Search results (108 entries covering 28 PDB structures)

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#	Kinase	Family	Group	PDB	Chain	(Alternate) Model	Orthosteric ligand	Organism	Details	File
	MAPKAPK2	MAPKAPK	CAMK	8xx1	A	A	-	Human	Show
	MAPKAPK2	MAPKAPK	CAMK	8xx1	A	B	-	Human	Show
	MAPKAPK2	MAPKAPK	CAMK	2jbp	L		2-(2-quinolin-3-ylpyridin-4-yl)-1,5,6,7-tetrahydro-4h-pyrrolo[3,2-c]pyridin-4-one	Human	Show
	MAPKAPK2	MAPKAPK	CAMK	3r2b	K		-	Human	Show
	MAPKAPK2	MAPKAPK	CAMK	3r2b	A		2'-[2-(1,3-benzodioxol-5-yl)pyrimidin-4-yl]-5',6'-dihydrospiro[piperidine-4,7'-pyrrolo[3,2-c]pyridin]-4'(1'h)-one	Human	Show
	MAPKAPK2	MAPKAPK	CAMK	3wi6	E		n-[(3s)-piperidin-3-yl]-7,8-dihydro-6h-pyrazolo[1,5-a]pyrrolo[3,2-e]pyrimidin-5-amine	Human	Show
	MAPKAPK2	MAPKAPK	CAMK	2onl	D		-	Human	Show
	MAPKAPK2	MAPKAPK	CAMK	3kc3	D		n~4~-[7-(1-benzofuran-2-yl)-1h-indazol-5-yl]pyrimidine-2,4-diamine	Human	Show
	MAPKAPK2	MAPKAPK	CAMK	3r2b	H		-	Human	Show
	MAPKAPK2	MAPKAPK	CAMK	3gok	C		2-(2-quinolin-3-ylpyridin-4-yl)-1,5,6,7-tetrahydro-4h-pyrrolo[3,2-c]pyridin-4-one	Human	Show
	MAPKAPK2	MAPKAPK	CAMK	3kc3	E		n~4~-[7-(1-benzofuran-2-yl)-1h-indazol-5-yl]pyrimidine-2,4-diamine	Human	Show
	MAPKAPK2	MAPKAPK	CAMK	1kwp	B		-	Human	Show
	MAPKAPK2	MAPKAPK	CAMK	3kga	A	B	6-{3-amino-1-[3-(1h-indol-6-yl)phenyl]-1h-pyrazol-4-yl}-3,4-dihydroisoquinolin-1(2h)-one	Human	Show
	MAPKAPK2	MAPKAPK	CAMK	3kc3	G		-	Human	Show
	MAPKAPK2	MAPKAPK	CAMK	3gok	K		2-(2-quinolin-3-ylpyridin-4-yl)-1,5,6,7-tetrahydro-4h-pyrrolo[3,2-c]pyridin-4-one	Human	Show
	MAPKAPK2	MAPKAPK	CAMK	6tca	A	B	-	Human	Show
	MAPKAPK2	MAPKAPK	CAMK	3a2c	C		n~7~-(4-ethoxyphenyl)-6-methyl-n~5~-[(3s)-piperidin-3-yl]pyrazolo[1,5-a]pyrimidine-5,7-diamine	Human	Show
	MAPKAPK2	MAPKAPK	CAMK	2jbp	G		2-(2-quinolin-3-ylpyridin-4-yl)-1,5,6,7-tetrahydro-4h-pyrrolo[3,2-c]pyridin-4-one	Human	Show
	MAPKAPK2	MAPKAPK	CAMK	3r30	A	A	1-(2-aminoethyl)-3-[2-(quinolin-3-yl)pyridin-4-yl]-1h-pyrazole-5-carboxylic acid	Human	Show
	MAPKAPK2	MAPKAPK	CAMK	4tyh	A	A	-	Human	Show
	MAPKAPK2	MAPKAPK	CAMK	3gok	B		2-(2-quinolin-3-ylpyridin-4-yl)-1,5,6,7-tetrahydro-4h-pyrrolo[3,2-c]pyridin-4-one	Human	Show
	MAPKAPK2	MAPKAPK	CAMK	2oza	A		-	Human	Show
	MAPKAPK2	MAPKAPK	CAMK	3a2c	E		n~7~-(4-ethoxyphenyl)-6-methyl-n~5~-[(3s)-piperidin-3-yl]pyrazolo[1,5-a]pyrimidine-5,7-diamine	Human	Show
