PDB-code
Search results (111 entries covering 67 PDB structures)
| # | Kinase | Family | Group | PDB | Chain | (Alternate) Model | Orthosteric ligand | Organism | Details | File |
|---|---|---|---|---|---|---|---|---|---|---|
![]() | MAP2K1 | STE7 | STE | 7f2x | A | phosphoaminophosphonic acid-adenylate ester | Human | Show | ![]() | |
![]() | MAP2K1 | STE7 | STE | 7b94 | B | phosphoaminophosphonic acid-adenylate ester | Human | Show | ![]() | |
![]() | MAP2K1 | STE7 | STE | 2p55 | A | 2-[(4-ethynyl-2-fluorophenyl)amino]-3,4-difluoro-n-(2-hydroxyethoxy)benzamide | Human | Show | ![]() | |
![]() | MAP2K1 | STE7 | STE | 7xnc | A | ~{n}-[4-[[6-(3-chloranylpyridin-4-yl)-3-methyl-1~{h}-indazol-4-yl]oxy]cyclohexyl]ethanamide | Human | Show | ![]() | |
![]() | MAP2K1 | STE7 | STE | 6v2w | B | B | phosphoaminophosphonic acid-adenylate ester | Human | Show | ![]() |
![]() | MAP2K1 | STE7 | STE | 4mne | E | A | phosphomethylphosphonic acid adenylate ester | Human | Show | ![]() |
![]() | MAP2K1 | STE7 | STE | 7m0t | B | 5-[(4-bromo-2-chlorophenyl)amino]-4-fluoro-n-(2-hydroxyethoxy)-1-methyl-1h-benzimidazole-6-carboxamide | Human | Show | ![]() | |
![]() | MAP2K1 | STE7 | STE | 4mne | A | B | phosphomethylphosphonic acid adenylate ester | Human | Show | ![]() |
![]() | MAP2K1 | STE7 | STE | 7m0v | B | A | phosphoaminophosphonic acid-adenylate ester | Human | Show | ![]() |
![]() | MAP2K1 | STE7 | STE | 4an9 | A | phosphomethylphosphonic acid adenylate ester | Human | Show | ![]() | |
![]() | MAP2K1 | STE7 | STE | 7b9l | B | A | phosphoaminophosphonic acid-adenylate ester | Human | Show | ![]() |
![]() | MAP2K1 | STE7 | STE | 6u2g | A | phosphomethylphosphonic acid adenylate ester | Human | Show | ![]() | |
![]() | MAP2K1 | STE7 | STE | 7pqv | A | A | 8-(2-chloranyl-4-methoxy-phenyl)-7-fluoranyl-1-piperidin-4-yl-imidazo[4,5-c]quinoline | Human | Show | ![]() |
![]() | MAP2K1 | STE7 | STE | 3vvh | A | A | adenosine-5'-triphosphate | Human | Show | ![]() |
![]() | MAP2K1 | STE7 | STE | 7m0v | B | B | phosphoaminophosphonic acid-adenylate ester | Human | Show | ![]() |
![]() | MAP2K1 | STE7 | STE | 3zm4 | A | 7-chloranyl-6-[(3s)-pyrrolidin-3-yl]oxy-2h-isoquinolin-1-one | Human | Show | ![]() | |
![]() | MAP2K1 | STE7 | STE | 6pp9 | B | A | phosphoaminophosphonic acid-adenylate ester | Human | Show | ![]() |
![]() | MAP2K1 | STE7 | STE | 7b3m | B | phosphoaminophosphonic acid-adenylate ester | Human | Show | ![]() | |
![]() | MAP2K1 | STE7 | STE | 7pqv | A | B | 8-(2-chloranyl-4-methoxy-phenyl)-7-fluoranyl-1-piperidin-4-yl-imidazo[4,5-c]quinoline | Human | Show | ![]() |
![]() | MAP2K1 | STE7 | STE | 7m0y | B | phosphoaminophosphonic acid-adenylate ester | Human | Show | ![]() | |
![]() | MAP2K1 | STE7 | STE | 6q0j | C | A | 5-[(2-fluoro-4-iodophenyl)amino]-n-(2-hydroxyethoxy)imidazo[1,5-a]pyridine-6-carboxamide | Human | Show | ![]() |
