Version: 3.2
Updated: 29-Oct-2025
Mitogen-activated protein kinase-activated protein kinase 2
Kinase structure
Kinase:MAPKAPK2
Family:MAPKAPK
Group:CAMK
Species:HUMAN
IUPHAR/BPS ID:2094
PDB:3R2B
sc-PDB:
KIDFamMap:Search
Release date:2011-05-25
PubMed: 21565500
Chain:H
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The orthosteric binding pocket


More entries for 3R2B
3R2BChain: A
3R2BChain: B
3R2BChain: C
3R2BChain: D
3R2BChain: E
3R2BChain: F
3R2BChain: G
3R2BChain: I
3R2BChain: J
3R2BChain: K
3R2BChain: L


Structural information
DFG conformation:in
αC-helix conformation:in
G-rich loop angle (distance):47.7° (14.6Å)
G-rich loop rotation:74.6°
Quality Score:8
Resolution:2.9 Å
Missing Residues:0
Missing Atoms:21

Pocket alignment
Uniprot sequence:QVLGLGINGKVLQFALKMLKARREVELHWRASPHIVRIVDVLIVMECLDGGELFSRIQDYLHSINIAHRDVKPENLLYLTDFGFA
Sequence structure:QVLGLGINGKVLQFALKMLKARREVELHWRASPHIVRIVDVLIVMECLDGGELFSRIQDYLHSINIAHRDVKPENLLYLTDFGFA