human	Show
	CLK3	CLK	CMGC	6z51	A	B	n-cyclopentyl-2-[(11,15-dimethyl-10-oxo-8-oxa-2,11,15,19,21,23-hexazatetracyclo[15.6.1.13,7.020,24]pentacosa-1(23),3(25),4,6,17,20(24),21-heptaen-6-yl)oxy]acetamide	Human	Show
	CLK3	CLK	CMGC	6ytw	B	B	(1~{z})-1-(3-ethyl-5-methoxy-1,3-benzothiazol-2-ylidene)propan-2-one	Human	Show
	CLK3	CLK	CMGC	6fyr	A	B	6-~{tert}-butyl-~{n}-[6-(1~{h}-pyrazol-4-yl)-1~{h}-imidazo[1,2-a]pyridin-2-yl]pyridine-3-carboxamide	Human	Show

Division of Medicinal Chemistry - Vrije Universiteit Amsterdam