![]() | MAP2K1 | STE7 | STE | 3eqg | A | adenosine-5'-diphosphate | Human | Show | ![]() | |
![]() | MAP2K1 | STE7 | STE | 7mfd | B | n-(3-fluoro-4-{[4-methyl-2-oxo-7-(pyrimidin-2-yloxy)-2h-chromen-3-yl]methyl}pyridin-2-yl)-n'-methylsulfuric diamide | Human | Show | ![]() | |
![]() | MAP2K1 | STE7 | STE | 3e8n | A | adenosine-5'-triphosphate | Human | Show | ![]() | |
![]() | MAP2K1 | STE7 | STE | 7m0w | B | phosphoaminophosphonic acid-adenylate ester | Human | Show | ![]() | |
![]() | MAP2K1 | STE7 | STE | 4an3 | A | adenosine-5'-triphosphate | Human | Show | ![]() | |
![]() | MAP2K1 | STE7 | STE | 7xlp | A | (1~{r},3~{s})-3-[[6-[2-chloranyl-4-(4-methylpyrimidin-2-yl)oxy-phenyl]-3-methyl-1~{h}-indazol-4-yl]oxy]cyclohexan-1-amine | Human | Show | ![]() | |
![]() | MAP2K1 | STE7 | STE | 8chf | E | - | Human | Show | ![]() | |
![]() | MAP2K1 | STE7 | STE | 3eqc | A | A | 2-[(2-chloro-4-iodophenyl)amino]-n-{[(2r)-2,3-dihydroxypropyl]oxy}-3,4-difluorobenzamide | Human | Show | ![]() |
![]() | MAP2K1 | STE7 | STE | 3dv3 | A | B | adenosine-5'-triphosphate | Human | Show | ![]() |
![]() | MAP2K1 | STE7 | STE | 6q0j | C | B | 5-[(2-fluoro-4-iodophenyl)amino]-n-(2-hydroxyethoxy)imidazo[1,5-a]pyridine-6-carboxamide | Human | Show | ![]() |
![]() | MAP2K1 | STE7 | STE | 5yt3 | B | phosphoaminophosphonic acid-adenylate ester | Human | Show | ![]() | |
![]() | MAP2K1 | STE7 | STE | 6q0t | C | A | 5-[(2-fluoro-4-iodophenyl)amino]-n-(2-hydroxyethoxy)imidazo[1,5-a]pyridine-6-carboxamide | Human | Show | ![]() |
![]() | MAP2K1 | STE7 | STE | 4ark | A | adenosine-5'-diphosphate | Human | Show | ![]() | |
![]() | MAP2K1 | STE7 | STE | 4mne | H | B | phosphomethylphosphonic acid adenylate ester | Human | Show | ![]() |
![]() | MAP2K1 | STE7 | STE | 6q0t | C | B | 5-[(2-fluoro-4-iodophenyl)amino]-n-(2-hydroxyethoxy)imidazo[1,5-a]pyridine-6-carboxamide | Human | Show | ![]() |
![]() | MAP2K1 | STE7 | STE | 4u80 | A | phosphoaminophosphonic acid-adenylate ester | Human | Show | ![]() | |
![]() | MAP2K1 | STE7 | STE | 4u81 | A | 8-[(4-cyclopropyl-2-fluorophenyl)amino]-n-(2-hydroxyethoxy)imidazo[1,5-a]pyridine-7-carboxamide | Human | Show | ![]() | |
![]() | MAP2K1 | STE7 | STE | 3os3 | A | adenosine-5'-triphosphate | Human | Show | ![]() | |
![]() | MAP2K1 | STE7 | STE | 3sls | B | B | phosphoaminophosphonic acid-adenylate ester | Human | Show | ![]() |
![]() | MAP2K1 | STE7 | STE | 3orn | A | phosphoaminophosphonic acid-adenylate ester | Human | Show | ![]() | |
![]() | MAP2K1 | STE7 | STE | 7b9l | A | A | phosphoaminophosphonic acid-adenylate ester | Human | Show | ![]() |
![]() | MAP2K1 | STE7 | STE | 4mne | D | B | phosphomethylphosphonic acid adenylate ester | Human | Show | ![]() |
![]() | MAP2K1 | STE7 | STE | 7umb | B | phosphoaminophosphonic acid-adenylate ester | Human | Show | ![]() | |
