Version: 3.2
Updated: 24-Dec-2025
Doublecortin like kinase 1
Kinase structure
Kinase:DCLK1
Family:DCAMKL
Group:CAMK
Species:HUMAN
IUPHAR/BPS ID:2005
PDB:6KYR
sc-PDB:
KIDFamMap:Search
Release date:2020-09-22
Chain:A
(Alternate) Model:A
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The orthosteric binding pocket


More entries for 6KYR
6KYRAlternative model: AChain: B
6KYRAlternative model: BChain: A
6KYRAlternative model: BChain: B


Structural information
DFG conformation:in
αC-helix conformation:in
G-rich loop angle (distance):73.4° (20.3Å)
G-rich loop rotation:30.6°
Quality Score:8
Resolution:2.206 Å
Missing Residues:0
Missing Atoms:0
Ligand binding mode
Waters
Cluster
I2
I4
I5
I8
Ligand
No
No
No
No
Protein
No
Yes
Yes
Yes

Pocket alignment
Uniprot sequence:RTIGDGNFAVVKEYALKIIMIQNEVSILRRVKPNIVLLIEEYLVMELVKGGDLFDAITSYLHSLNIVHRDIKPENLLVLGDFGLA
Sequence structure:RTIGDGNFAVVKEYALKIIMIQNEVSILRRVKPNIVLLIEEYLVMELVKGGDLFDAITSYLHSLNIVHRDIKPENLLVLGDFGLA