	MAPKAPK2	MAPKAPK	CAMK	1nxk	A		staurosporine	Human	Show
	MAPKAPK2	MAPKAPK	CAMK	2pzy	B		(4r)-n-[4-({[2-(dimethylamino)ethyl]amino}carbonyl)-1,3-thiazol-2-yl]-4-methyl-1-oxo-2,3,4,9-tetrahydro-1h-beta-carboline-6-carboxamide	Human	Show
	MAPKAPK2	MAPKAPK	CAMK	3r2b	G		-	Human	Show
	MAPKAPK2	MAPKAPK	CAMK	3r2b	C		-	Human	Show
	MAPKAPK2	MAPKAPK	CAMK	3a2c	F		n~7~-(4-ethoxyphenyl)-6-methyl-n~5~-[(3s)-piperidin-3-yl]pyrazolo[1,5-a]pyrimidine-5,7-diamine	Human	Show
	MAPKAPK2	MAPKAPK	CAMK	3kc3	B		n~4~-[7-(1-benzofuran-2-yl)-1h-indazol-5-yl]pyrimidine-2,4-diamine	Human	Show
	MAPKAPK2	MAPKAPK	CAMK	2jbp	F		2-(2-quinolin-3-ylpyridin-4-yl)-1,5,6,7-tetrahydro-4h-pyrrolo[3,2-c]pyridin-4-one	Human	Show
	MAPKAPK2	MAPKAPK	CAMK	3kc3	C		n~4~-[7-(1-benzofuran-2-yl)-1h-indazol-5-yl]pyrimidine-2,4-diamine	Human	Show
	MAPKAPK2	MAPKAPK	CAMK	3fpm	A		3-{[(1r)-1-phenylethyl]amino}-4-(pyridin-4-ylamino)cyclobut-3-ene-1,2-dione	Human	Show
	MAPKAPK2	MAPKAPK	CAMK	2jbp	E		2-(2-quinolin-3-ylpyridin-4-yl)-1,5,6,7-tetrahydro-4h-pyrrolo[3,2-c]pyridin-4-one	Human	Show
	MAPKAPK2	MAPKAPK	CAMK	3r2b	E		-	Human	Show
	MAPKAPK2	MAPKAPK	CAMK	3a2c	B		n~7~-(4-ethoxyphenyl)-6-methyl-n~5~-[(3s)-piperidin-3-yl]pyrazolo[1,5-a]pyrimidine-5,7-diamine	Human	Show
	MAPKAPK2	MAPKAPK	CAMK	2jbp	B		2-(2-quinolin-3-ylpyridin-4-yl)-1,5,6,7-tetrahydro-4h-pyrrolo[3,2-c]pyridin-4-one	Human	Show
	MAPKAPK2	MAPKAPK	CAMK	3gok	F		2-(2-quinolin-3-ylpyridin-4-yl)-1,5,6,7-tetrahydro-4h-pyrrolo[3,2-c]pyridin-4-one	Human	Show
	MAPKAPK2	MAPKAPK	CAMK	2pzy	A		(4r)-n-[4-({[2-(dimethylamino)ethyl]amino}carbonyl)-1,3-thiazol-2-yl]-4-methyl-1-oxo-2,3,4,9-tetrahydro-1h-beta-carboline-6-carboxamide	Human	Show
	MAPKAPK2	MAPKAPK	CAMK	2jbp	H		2-(2-quinolin-3-ylpyridin-4-yl)-1,5,6,7-tetrahydro-4h-pyrrolo[3,2-c]pyridin-4-one	Human	Show
	MAPKAPK2	MAPKAPK	CAMK	3r2b	D		-	Human	Show
	MAPKAPK2	MAPKAPK	CAMK	6t8x	A		(10r)-10-methyl-3-(6-methylpyridin-3-yl)-9,10,11,12-tetrahydro-8h-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one	Human	Show
	MAPKAPK2	MAPKAPK	CAMK	3kc3	A		n~4~-[7-(1-benzofuran-2-yl)-1h-indazol-5-yl]pyrimidine-2,4-diamine	Human	Show
	MAPKAPK2	MAPKAPK	CAMK	1nxk	D		staurosporine	Human	Show
	MAPKAPK2	MAPKAPK	CAMK	2onl	C		-	Human	Show
