PDB-code
Search results (19 entries covering 10 PDB structures)
| # | Kinase | Family | Group | PDB | Chain | (Alternate) Model | Orthosteric ligand | Organism | Details | File |
|---|---|---|---|---|---|---|---|---|---|---|
 | MAP3K12 (DLK) | MLK | TKL | 8deg | A | methyl (1s,4s)-5-{(4p)-4-[5-amino-6-(difluoromethoxy)pyrazin-2-yl]-6-[(1r,4r)-2-azabicyclo[2.1.1]hexan-2-yl]pyridin-2-yl}-2,5-diazabicyclo[2.2.1]heptane-2-carboxylate | Human | Show |  | |
| MAP3K12 (DLK) | MLK | TKL | 5ceo | A | A | 2-[[6-[3,3-bis(fluoranyl)pyrrolidin-1-yl]-4-[1-(oxetan-3-yl)piperidin-4-yl]pyridin-2-yl]amino]pyridine-4-carbonitrile | Human | Show | |
| MAP3K12 (DLK) | MLK | TKL | 8our | A | A | 5-[1-(3-morpholin-4-yl-1-bicyclo[1.1.1]pentanyl)-2-propan-2-yl-imidazol-4-yl]-3-(trifluoromethyloxy)pyridin-2-amine | Human | Show | |
| MAP3K12 (DLK) | MLK | TKL | 8out | A | B | (1r)-1-[4-[6-azanyl-5-(trifluoromethyloxy)pyridin-3-yl]-1-(3-fluoranyl-1-bicyclo[1.1.1]pentanyl)imidazol-2-yl]-2,2,2-tris(fluoranyl)ethanol | Human | Show | |
| MAP3K12 (DLK) | MLK | TKL | 8out | A | A | (1r)-1-[4-[6-azanyl-5-(trifluoromethyloxy)pyridin-3-yl]-1-(3-fluoranyl-1-bicyclo[1.1.1]pentanyl)imidazol-2-yl]-2,2,2-tris(fluoranyl)ethanol | Human | Show | |
| MAP3K12 (DLK) | MLK | TKL | 5ceq | A | A | 2-[[1-cyclopentyl-5-[1-(oxetan-3-yl)piperidin-4-yl]pyrazol-3-yl]amino]pyridine-4-carbonitrile | Human | Show | |
| MAP3K12 (DLK) | MLK | TKL | 5cep | A | A | n-(5-piperidin-4-yl-1-propan-2-yl-pyrazol-3-yl)-4-(trifluoromethyl)pyridin-2-amine | Human | Show | |
| MAP3K12 (DLK) | MLK | TKL | 8ous | A | B | (1s)-1-[4-[6-azanyl-5-(trifluoromethyloxy)pyridin-3-yl]-1-(3-morpholin-4-yl-1-bicyclo[1.1.1]pentanyl)imidazol-2-yl]-2-methyl-propan-1-ol | Human | Show | |
| MAP3K12 (DLK) | MLK | TKL | 8our | A | B | 5-[1-(3-morpholin-4-yl-1-bicyclo[1.1.1]pentanyl)-2-propan-2-yl-imidazol-4-yl]-3-(trifluoromethyloxy)pyridin-2-amine | Human | Show | |
| MAP3K12 (DLK) | MLK | TKL | 5cen | A | A | - | Human | Show | |
| MAP3K12 (DLK) | MLK | TKL | 5ceq | A | B | 2-[[1-cyclopentyl-5-[1-(oxetan-3-yl)piperidin-4-yl]pyrazol-3-yl]amino]pyridine-4-carbonitrile | Human | Show | |
| MAP3K12 (DLK) | MLK | TKL | 5cen | A | B | - | Human | Show | |
| MAP3K12 (DLK) | MLK | TKL | 5vo2 | A | B | 5-{5-[1-(oxetan-3-yl)piperidin-4-yl]-1-(propan-2-yl)-1h-pyrazol-3-yl}-3-(trifluoromethyl)pyridin-2-amine | Human | Show | |
| MAP3K12 (DLK) | MLK | TKL | 8ous | A | A | (1s)-1-[4-[6-azanyl-5-(trifluoromethyloxy)pyridin-3-yl]-1-(3-morpholin-4-yl-1-bicyclo[1.1.1]pentanyl)imidazol-2-yl]-2-methyl-propan-1-ol | Human | Show | |
| MAP3K12 (DLK) | MLK | TKL | 5vo2 | A | A | 5-{5-[1-(oxetan-3-yl)piperidin-4-yl]-1-(propan-2-yl)-1h-pyrazol-3-yl}-3-(trifluoromethyl)pyridin-2-amine | Human | Show | |
| MAP3K12 (DLK) | MLK | TKL | 5vo1 | A | B | 5-{5-[(1r,5s,6r)-3-(oxetan-3-yl)-3-azabicyclo[3.1.0]hexan-6-yl]-1-(propan-2-yl)-1h-pyrazol-3-yl}-3-(trifluoromethyl)pyridin-2-amine | Human | Show | |
| MAP3K12 (DLK) | MLK | TKL | 5vo1 | A | A | 5-{5-[(1r,5s,6r)-3-(oxetan-3-yl)-3-azabicyclo[3.1.0]hexan-6-yl]-1-(propan-2-yl)-1h-pyrazol-3-yl}-3-(trifluoromethyl)pyridin-2-amine | Human | Show | |
| MAP3K12 (DLK) | MLK | TKL | 5ceo | A | B | 2-[[6-[3,3-bis(fluoranyl)pyrrolidin-1-yl]-4-[1-(oxetan-3-yl)piperidin-4-yl]pyridin-2-yl]amino]pyridine-4-carbonitrile | Human | Show | |
| MAP3K12 (DLK) | MLK | TKL | 5cep | A | B | n-(5-piperidin-4-yl-1-propan-2-yl-pyrazol-3-yl)-4-(trifluoromethyl)pyridin-2-amine | Human | Show | |