![]() | MAP2K1 | STE7 | STE | 3eqb | A | B | adenosine-5'-triphosphate | Human | Show | ![]() |
![]() | MAP2K1 | STE7 | STE | 4anb | A | [3-(aminomethyl)-3-oxidanyl-azetidin-1-yl]-[3,4-bis(fluoranyl)-2-[(2-fluoranyl-4-iodanyl-phenyl)amino]phenyl]methanone | Human | Show | ![]() | |
![]() | MAP2K1 | STE7 | STE | 3zlw | A | (1r)-1-hydroxy-1-methyl-2,3,6,7-tetrahydro-1h,5h-pyrido[3,2,1-ij]quinolin-5-one | Human | Show | ![]() | |
![]() | MAP2K1 | STE7 | STE | 6v2w | B | A | phosphoaminophosphonic acid-adenylate ester | Human | Show | ![]() |
![]() | MAP2K1 | STE7 | STE | 4mne | E | B | phosphomethylphosphonic acid adenylate ester | Human | Show | ![]() |
![]() | MAP2K1 | STE7 | STE | 3vvh | C | A | adenosine-5'-triphosphate | Human | Show | ![]() |
![]() | MAP2K1 | STE7 | STE | 4mne | A | A | phosphomethylphosphonic acid adenylate ester | Human | Show | ![]() |
![]() | MAP2K1 | STE7 | STE | 5yt3 | A | phosphoaminophosphonic acid-adenylate ester | Human | Show | ![]() | |
![]() | MAP2K1 | STE7 | STE | 3eqc | A | B | 2-[(2-chloro-4-iodophenyl)amino]-n-{[(2r)-2,3-dihydroxypropyl]oxy}-3,4-difluorobenzamide | Human | Show | ![]() |
![]() | MAP2K1 | STE7 | STE | 7b9l | B | B | phosphoaminophosphonic acid-adenylate ester | Human | Show | ![]() |
![]() | MAP2K1 | STE7 | STE | 3eqb | A | A | adenosine-5'-triphosphate | Human | Show | ![]() |
![]() | MAP2K1 | STE7 | STE | 3vvh | A | B | adenosine-5'-triphosphate | Human | Show | ![]() |
![]() | MAP2K1 | STE7 | STE | 5hze | A | A | (3s,4r,8s,9s,11e)-8,9,16-trihydroxy-3,4-dimethyl-14-(methylamino)-3,4,5,6,9,10-hexahydro-1h-2-benzoxacyclotetradecine-1,7(8h)-dione | Human | Show | ![]() |
![]() | MAP2K1 | STE7 | STE | 3vvh | C | B | adenosine-5'-triphosphate | Human | Show | ![]() |
![]() | MAP2K1 | STE7 | STE | 3dy7 | A | adenosine-5'-triphosphate | Human | Show | ![]() | |
![]() | MAP2K1 | STE7 | STE | 3mbl | A | B | adenosine-5'-diphosphate | Human | Show | ![]() |
![]() | MAP2K1 | STE7 | STE | 8dgs | B | A | phosphothiophosphoric acid-adenylate ester | Human | Show | ![]() |
![]() | MAP2K1 | STE7 | STE | 8dgt | B | A | phosphothiophosphoric acid-adenylate ester | Human | Show | ![]() |
![]() | MAP2K1 | STE7 | STE | 8dgs | B | B | phosphothiophosphoric acid-adenylate ester | Human | Show | ![]() |
![]() | MAP2K1 | STE7 | STE | 8dgt | B | B | phosphothiophosphoric acid-adenylate ester | Human | Show | ![]() |
![]() | MAP2K1 | STE7 | STE | 3v04 | A | 4-[(2-fluoro-4-iodophenyl)amino]-n-(2-hydroxyethoxy)-1h-indazole-5-carboxamide | Human | Show | ![]() | |
![]() | MAP2K1 | STE7 | STE | 6nyb | B | adenosine-5'-diphosphate | Human | Show | ![]() | |
![]() | MAP2K1 | STE7 | STE | 6q0j | D | B | 5-[(2-fluoro-4-iodophenyl)amino]-n-(2-hydroxyethoxy)imidazo[1,5-a]pyridine-6-carboxamide | Human | Show | ![]() |