	MAPKAPK2	MAPKAPK	CAMK	3gok	H		2-(2-quinolin-3-ylpyridin-4-yl)-1,5,6,7-tetrahydro-4h-pyrrolo[3,2-c]pyridin-4-one	Human	Show
	MAPKAPK2	MAPKAPK	CAMK	3kc3	H		n~4~-[7-(1-benzofuran-2-yl)-1h-indazol-5-yl]pyrimidine-2,4-diamine	Human	Show
	MAPKAPK2	MAPKAPK	CAMK	3gok	I		2-(2-quinolin-3-ylpyridin-4-yl)-1,5,6,7-tetrahydro-4h-pyrrolo[3,2-c]pyridin-4-one	Human	Show
	MAPKAPK2	MAPKAPK	CAMK	3a2c	A		n~7~-(4-ethoxyphenyl)-6-methyl-n~5~-[(3s)-piperidin-3-yl]pyrazolo[1,5-a]pyrimidine-5,7-diamine	Human	Show
	MAPKAPK2	MAPKAPK	CAMK	3wi6	A		n-[(3s)-piperidin-3-yl]-7,8-dihydro-6h-pyrazolo[1,5-a]pyrrolo[3,2-e]pyrimidin-5-amine	Human	Show
	MAPKAPK2	MAPKAPK	CAMK	3gok	L		2-(2-quinolin-3-ylpyridin-4-yl)-1,5,6,7-tetrahydro-4h-pyrrolo[3,2-c]pyridin-4-one	Human	Show
	MAPKAPK2	MAPKAPK	CAMK	1nxk	C		staurosporine	Human	Show
	MAPKAPK2	MAPKAPK	CAMK	3m2w	A	A	2'-(2-fluorophenyl)-1-methyl-6',8',9',11'-tetrahydrospiro[azetidine-3,10'-pyrido[3',4':4,5]pyrrolo[2,3-f]isoquinolin]-7'(5'h)-one	Human	Show
	MAPKAPK2	MAPKAPK	CAMK	6tca	G	B	-	Human	Show
	MAPKAPK2	MAPKAPK	CAMK	3fyk	X		(3r)-3-(aminomethyl)-9-methoxy-1,2,3,4-tetrahydro-5h-[1]benzothieno[3,2-e][1,4]diazepin-5-one	Human	Show
	MAPKAPK2	MAPKAPK	CAMK	3a2c	H		n~7~-(4-ethoxyphenyl)-6-methyl-n~5~-[(3s)-piperidin-3-yl]pyrazolo[1,5-a]pyrimidine-5,7-diamine	Human	Show
	MAPKAPK2	MAPKAPK	CAMK	6tca	A	A	-	Human	Show
	MAPKAPK2	MAPKAPK	CAMK	3a2c	L		n~7~-(4-ethoxyphenyl)-6-methyl-n~5~-[(3s)-piperidin-3-yl]pyrazolo[1,5-a]pyrimidine-5,7-diamine	Human	Show
	MAPKAPK2	MAPKAPK	CAMK	6tca	E	B	-	Human	Show
	MAPKAPK2	MAPKAPK	CAMK	6tca	C	A	-	Human	Show
	MAPKAPK2	MAPKAPK	CAMK	3r30	A	B	1-(2-aminoethyl)-3-[2-(quinolin-3-yl)pyridin-4-yl]-1h-pyrazole-5-carboxylic acid	Human	Show
	MAPKAPK2	MAPKAPK	CAMK	3gok	A		2-(2-quinolin-3-ylpyridin-4-yl)-1,5,6,7-tetrahydro-4h-pyrrolo[3,2-c]pyridin-4-one	Human	Show
	MAPKAPK2	MAPKAPK	CAMK	3gok	D		2-(2-quinolin-3-ylpyridin-4-yl)-1,5,6,7-tetrahydro-4h-pyrrolo[3,2-c]pyridin-4-one	Human	Show
	MAPKAPK2	MAPKAPK	CAMK	6tca	G	A	-	Human	Show
	MAPKAPK2	MAPKAPK	CAMK	3a2c	K		n~7~-(4-ethoxyphenyl)-6-methyl-n~5~-[(3s)-piperidin-3-yl]pyrazolo[1,5-a]pyrimidine-5,7-diamine	Human	Show
	MAPKAPK2	MAPKAPK	CAMK	3gok	G		2-(2-quinolin-3-ylpyridin-4-yl)-1,5,6,7-tetrahydro-4h-pyrrolo[3,2-c]pyridin-4-one	Human	Show
