Mitogen-activated protein kinase 14
Kinase structure
Kinase:Mapk14 (p38a)
Family:MAPK
Group:CMGC
Species:MOUSE
PDB:5R9G
sc-PDB:
KIDFamMap:Search
Release date:2020-07-22
PubMed: 32543856
Chain:A
(Alternate) Model:B
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The orthosteric binding pocket


More entries for 5R9G
5R9GAlternative model: AChain: A


Structural information
DFG conformation:in
αC-helix conformation:in
G-rich loop angle (distance):63.9° (18.9Å)
G-rich loop rotation:46.4°
Quality Score:8
Resolution:1.73 Å
Missing Residues:0
Missing Atoms:21
Ligand binding mode
Waters
Cluster
I2
I3
I4
I5
Ligand
No
No
No
No
Protein
No
No
Yes
Yes

Allosteric Ligand
Allosteric ligand:RGY
2D structure of the allostericligand
Pocket alignment
Uniprot sequence:SPVGSGAYGSVCAVAVKKLRTYRELRLLKHMKENVIGLLDVYLVTHLMG-ADLNNIVKCYIHSADIIHRDLKPSNLAVILDFGLA
Sequence structure:SPVGSGAYGSVCAVAVKKLRTYRELRLLKHMKENVIGLLDVYLVTHLMG_ADLNNIVKCYIHSADIIHRDLKPSNLAVILDFGLA