PDB-code
Search results (202 entries covering 77 PDB structures)
| # | Kinase | Family | Group | PDB | Chain | (Alternate) Model | Orthosteric ligand | Organism | Details | File |
|---|---|---|---|---|---|---|---|---|---|---|
 | ACVR1 (ALK2) | STKR | TKL | 8c7z | A | A | 9-piperazin-1-yl-4-(3,4,5-trimethoxyphenyl)-5,6-dihydro-[1]benzoxepino[5,4-c]pyridine | Human | Show |  |
| ACVR1 (ALK2) | STKR | TKL | 6acr | B | n-(4-methoxyphenyl)-4-[3-(pyridin-3-yl)-1h-pyrazol-4-yl]pyrimidin-2-amine | Human | Show | | |
| ACVR1 (ALK2) | STKR | TKL | 5s7m | A | A | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 5s7d | A | B | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 5s7q | A | A | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 6t8n | A | B | cyclopropyl-[4-[6-[5-(4-ethoxy-1-propan-2-yl-piperidin-4-yl)pyridin-2-yl]pyrrolo[1,2-b]pyridazin-4-yl]piperazin-1-yl]methanone | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 5s7r | A | A | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 6t8n | B | A | cyclopropyl-[4-[6-[5-(4-ethoxy-1-propan-2-yl-piperidin-4-yl)pyridin-2-yl]pyrrolo[1,2-b]pyridazin-4-yl]piperazin-1-yl]methanone | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 8r7g | A | B | 2-fluoranyl-6-methoxy-4-[4-methyl-5-[4-(4-propan-2-ylpiperazin-1-yl)phenyl]pyridin-3-yl]benzamide | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 5s7i | A | A | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 5s7c | A | C | - | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 5s79 | A | B | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 5s7t | A | B | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 5s7c | A | B | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 7a21 | A | B | 4-methyl-3-[4-(pyrrolidin-1-ylmethyl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 5s7b | A | A | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 5s88 | A | A | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 5s7e | A | B | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 3mtf | B | B | 3-[6-amino-5-(3,4,5-trimethoxyphenyl)pyridin-3-yl]phenol | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 5s7a | A | B | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 6t8n | A | A | cyclopropyl-[4-[6-[5-(4-ethoxy-1-propan-2-yl-piperidin-4-yl)pyridin-2-yl]pyrrolo[1,2-b]pyridazin-4-yl]piperazin-1-yl]methanone | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 5s9k | A | A | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 7a21 | B | A | 4-methyl-3-[4-(pyrrolidin-1-ylmethyl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 6zgc | A | n-(5-chloro-1,3-benzodioxol-4-yl)-7-[2-(4-methylpiperazin-1-yl)ethoxy]-5-(tetrahydro-2h-pyran-4-yloxy)quinazolin-4-amine | Human | Show | | |
| ACVR1 (ALK2) | STKR | TKL | 5s7x | A | A | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 3q4u | B | A | 4-[6-(4-piperazin-1-ylphenyl)pyrazolo[1,5-a]pyrimidin-3-yl]quinoline | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 5s7o | A | C | - | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 5s7j | A | B | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 7c3g | A | B | ~{n}-[4-(4-methylpiperazin-1-yl)phenyl]-4-(2-pyridin-3-yl-6,7-dihydro-4~{h}-pyrazolo[5,1-c][1,4]oxazin-3-yl)pyrimidin-2-amine | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 6srh | A | B | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 5s7k | A | A | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 3q4u | C | B | 4-[6-(4-piperazin-1-ylphenyl)pyrazolo[1,5-a]pyrimidin-3-yl]quinoline | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 4bgg | A | B | 1-{4-[5-(3,4,5-trimethoxyphenyl)pyridin-3-yl]phenyl}piperazine | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 4bgg | B | A | 1-{4-[5-(3,4,5-trimethoxyphenyl)pyridin-3-yl]phenyl}piperazine | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 6zgc | D | n-(5-chloro-1,3-benzodioxol-4-yl)-7-[2-(4-methylpiperazin-1-yl)ethoxy]-5-(tetrahydro-2h-pyran-4-yloxy)quinazolin-4-amine | Human | Show | | |
| ACVR1 (ALK2) | STKR | TKL | 5s7s | A | C | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 3q4u | A | A | 4-[6-(4-piperazin-1-ylphenyl)pyrazolo[1,5-a]pyrimidin-3-yl]quinoline | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 5s7i | A | C | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 5s7r | A | B | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 6uns | A | B | 4-[6-(4-piperazin-1-ylphenyl)pyrazolo[1,5-a]pyrimidin-3-yl]quinoline | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 5s7n | A | A | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 6jux | A | B | 4-(1-ethyl-3-pyridin-3-yl-pyrazol-4-yl)-~{n}-(4-piperazin-1-ylphenyl)pyrimidin-2-amine | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 3h9r | A | 6-[4-(2-piperidin-1-ylethoxy)phenyl]-3-pyridin-4-ylpyrazolo[1,5-a]pyrimidine | Human | Show | | |