	MAPKAPK2	MAPKAPK	CAMK	2jbp	A		2-(2-quinolin-3-ylpyridin-4-yl)-1,5,6,7-tetrahydro-4h-pyrrolo[3,2-c]pyridin-4-one	Human	Show
	MAPKAPK2	MAPKAPK	CAMK	2jbp	I		2-(2-quinolin-3-ylpyridin-4-yl)-1,5,6,7-tetrahydro-4h-pyrrolo[3,2-c]pyridin-4-one	Human	Show
	MAPKAPK2	MAPKAPK	CAMK	3fyj	X		(10r)-10-methyl-3-(6-methylpyridin-3-yl)-9,10,11,12-tetrahydro-8h-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one	Human	Show
	MAPKAPK2	MAPKAPK	CAMK	3wi6	F		n-[(3s)-piperidin-3-yl]-7,8-dihydro-6h-pyrazolo[1,5-a]pyrrolo[3,2-e]pyrimidin-5-amine	Human	Show
	MAPKAPK2	MAPKAPK	CAMK	2jbp	C		2-(2-quinolin-3-ylpyridin-4-yl)-1,5,6,7-tetrahydro-4h-pyrrolo[3,2-c]pyridin-4-one	Human	Show
	MAPKAPK2	MAPKAPK	CAMK	2jbp	D		2-(2-quinolin-3-ylpyridin-4-yl)-1,5,6,7-tetrahydro-4h-pyrrolo[3,2-c]pyridin-4-one	Human	Show
	MAPKAPK2	MAPKAPK	CAMK	3r2b	L		-	Human	Show
	MAPKAPK2	MAPKAPK	CAMK	2pzy	D		-	Human	Show
	MAPKAPK2	MAPKAPK	CAMK	3r2b	B		2'-[2-(1,3-benzodioxol-5-yl)pyrimidin-4-yl]-5',6'-dihydrospiro[piperidine-4,7'-pyrrolo[3,2-c]pyridin]-4'(1'h)-one	Human	Show
	MAPKAPK2	MAPKAPK	CAMK	3r2y	A		2-(2-quinolin-3-ylpyridin-4-yl)-1,5,6,7-tetrahydro-4h-pyrrolo[3,2-c]pyridin-4-one	Human	Show
	MAPKAPK2	MAPKAPK	CAMK	3m42	A		2-[5-(2-methoxyethoxy)pyridin-3-yl]-8,9,10,11-tetrahydro-7h-pyrido[3',4':4,5]pyrrolo[2,3-f]isoquinolin-7-one	Human	Show
	MAPKAPK2	MAPKAPK	CAMK	3a2c	I		n~7~-(4-ethoxyphenyl)-6-methyl-n~5~-[(3s)-piperidin-3-yl]pyrazolo[1,5-a]pyrimidine-5,7-diamine	Human	Show
	MAPKAPK2	MAPKAPK	CAMK	6tca	C	B	-	Human	Show
	MAPKAPK2	MAPKAPK	CAMK	3r2b	F		-	Human	Show
	MAPKAPK2	MAPKAPK	CAMK	3wi6	C		n-[(3s)-piperidin-3-yl]-7,8-dihydro-6h-pyrazolo[1,5-a]pyrrolo[3,2-e]pyrimidin-5-amine	Human	Show
	MAPKAPK2	MAPKAPK	CAMK	2pzy	C		staurosporine	Human	Show
	MAPKAPK2	MAPKAPK	CAMK	3kc3	F		n~4~-[7-(1-benzofuran-2-yl)-1h-indazol-5-yl]pyrimidine-2,4-diamine	Human	Show
	MAPKAPK2	MAPKAPK	CAMK	3a2c	J		n~7~-(4-ethoxyphenyl)-6-methyl-n~5~-[(3s)-piperidin-3-yl]pyrazolo[1,5-a]pyrimidine-5,7-diamine	Human	Show
	MAPKAPK2	MAPKAPK	CAMK	1nxk	B		staurosporine	Human	Show
	MAPKAPK2	MAPKAPK	CAMK	3r2b	I		-	Human	Show
	MAPKAPK2	MAPKAPK	CAMK	1ny3	A		adenosine-5'-diphosphate	Human	Show
	MAPKAPK2	MAPKAPK	CAMK	1kwp	A		-	Human	Show
	MAPKAPK2	MAPKAPK	CAMK	3ka0	A		6-{5-[(2-aminopyrimidin-4-yl)amino]-2-hydroxyphenyl}-n-methylidene-1-benzothiophene-2-carboxamide	Human	Show
