PDB-code
Search results (30 entries covering 23 PDB structures)
| # | Kinase | Family | Group | PDB | Chain | (Alternate) Model | Orthosteric ligand | Organism | Details | File |
|---|---|---|---|---|---|---|---|---|---|---|
 | MAP3K7 (TAK1) | MLK | TKL | 5gjf | A | n-(2-isopropoxy-4-(4-methylpiperazine-1-carbonyl)phenyl)-2-(3-(3-phenylureido)phenyl)thiazole-4-carboxamide | Human | Show |  | |
| MAP3K7 (TAK1) | MLK | TKL | 5gjg | A | n-(2-isopropoxy-4-(4-methylpiperazine-1-carbonyl)phenyl)-2-(3-(phenylcarbamoyl)phenyl)thiazole-4-carboxamide | Human | Show | | |
| MAP3K7 (TAK1) | MLK | TKL | 5jgb | A | n-(2-methoxy-4-{[3-(4-methylpiperazin-1-yl)propyl]carbamoyl}phenyl)-4-oxo-3,4-dihydrothieno[3,2-d]pyrimidine-7-carboxamide | Human | Show | | |
| MAP3K7 (TAK1) | MLK | TKL | 8gw3 | A | - | Human | Show | | |
| MAP3K7 (TAK1) | MLK | TKL | 5v5n | A | A | n~1~-(1-propyl-1,3-dihydro-2h-benzimidazol-2-ylidene)benzene-1,3-dicarboxamide | Human | Show | |
| MAP3K7 (TAK1) | MLK | TKL | 4l52 | A | A | 1-(4-{4-[7-amino-2-(1,2,3-benzothiadiazol-7-yl)furo[2,3-c]pyridin-4-yl]-1h-pyrazol-1-yl}piperidin-1-yl)ethanone | Human | Show | |
| MAP3K7 (TAK1) | MLK | TKL | 5gjd | A | 1-(4-((1h-pyrrolo[2,3-b]pyridin-4-yl)oxy)phenyl)-3-(5-(4-methylpiperazin-1-yl)naphthalen-2-yl)urea | Human | Show | | |
| MAP3K7 (TAK1) | MLK | TKL | 5v5n | A | B | n~1~-(1-propyl-1,3-dihydro-2h-benzimidazol-2-ylidene)benzene-1,3-dicarboxamide | Human | Show | |
| MAP3K7 (TAK1) | MLK | TKL | 5j7s | A | n-{2-[(5-chloro-2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}pyrimidin-4-yl)amino]phenyl}propanamide | Human | Show | | |
| MAP3K7 (TAK1) | MLK | TKL | 2eva | A | B | adenosine | Human | Show | |
| MAP3K7 (TAK1) | MLK | TKL | 5e7r | A | 2-chloro-n-{2-[(5-chloro-2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}pyrimidin-4-yl)oxy]phenyl}acetamide | Human | Show | | |
| MAP3K7 (TAK1) | MLK | TKL | 7nth | A | A | 2-[[5-[[2-[bis(fluoranyl)methoxy]phenyl]methyl-[(2~{r})-1-(methylamino)-1-oxidanylidene-propan-2-yl]carbamoyl]-1~{h}-imidazol-2-yl]carbonyl]isoindole-5-carboxamide | Human | Show | |
| MAP3K7 (TAK1) | MLK | TKL | 2yiy | A | (1e)-1-[5-tert-butyl-2-(3-fluorophenyl)-1h-pyrazol-3-ylidene]-3-(4-pyridin-3-yloxyphenyl)urea | Human | Show | | |
| MAP3K7 (TAK1) | MLK | TKL | 4l53 | A | A | trans-4-{4-[7-amino-2-(1,2,3-benzothiadiazol-7-yl)-3-chlorofuro[2,3-c]pyridin-4-yl]-1h-pyrazol-1-yl}cyclohexanol | Human | Show | |
| MAP3K7 (TAK1) | MLK | TKL | 5jh6 | A | 2-[(5-chloro-2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}pyrimidin-4-yl)amino]phenyl prop-2-enoate | Human | Show | | |
