Version: 3.2
Updated: 29-Oct-2025
Mitogen-activated protein kinase-activated protein kinase 2
Kinase structure
Kinase:MAPKAPK2
Family:MAPKAPK
Group:CAMK
Species:HUMAN
IUPHAR/BPS ID:2094
PDB:2JBP
sc-PDB:
KIDFamMap:Search
Release date:2007-03-20
PubMed: 17132859
Chain:J
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The orthosteric binding pocket


More entries for 2JBP
2JBPChain: A
2JBPChain: B
2JBPChain: C
2JBPChain: D
2JBPChain: E
2JBPChain: F
2JBPChain: G
2JBPChain: H
2JBPChain: I
2JBPChain: K
2JBPChain: L


Structural information
DFG conformation:in
αC-helix conformation:in
G-rich loop angle (distance):50.9° (15.2Å)
G-rich loop rotation:69.7°
Quality Score:8
Resolution:3.31 Å
Missing Residues:0
Missing Atoms:0

Pocket alignment
Uniprot sequence:QVLGLGINGKVLQFALKMLKARREVELHWRASPHIVRIVDVLIVMECLDGGELFSRIQDYLHSINIAHRDVKPENLLYLTDFGFA
Sequence structure:QVLGLGINGKVLQFALKMLKARREVELHWRASPHIVRIVDVLIVMECLDGGELFSRIQDYLHSINIAHRDVKPENLLYLTDFGFA