![]() | MAP2K1 | STE7 | STE | 5yt3 | D | phosphoaminophosphonic acid-adenylate ester | Human | Show | ![]() | |
![]() | MAP2K1 | STE7 | STE | 4mne | D | A | phosphomethylphosphonic acid adenylate ester | Human | Show | ![]() |
![]() | MAP2K1 | STE7 | STE | 3sls | B | A | phosphoaminophosphonic acid-adenylate ester | Human | Show | ![]() |
![]() | MAP2K1 | STE7 | STE | 7m0x | B | A | phosphoaminophosphonic acid-adenylate ester | Human | Show | ![]() |
![]() | MAP2K1 | STE7 | STE | 3sls | A | A | phosphoaminophosphonic acid-adenylate ester | Human | Show | ![]() |
![]() | MAP2K1 | STE7 | STE | 4mne | H | A | phosphomethylphosphonic acid adenylate ester | Human | Show | ![]() |
![]() | MAP2K1 | STE7 | STE | 7b7r | A | phosphoaminophosphonic acid-adenylate ester | Human | Show | ![]() | |
![]() | MAP2K1 | STE7 | STE | 6pp9 | B | B | phosphoaminophosphonic acid-adenylate ester | Human | Show | ![]() |
![]() | MAP2K1 | STE7 | STE | 3dv3 | A | A | adenosine-5'-triphosphate | Human | Show | ![]() |
![]() | MAP2K1 | STE7 | STE | 4lmn | A | phosphoaminophosphonic acid-adenylate ester | Human | Show | ![]() | |
![]() | MAP2K1 | STE7 | STE | 3eqf | A | k-252a | Human | Show | ![]() | |
![]() | MAP2K1 | STE7 | STE | 3wig | A | phosphoaminophosphonic acid-adenylate ester | Human | Show | ![]() | |
![]() | MAP2K1 | STE7 | STE | 1s9j | A | adenosine-5'-triphosphate | Human | Show | ![]() | |
![]() | MAP2K1 | STE7 | STE | 3pp1 | A | B | adenosine-5'-triphosphate | Human | Show | ![]() |
![]() | MAP2K1 | STE7 | STE | 3sls | A | B | phosphoaminophosphonic acid-adenylate ester | Human | Show | ![]() |
![]() | MAP2K1 | STE7 | STE | 3vvh | B | A | adenosine-5'-triphosphate | Human | Show | ![]() |
![]() | MAP2K1 | STE7 | STE | 7b7r | B | phosphoaminophosphonic acid-adenylate ester | Human | Show | ![]() | |
![]() | MAP2K1 | STE7 | STE | 5eym | A | B | 3-[(3~{z})-3-[[[4-[(dimethylamino)methyl]phenyl]amino]-phenyl-methylidene]-2-oxidanylidene-1~{h}-indol-6-yl]-~{n}-ethyl-prop-2-ynamide | Human | Show | ![]() |
![]() | MAP2K1 | STE7 | STE | 3eqd | A | phosphothiophosphoric acid-adenylate ester | Human | Show | ![]() | |
![]() | MAP2K1 | STE7 | STE | 5bx0 | A | ethyl 2h-indazole-5-carboxylate | Human | Show | ![]() | |
![]() | MAP2K1 | STE7 | STE | 4u7z | A | 5-[(4-bromo-2-chlorophenyl)amino]-4-fluoro-n-(2-hydroxyethoxy)-1-methyl-1h-benzimidazole-6-carboxamide | Human | Show | ![]() | |
![]() | MAP2K1 | STE7 | STE | 3zly | A | 3-amino-1h-indazole-4-carbonitrile | Human | Show | ![]() | |
![]() | MAP2K1 | STE7 | STE | 5hze | A | B | (3s,4r,8s,9s,11e)-8,9,16-trihydroxy-3,4-dimethyl-14-(methylamino)-3,4,5,6,9,10-hexahydro-1h-2-benzoxacyclotetradecine-1,7(8h)-dione | Human | Show | ![]() |
![]() | MAP2K1 | STE7 | STE | 6q0j | D | A | 5-[(2-fluoro-4-iodophenyl)amino]-n-(2-hydroxyethoxy)imidazo[1,5-a]pyridine-6-carboxamide | Human | Show | ![]() |