	MAPKAPK2	MAPKAPK	CAMK	2p3g	X		2-[2-(2-fluorophenyl)pyridin-4-yl]-1,5,6,7-tetrahydro-4h-pyrrolo[3,2-c]pyridin-4-one	Human	Show
	MAPKAPK2	MAPKAPK	CAMK	8xu4	A		-	Human	Show
	MAPKAPK2	MAPKAPK	CAMK	3wi6	D		n-[(3s)-piperidin-3-yl]-7,8-dihydro-6h-pyrazolo[1,5-a]pyrrolo[3,2-e]pyrimidin-5-amine	Human	Show
	MAPKAPK2	MAPKAPK	CAMK	3gok	J		2-(2-quinolin-3-ylpyridin-4-yl)-1,5,6,7-tetrahydro-4h-pyrrolo[3,2-c]pyridin-4-one	Human	Show
	MAPKAPK2	MAPKAPK	CAMK	3kc3	I		n~4~-[7-(1-benzofuran-2-yl)-1h-indazol-5-yl]pyrimidine-2,4-diamine	Human	Show
	MAPKAPK2	MAPKAPK	CAMK	6tca	E	A	-	Human	Show
	MAPKAPK2	MAPKAPK	CAMK	3kga	A	A	6-{3-amino-1-[3-(1h-indol-6-yl)phenyl]-1h-pyrazol-4-yl}-3,4-dihydroisoquinolin-1(2h)-one	Human	Show
	MAPKAPK2	MAPKAPK	CAMK	2jbo	A		2-(2-quinolin-3-ylpyridin-4-yl)-1,5,6,7-tetrahydro-4h-pyrrolo[3,2-c]pyridin-4-one	Human	Show
	MAPKAPK2	MAPKAPK	CAMK	3kc3	L		n~4~-[7-(1-benzofuran-2-yl)-1h-indazol-5-yl]pyrimidine-2,4-diamine	Human	Show
	MAPKAPK2	MAPKAPK	CAMK	3a2c	G		n~7~-(4-ethoxyphenyl)-6-methyl-n~5~-[(3s)-piperidin-3-yl]pyrazolo[1,5-a]pyrimidine-5,7-diamine	Human	Show
	MAPKAPK2	MAPKAPK	CAMK	3r2b	J		-	Human	Show
	MAPKAPK2	MAPKAPK	CAMK	3wi6	B		n-[(3s)-piperidin-3-yl]-7,8-dihydro-6h-pyrazolo[1,5-a]pyrrolo[3,2-e]pyrimidin-5-amine	Human	Show
	MAPKAPK2	MAPKAPK	CAMK	2jbp	K		2-(2-quinolin-3-ylpyridin-4-yl)-1,5,6,7-tetrahydro-4h-pyrrolo[3,2-c]pyridin-4-one	Human	Show
	MAPKAPK2	MAPKAPK	CAMK	3m2w	A	B	2'-(2-fluorophenyl)-1-methyl-6',8',9',11'-tetrahydrospiro[azetidine-3,10'-pyrido[3',4':4,5]pyrrolo[2,3-f]isoquinolin]-7'(5'h)-one	Human	Show
	MAPKAPK2	MAPKAPK	CAMK	4tyh	A	B	-	Human	Show
	MAPKAPK2	MAPKAPK	CAMK	3gok	E		2-(2-quinolin-3-ylpyridin-4-yl)-1,5,6,7-tetrahydro-4h-pyrrolo[3,2-c]pyridin-4-one	Human	Show
	MAPKAPK2	MAPKAPK	CAMK	3a2c	D		n~7~-(4-ethoxyphenyl)-6-methyl-n~5~-[(3s)-piperidin-3-yl]pyrazolo[1,5-a]pyrimidine-5,7-diamine	Human	Show
	MAPKAPK2	MAPKAPK	CAMK	3kc3	K		n~4~-[7-(1-benzofuran-2-yl)-1h-indazol-5-yl]pyrimidine-2,4-diamine	Human	Show
	MAPKAPK2	MAPKAPK	CAMK	3kc3	J		n~4~-[7-(1-benzofuran-2-yl)-1h-indazol-5-yl]pyrimidine-2,4-diamine	Human	Show
	MAPKAPK2	MAPKAPK	CAMK	2jbp	J		-	Human	Show

Division of Medicinal Chemistry - Vrije Universiteit Amsterdam