| MAP3K7 (TAK1) | MLK | TKL | 7nti | A | B | ~{n}-[[2-[bis(fluoranyl)methoxy]phenyl]methyl]-~{n}-[2-(methylamino)-2-oxidanylidene-ethyl]-2-pyrrolidin-1-ylcarbonyl-1~{h}-imidazole-4-carboxamide | Human | Show | |
| MAP3K7 (TAK1) | MLK | TKL | 4l53 | A | B | trans-4-{4-[7-amino-2-(1,2,3-benzothiadiazol-7-yl)-3-chlorofuro[2,3-c]pyridin-4-yl]-1h-pyrazol-1-yl}cyclohexanol | Human | Show | |
| MAP3K7 (TAK1) | MLK | TKL | 4l3p | A | 2-(1-benzothiophen-7-yl)-4-[1-(piperidin-4-yl)-1h-pyrazol-4-yl]furo[2,3-c]pyridin-7-amine | Human | Show | | |
| MAP3K7 (TAK1) | MLK | TKL | 4gs6 | A | B | (3s,5z,8s,9s,11e)-8,9,16-trihydroxy-14-methoxy-3-methyl-3,4,9,10-tetrahydro-1h-2-benzoxacyclotetradecine-1,7(8h)-dione | Human | Show | |
| MAP3K7 (TAK1) | MLK | TKL | 4o91 | A | n-{4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}-4-methyl-3-(1h-pyrrolo[2,3-b]pyridin-4-yloxy)benzamide | Human | Show | | |
| MAP3K7 (TAK1) | MLK | TKL | 4l52 | A | B | 1-(4-{4-[7-amino-2-(1,2,3-benzothiadiazol-7-yl)furo[2,3-c]pyridin-4-yl]-1h-pyrazol-1-yl}piperidin-1-yl)ethanone | Human | Show | |
| MAP3K7 (TAK1) | MLK | TKL | 2eva | A | A | adenosine | Human | Show | |
| MAP3K7 (TAK1) | MLK | TKL | 7nti | A | A | ~{n}-[[2-[bis(fluoranyl)methoxy]phenyl]methyl]-~{n}-[2-(methylamino)-2-oxidanylidene-ethyl]-2-pyrrolidin-1-ylcarbonyl-1~{h}-imidazole-4-carboxamide | Human | Show | |
| MAP3K7 (TAK1) | MLK | TKL | 5jgd | A | n-(2-isopropoxy-3-(4-methylpiperazine-1-carbonyl)phenyl)-4-oxo-3,4-dihydrothieno[3,2-d]pyrimidine-7-carboxamide | Human | Show | | |
| MAP3K7 (TAK1) | MLK | TKL | 5jga | A | n-[5-(4-methylpiperazine-1-carbonyl)[1,1'-biphenyl]-2-yl]-4-oxo-3,4-dihydrothieno[3,2-d]pyrimidine-7-carboxamide | Human | Show | | |
| MAP3K7 (TAK1) | MLK | TKL | 5j8i | A | n-{2-[(5-chloro-2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}pyrimidin-4-yl)oxy]phenyl}prop-2-enamide | Human | Show | | |
| MAP3K7 (TAK1) | MLK | TKL | 5jk3 | A | ~{n}-[2-[5-chloranyl-2-[(1-methylpyrazol-4-yl)amino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide | Human | Show | | |
| MAP3K7 (TAK1) | MLK | TKL | 4gs6 | A | A | (3s,5z,8s,9s,11e)-8,9,16-trihydroxy-14-methoxy-3-methyl-3,4,9,10-tetrahydro-1h-2-benzoxacyclotetradecine-1,7(8h)-dione | Human | Show | |
| MAP3K7 (TAK1) | MLK | TKL | 5j9l | A | n-(4-((2-((4-(4-methylpiperazin-1-yl)phenyl)amino)-7h-pyrrolo[2,3-d]pyrimidin-4-yl)oxy)phenyl)acrylamide | Human | Show | | |
| MAP3K7 (TAK1) | MLK | TKL | 7nth | A | B | 2-[[5-[[2-[bis(fluoranyl)methoxy]phenyl]methyl-[(2~{r})-1-(methylamino)-1-oxidanylidene-propan-2-yl]carbamoyl]-1~{h}-imidazol-2-yl]carbonyl]isoindole-5-carboxamide | Human | Show | |
