Mitogen-activated protein kinase kinase 7
Kinase structure
Kinase:MAP2K7
Family:STE7
Group:STE
Species:HUMAN
IUPHAR/BPS ID:2068
PDB:6YZ4
sc-PDB:
KIDFamMap:Search
Release date:2020-08-11
PubMed: 32783966
Chain:A
(Alternate) Model:B
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The orthosteric binding pocket


More entries for 6YZ4
6YZ4Alternative model: AChain: A


Structural information
DFG conformation:out-like
αC-helix conformation:in
G-rich loop angle (distance):-
G-rich loop rotation:-
Quality Score:6.4
Resolution:1.7 Å
Missing Residues:4
Missing Atoms:0
Ligand binding mode
Waters
Cluster
I2
I3
Ligand
No
No
Protein
Yes
No

Allosteric Ligand
Allosteric ligand:1E8
2D structure of the allostericligand
Pocket alignment
Uniprot sequence:GEMGSGTCGQVWKIAVKQMRILMDLDVVLKSHPYIVQCFGTFIAMELMGTCAEKLKKRMLKEKHGVIHRDVKPSNILLLCDFGIS
Sequence structure:GEMG____GQVWKIAVKQMRILMDLDVVLKSHPYIVQCFGTFIAMELMGTCAEKLKKRMLKEKHGVIHRDVKPSNILLLCDFGIS