Dual specificity tyrosine phosphorylation regulated kinase 1A
Kinase structure
Kinase:DYRK1A
Family:DYRK
Group:CMGC
Species:HUMAN
IUPHAR/BPS ID:2009
PDB:6T6A
sc-PDB:
KIDFamMap:Search
Release date:2019-12-04
PubMed: 31766108
Chain:D
(Alternate) Model:B
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The orthosteric binding pocket


More entries for 6T6A
6T6AAlternative model: AChain: A
6T6AAlternative model: AChain: B
6T6AAlternative model: AChain: C
6T6AAlternative model: AChain: D
6T6AAlternative model: BChain: A
6T6AAlternative model: BChain: B
6T6AAlternative model: BChain: C


Structural information
DFG conformation:in
αC-helix conformation:in
G-rich loop angle (distance):49.5° (15.5Å)
G-rich loop rotation:66.4°
Quality Score:8
Resolution:2.8 Å
Missing Residues:0
Missing Atoms:0
Ligand binding mode
Waters
Cluster
I11
Ligand
No
Protein
No

Pocket alignment
Uniprot sequence:SLIGKGSFGQVVKVAIKIIQAQIEVRLLELMNYYIVHLKRHCLVFEMLS-YNLYDLLRNATPELSIIHCDLKPENILLIVDFGSS
Sequence structure:SLIGKGSFGQVVKVAIKIIQAQIEVRLLELMNYYIVHLKRHCLVFEMLS_YNLYDLLRNATPELSIIHCDLKPENILLIVDFGSS