Version: 3.2
Updated: 29-Oct-2025
Mitogen-activated protein kinase-activated protein kinase 2
Kinase structure
Kinase:MAPKAPK2
Family:MAPKAPK
Group:CAMK
Species:HUMAN
IUPHAR/BPS ID:2094
PDB:3KC3
sc-PDB:
KIDFamMap:Search
Release date:2010-01-12
PubMed: 19919896
Chain:G
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The orthosteric binding pocket


More entries for 3KC3
3KC3Chain: A
3KC3Chain: B
3KC3Chain: C
3KC3Chain: D
3KC3Chain: E
3KC3Chain: F
3KC3Chain: H
3KC3Chain: I
3KC3Chain: J
3KC3Chain: K
3KC3Chain: L


Structural information
DFG conformation:in
αC-helix conformation:in
G-rich loop angle (distance):45.9° (14Å)
G-rich loop rotation:51.7°
Quality Score:8
Resolution:2.9 Å
Missing Residues:0
Missing Atoms:0

Pocket alignment
Uniprot sequence:QVLGLGINGKVLQFALKMLKARREVELHWRASPHIVRIVDVLIVMECLDGGELFSRIQDYLHSINIAHRDVKPENLLYLTDFGFA
Sequence structure:QVLGLGINGKVLQFALKMLKARREVELHWRASPHIVRIVDVLIVMECLDGGELFSRIQDYLHSINIAHRDVKPENLLYLTDFGFA