Mitogen-activated protein kinase 14
Kinase structure
Kinase:Mapk14 (p38a)
Family:MAPK
Group:CMGC
Species:MOUSE
PDB:6SO4
sc-PDB:
KIDFamMap:Search
Release date:2019-09-11
PubMed: 32543856
Chain:A
(Alternate) Model:B
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The orthosteric binding pocket


More entries for 6SO4
6SO4Alternative model: AChain: A


Structural information
DFG conformation:in
αC-helix conformation:in
G-rich loop angle (distance):-
G-rich loop rotation:-
Quality Score:6.4
Resolution:1.51 Å
Missing Residues:4
Missing Atoms:21
Ligand binding mode
Waters
Cluster
I2
I3
I4
I5
Ligand
No
No
No
No
Protein
No
No
Yes
Yes

Allosteric Ligand
Allosteric ligand:LO8
2D structure of the allostericligand
Pocket alignment
Uniprot sequence:SPVGSGAYGSVCAVAVKKLRTYRELRLLKHMKENVIGLLDVYLVTHLMG-ADLNNIVKCYIHSADIIHRDLKPSNLAVILDFGLA
Sequence structure:SPVGS_AYGSVCAVAVKKLRTYRELRLLKHMKENVIGLLDVYLVTHLMG_ADLNNIV__YIHSADIIHRDLKPSNLAVILDFGL_