Version: 3.2
Updated: 29-Oct-2025
Protein kinase cAMP-activated catalytic subunit alpha
Kinase structure
Kinase:PRKACA (PKACa)
Family:PKA
Group:AGC
Species:HUMAN
IUPHAR/BPS ID:1476
PDB:6BYS
sc-PDB:
KIDFamMap:Search
Release date:2019-04-03
PubMed: 30905674
Chain:E
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The orthosteric binding pocket


More entries for 6BYS
6BYSChain: A
6BYSChain: C
6BYSChain: G


Structural information
DFG conformation:in
αC-helix conformation:in
G-rich loop angle (distance):46.2° (14Å)
G-rich loop rotation:66.4°
Quality Score:8
Resolution:4.75 Å
Missing Residues:0
Missing Atoms:0

Pocket alignment
Uniprot sequence:KTLGTGSFGRVMLYAMKILHTLNEKRILQAVNPFLVKLEFSYMVMEYVPGGEMFSHLRRYLHSLDLIYRDLKPENLLIVTDFGFA
Sequence structure:KTLGTGSFGRVMLYAMKILHTLNEKRILQAVNPFLVKLEFSYMVMEYVPGGEMFSHLRRYLHSLDLIYRDLKPENLLIVTDFGFA