Version: 3.2
Updated: 29-Oct-2025
Mitogen-activated protein kinase-activated protein kinase 2
Kinase structure
Kinase:MAPKAPK2
Family:MAPKAPK
Group:CAMK
Species:HUMAN
IUPHAR/BPS ID:2094
PDB:2ONL
sc-PDB:
KIDFamMap:Search
Release date:2007-02-06
PubMed: 17255097
Chain:C
Click to open a 3D viewer
The orthosteric binding pocket


More entries for 2ONL
2ONLChain: A
2ONLChain: B
2ONLChain: D


Structural information
DFG conformation:in
αC-helix conformation:in
G-rich loop angle (distance):128.5° (30.9Å)
G-rich loop rotation:157.4°
Quality Score:8
Resolution:4 Å
Missing Residues:0
Missing Atoms:8

Pocket alignment
Uniprot sequence:QVLGLGINGKVLQFALKMLKARREVELHWRASPHIVRIVDVLIVMECLDGGELFSRIQDYLHSINIAHRDVKPENLLYLTDFGFA
Sequence structure:NAIIDDYKVKVLQFALKMLKARREVELHWRASPHIVRIVDVLIVMECLDGGELFSRIQDYLHSINIAHRDVKPENLLYLTDFGFA