PDB-code
| Kinase structure | |
| Kinase: | ACVR1 (ALK2) |
| Family: | STKR |
| Group: | TKL |
| Species: | HUMAN |
| IUPHAR/BPS ID: | 1785 |
| PDB: | 5S7M |
| sc-PDB: | |
| KIDFamMap: | Search |
| Release date: | 2021-06-23 |
| Chain: | A |
| (Alternate) Model: | C |
| More entries for 5S7M | |||||
| 5S7M | Alternative model: | A | Chain: | A | |
| 5S7M | Alternative model: | B | Chain: | A | |
| Structural information | |
| DFG conformation: | in |
| αC-helix conformation: | in |
| G-rich loop angle (distance): | 55.6° (17.1Å) |
| G-rich loop rotation: | 42.6° |
| Quality Score: | 6.8 |
| Resolution: | 1.32 Å |
| Missing Residues: | 3 |
| Missing Atoms: | 25 |
| Ligand binding mode | ||||
| Waters | ||||
| Cluster I2 I5 I10 | Ligand No No No | Protein No Yes Yes | ||
| Allosteric Ligand | |
| Allosteric ligand: | LU8 |
 | |
| Pocket alignment | |
| Uniprot sequence: | ECVGKGRYGEVWRVAVKIFSWFRETELYNTVMENILGFIASWLITHYHEMGSLYDYLQLTQGKPAIAHRDLKSKNILVIADLGLA |
| Sequence structure: | ECVGKGRYGEVWRVAVKIFSWFRETELYNTVMEN_LGFIAS_LITHYHEMGSLY_YLQLTQGKPAIAHRDLKSKNILVIADLGLA |
