Aurora kinase A
Kinase structure
Kinase:AURKA (AurA)
Family:Aur
Group:Other
Species:HUMAN
IUPHAR/BPS ID:1936
PDB:6CPE
sc-PDB:
KIDFamMap:Search
Release date:2018-06-27
PubMed: 29901437
Chain:A
(Alternate) Model:B
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The orthosteric binding pocket


More entries for 6CPE
6CPEAlternative model: AChain: A


Structural information
DFG conformation:in
αC-helix conformation:in
G-rich loop angle (distance):59.7° (17.2Å)
G-rich loop rotation:72.2°
Quality Score:8
Resolution:2.45 Å
Missing Residues:0
Missing Atoms:31

Allosteric Ligand
Allosteric ligand:P4G
2D structure of the allostericligand
Pocket alignment
Uniprot sequence:RPLGKGKFGNVYLLALKVLQLRREVEIQSHLRPNILRLYGYYLILEYAPLGTVYRELQKYCHSKRVIHRDIKPENLLLIADFGWS
Sequence structure:RPLGKGKFGNVYLLALKVLQLRREVEIQSHLRPNILRLYGYYLILEYAPLGTVYRELQKYCHSKRVIHRDIKPENLLLIADFGWS