Insulin like growth factor 1 receptor
Kinase structure
Kinase:IGF1R
Family:InsR
Group:TK
Species:HUMAN
IUPHAR/BPS ID:1801
PDB:1M7N
sc-PDB:
KIDFamMap:Search
Release date:2003-01-07
PubMed: 12138114
Chain:A
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The orthosteric binding pocket


More entries for 1M7N
1M7NChain: B


Structural information
DFG conformation:out-like
αC-helix conformation:in
G-rich loop angle (distance):66.2° (19.3Å)
G-rich loop rotation:67°
Quality Score:7.6
Resolution:2.7 Å
Missing Residues:0
Missing Atoms:0
Ligand binding mode
Waters
Cluster
I1
Ligand
No
Protein
Yes

Pocket alignment
Uniprot sequence:RELGQGSFGMVYEVAIKTVEFLNEASVMKEFN-HVVRLLGVLVIMELMTRGDLKSYLRSYLNANKFVHRDLAARNCMVIGDFGMT
Sequence structure:RELGQGSFGMVYEVAIKTVEFLNEASVMKEFN_HVVRLLGVLVIMELMTRGDLKSYLRSYLNANKFVHRDLAARNCMVIGDFGMT