Colony stimulating factor 1 receptor
Kinase structure
Kinase:CSF1R (FMS)
Family:PDGFR
Group:TK
Species:HUMAN
IUPHAR/BPS ID:1806
PDB:2OGV
sc-PDB:
KIDFamMap:Search
Release date:2007-02-06
PubMed: 17292918
Chain:A
Click to open a 3D viewer
The orthosteric binding pocket
Structural information
DFG conformation:out
αC-helix conformation:in
G-rich loop angle (distance):64° (19.2Å)
G-rich loop rotation:46.4°
Quality Score:7.4
Resolution:2.7 Å
Missing Residues:0
Missing Atoms:0
Ligand binding mode
Waters
Cluster
I1
I5
Ligand
No
No
Protein
Yes
Yes

Pocket alignment
Uniprot sequence:KTLGAGAFGKVVEVAVKMLALMSELKIMSHLGENIVNLLGALVITEYCCYGDLLNFLRRFLASKNCIHRDVAARNVLLIGDFGLA
Sequence structure:KTLGAGAFGKVVEVAVKMLALMSELKIMSHLGENIVNLLGALVITEYCCYGDLLNFLRRFLASKNCIHRDVAARNVLLIGDFGLA