![]() | MAP2K1 | STE7 | STE | 3w8q | A | phosphothiophosphoric acid-adenylate ester | Human | Show | ![]() | |
![]() | MAP2K1 | STE7 | STE | 3vvh | B | B | adenosine-5'-triphosphate | Human | Show | ![]() |
![]() | MAP2K1 | STE7 | STE | 3eqi | A | adenosine-5'-diphosphate | Human | Show | ![]() | |
![]() | MAP2K1 | STE7 | STE | 4an2 | A | B | [3,4-bis(fluoranyl)-2-[(2-fluoranyl-4-iodanyl-phenyl)amino]phenyl]-[3-oxidanyl-3-[(2s)-piperidin-2-yl]azetidin-1-yl]methanone | Human | Show | ![]() |
![]() | MAP2K1 | STE7 | STE | 3eqh | A | (2z)-bis{amino[(2-aminophenyl)sulfanyl]methylidene}butanedinitrile | Human | Show | ![]() | |
![]() | MAP2K1 | STE7 | STE | 3pp1 | A | A | adenosine-5'-triphosphate | Human | Show | ![]() |
![]() | MAP2K1 | STE7 | STE | 7b3m | A | phosphoaminophosphonic acid-adenylate ester | Human | Show | ![]() | |
![]() | MAP2K1 | STE7 | STE | 3zls | A | 1h-pyrrolo[2,3-b]pyridine-3-carboxylic acid | Human | Show | ![]() | |
![]() | MAP2K1 | STE7 | STE | 4an2 | A | A | [3,4-bis(fluoranyl)-2-[(2-fluoranyl-4-iodanyl-phenyl)amino]phenyl]-[3-oxidanyl-3-[(2s)-piperidin-2-yl]azetidin-1-yl]methanone | Human | Show | ![]() |
![]() | MAP2K1 | STE7 | STE | 3v01 | A | n-{[(2r)-2,3-dihydroxypropyl]oxy}-3-[(2-fluoro-4-iodophenyl)amino]furo[3,2-c]pyridine-2-carboxamide | Human | Show | ![]() | |
![]() | MAP2K1 | STE7 | STE | 7m0z | B | phosphoaminophosphonic acid-adenylate ester | Human | Show | ![]() | |
![]() | MAP2K1 | STE7 | STE | 5eym | B | A | 3-[(3~{z})-3-[[[4-[(dimethylamino)methyl]phenyl]amino]-phenyl-methylidene]-2-oxidanylidene-1~{h}-indol-6-yl]-~{n}-ethyl-prop-2-ynamide | Human | Show | ![]() |
![]() | MAP2K1 | STE7 | STE | 3zlx | A | 7-choro-6-[(3r)-pyrrolidin-3-ylmethoxy]isoquinolin-1(2h)-one | Human | Show | ![]() | |
![]() | MAP2K1 | STE7 | STE | 7m0u | B | 5-[(4-bromo-2-fluorophenyl)amino]-4-fluoro-n-(2-hydroxyethoxy)-1-methyl-1h-benzimidazole-6-carboxamide | Human | Show | ![]() | |
![]() | MAP2K1 | STE7 | STE | 5yt3 | C | phosphoaminophosphonic acid-adenylate ester | Human | Show | ![]() | |
![]() | MAP2K1 | STE7 | STE | 3mbl | A | A | adenosine-5'-diphosphate | Human | Show | ![]() |
![]() | MAP2K1 | STE7 | STE | 7m0x | B | B | phosphoaminophosphonic acid-adenylate ester | Human | Show | ![]() |
![]() | MAP2K1 | STE7 | STE | 5eym | B | B | 3-[(3~{z})-3-[[[4-[(dimethylamino)methyl]phenyl]amino]-phenyl-methylidene]-2-oxidanylidene-1~{h}-indol-6-yl]-~{n}-ethyl-prop-2-ynamide | Human | Show | ![]() |
![]() | MAP2K1 | STE7 | STE | 5eym | A | A | 3-[(3~{z})-3-[[[4-[(dimethylamino)methyl]phenyl]amino]-phenyl-methylidene]-2-oxidanylidene-1~{h}-indol-6-yl]-~{n}-ethyl-prop-2-ynamide | Human | Show | ![]() |
![]() | MAP2K1 | STE7 | STE | 7b9l | A | B | phosphoaminophosphonic acid-adenylate ester | Human | Show | ![]() |


