PDB-code
| Kinase structure | |
| Kinase: | IGF1R |
| Family: | InsR |
| Group: | TK |
| Species: | HUMAN |
| IUPHAR/BPS ID: | 1801 |
| PDB: | 3LW0 |
| sc-PDB: | |
| KIDFamMap: | Search |
| Release date: | 2010-09-29 |
| PubMed: | 24900194 |
| Chain: | C |
| (Alternate) Model: | B |
| More entries for 3LW0 | |||||
| 3LW0 | Alternative model: | A | Chain: | A | |
| 3LW0 | Alternative model: | A | Chain: | B | |
| 3LW0 | Alternative model: | A | Chain: | C | |
| 3LW0 | Alternative model: | A | Chain: | D | |
| 3LW0 | Alternative model: | B | Chain: | A | |
| 3LW0 | Alternative model: | B | Chain: | B | |
| 3LW0 | Alternative model: | B | Chain: | D | |
| Structural information | |
| DFG conformation: | out |
| αC-helix conformation: | in |
| G-rich loop angle (distance): | 63.6° (18.6Å) |
| G-rich loop rotation: | 74.7° |
| Quality Score: | 7.2 |
| Resolution: | 1.79 Å |
| Missing Residues: | 0 |
| Missing Atoms: | 0 |
| Ligand binding mode | ||||
| Waters | ||||
| Cluster I1 I4 I9 I10 | Ligand No No No No | Protein Yes Yes Yes Yes | ||
| Allosteric Ligand | |
| Allosteric ligand: | CCX |
 | |
| Pocket alignment | |
| Uniprot sequence: | RELGQGSFGMVYEVAIKTVEFLNEASVMKEFN-HVVRLLGVLVIMELMTRGDLKSYLRSYLNANKFVHRDLAARNCMVIGDFGMT |
| Sequence structure: | RELGQGSFGMVYEVAIKTVEFLNEASVMKEFN_HVVRLLGVLVIMELMTRGDLKSYLRSYLNANKFVHRDLAARNCMVIGDFGMT |