| ACVR1 (ALK2) | STKR | TKL | 6uns | A | A | 4-[6-(4-piperazin-1-ylphenyl)pyrazolo[1,5-a]pyrimidin-3-yl]quinoline | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 5oy6 | D | cyclical inhibitor od36 | Human | Show | | |
| ACVR1 (ALK2) | STKR | TKL | 5oxg | C | A | 5-[6-(4-piperazin-1-ylphenyl)pyrazolo[1,5-a]pyrimidin-3-yl]quinoline | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 5oxg | C | B | 5-[6-(4-piperazin-1-ylphenyl)pyrazolo[1,5-a]pyrimidin-3-yl]quinoline | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 7a21 | A | A | 4-methyl-3-[4-(pyrrolidin-1-ylmethyl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 5s84 | A | B | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 6tn8 | A | A | 4-[4-[(dimethylamino)methyl]-2,5-dimethoxy-phenyl]-2-methyl-2,7-naphthyridin-1-one | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 6zgc | C | n-(5-chloro-1,3-benzodioxol-4-yl)-7-[2-(4-methylpiperazin-1-yl)ethoxy]-5-(tetrahydro-2h-pyran-4-yloxy)quinazolin-4-amine | Human | Show | | |
| ACVR1 (ALK2) | STKR | TKL | 6i1s | A | B | (4~{s},5~{r},6~{z},9~{s},10~{s},12~{e})-16-(ethylamino)-4,5-dimethyl-9,10,18-tris(oxidanyl)-3-oxabicyclo[12.4.0]octadeca-1(14),6,12,15,17-pentaene-2,8-dione | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 6gin | B | B | 3-(4-morpholin-4-ylphenyl)-6-quinolin-4-yl-quinazolin-4-one | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 5s9k | A | B | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 5s7n | A | B | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 3q4u | D | B | 4-[6-(4-piperazin-1-ylphenyl)pyrazolo[1,5-a]pyrimidin-3-yl]quinoline | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 5s7h | A | B | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 5s81 | A | A | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 5s7w | A | B | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 5s7i | A | B | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 5s7o | A | B | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 6srh | A | A | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 6szm | A | A | 1-[4-[4-methyl-5-(3,4,5-trimethoxyphenyl)pyridin-3-yl]phenyl]piperazine | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 3mtf | A | B | 3-[6-amino-5-(3,4,5-trimethoxyphenyl)pyridin-3-yl]phenol | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 5s7l | A | C | - | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 3q4u | B | B | 4-[6-(4-piperazin-1-ylphenyl)pyrazolo[1,5-a]pyrimidin-3-yl]quinoline | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 5s7s | A | A | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 6z36 | B | B | 4-methyl-3-(4-piperidin-4-ylphenyl)-5-(3,4,5-trimethoxyphenyl)pyridine | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 5oxg | D | A | 5-[6-(4-piperazin-1-ylphenyl)pyrazolo[1,5-a]pyrimidin-3-yl]quinoline | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 5s80 | A | B | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 8c7w | A | A | 6-methyl-9-piperazin-1-yl-4-(3,4,5-trimethoxyphenyl)-5,7-dihydropyrido[4,3-d][2]benzazepine | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 5oy6 | A | cyclical inhibitor od36 | Human | Show | | |
| ACVR1 (ALK2) | STKR | TKL | 5s7f | A | A | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 8c7w | A | B | 6-methyl-9-piperazin-1-yl-4-(3,4,5-trimethoxyphenyl)-5,7-dihydropyrido[4,3-d][2]benzazepine | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 6zgc | B | n-(5-chloro-1,3-benzodioxol-4-yl)-7-[2-(4-methylpiperazin-1-yl)ethoxy]-5-(tetrahydro-2h-pyran-4-yloxy)quinazolin-4-amine | Human | Show | | |
| ACVR1 (ALK2) | STKR | TKL | 5s76 | A | B | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 5s89 | A | A | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 5s7z | A | B | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 5s7u | A | A | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 4c02 | A | B | 6-[4-(2-piperidin-1-ylethoxy)phenyl]-3-pyridin-4-ylpyrazolo[1,5-a]pyrimidine | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 5s7l | A | A | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 8c7z | A | B | 9-piperazin-1-yl-4-(3,4,5-trimethoxyphenyl)-5,6-dihydro-[1]benzoxepino[5,4-c]pyridine | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 5s7s | A | B | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 6t8n | B | B | cyclopropyl-[4-[6-[5-(4-ethoxy-1-propan-2-yl-piperidin-4-yl)pyridin-2-yl]pyrrolo[1,2-b]pyridazin-4-yl]piperazin-1-yl]methanone | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 6gin | B | A | 3-(4-morpholin-4-ylphenyl)-6-quinolin-4-yl-quinazolin-4-one | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 6eix | A | A | 3-[6-amino-5-(3,4,5-trimethoxyphenyl)pyridin-3-yl]phenol | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 5s7q | A | B | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 6tn8 | A | B | 4-[4-[(dimethylamino)methyl]-2,5-dimethoxy-phenyl]-2-methyl-2,7-naphthyridin-1-one | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 5s85 | A | C | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 7a21 | B | B | 4-methyl-3-[4-(pyrrolidin-1-ylmethyl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 5s7c | A | D | - | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 5s7h | A | A | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 5s7a | A | A | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 5s7y | A | B | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 3mtf | B | A | 3-[6-amino-5-(3,4,5-trimethoxyphenyl)pyridin-3-yl]phenol | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 4c02 | A | A | 6-[4-(2-piperidin-1-ylethoxy)phenyl]-3-pyridin-4-ylpyrazolo[1,5-a]pyrimidine | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 5s83 | A | B | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 5s78 | A | B | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 7nns | B | B | momelotinib | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 5s7p | A | B | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 6szm | B | A | 1-[4-[4-methyl-5-(3,4,5-trimethoxyphenyl)pyridin-3-yl]phenyl]piperazine | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 5s89 | A | B | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 5s7c | A | A | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 6gip | A | A | 2,5-dimethyl-6-quinolin-4-yl-3~{h}-quinazolin-4-one | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 4dym | A | 1-(3-{6-[(cyclopropylmethyl)amino]imidazo[1,2-b]pyridazin-3-yl}phenyl)ethanone | Human | Show | | |
| ACVR1 (ALK2) | STKR | TKL | 6t6d | A | A | 2-methoxy-4-[4-methyl-5-(4-piperazin-1-ylphenyl)pyridin-3-yl]benzamide | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 5s76 | A | A | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 6t6d | D | A | 2-methoxy-4-[4-methyl-5-(4-piperazin-1-ylphenyl)pyridin-3-yl]benzamide | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 6gin | A | B | 3-(4-morpholin-4-ylphenyl)-6-quinolin-4-yl-quinazolin-4-one | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 6gip | A | B | 2,5-dimethyl-6-quinolin-4-yl-3~{h}-quinazolin-4-one | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 5s7x | A | B | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 5s8a | A | B | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 6t6d | D | B | 2-methoxy-4-[4-methyl-5-(4-piperazin-1-ylphenyl)pyridin-3-yl]benzamide | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 4bgg | C | B | 1-{4-[5-(3,4,5-trimethoxyphenyl)pyridin-3-yl]phenyl}piperazine | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 6i1s | A | A | (4~{s},5~{r},6~{z},9~{s},10~{s},12~{e})-16-(ethylamino)-4,5-dimethyl-9,10,18-tris(oxidanyl)-3-oxabicyclo[12.4.0]octadeca-1(14),6,12,15,17-pentaene-2,8-dione | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 6z36 | B | A | 4-methyl-3-(4-piperidin-4-ylphenyl)-5-(3,4,5-trimethoxyphenyl)pyridine | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 5s77 | A | A | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 5s7p | A | A | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 5s7u | A | B | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 5s81 | A | B | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 7nns | B | A | momelotinib | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 6srh | B | A | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 5s77 | A | B | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 6eix | A | B | 3-[6-amino-5-(3,4,5-trimethoxyphenyl)pyridin-3-yl]phenol | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 5s7w | A | A | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 5s82 | A | B | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 7c3g | B | B | ~{n}-[4-(4-methylpiperazin-1-yl)phenyl]-4-(2-pyridin-3-yl-6,7-dihydro-4~{h}-pyrazolo[5,1-c][1,4]oxazin-3-yl)pyrimidin-2-amine | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 6t6d | B | B | 2-methoxy-4-[4-methyl-5-(4-piperazin-1-ylphenyl)pyridin-3-yl]benzamide | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 7c3g | B | A | ~{n}-[4-(4-methylpiperazin-1-yl)phenyl]-4-(2-pyridin-3-yl-6,7-dihydro-4~{h}-pyrazolo[5,1-c][1,4]oxazin-3-yl)pyrimidin-2-amine | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 5s88 | A | B | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 6t6d | B | A | 2-methoxy-4-[4-methyl-5-(4-piperazin-1-ylphenyl)pyridin-3-yl]benzamide | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 5s79 | A | A | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 5s7m | A | C | - | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 5s83 | A | A | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 5oxg | B | A | 5-[6-(4-piperazin-1-ylphenyl)pyrazolo[1,5-a]pyrimidin-3-yl]quinoline | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 5s7v | A | A | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 6unq | A | A | phosphoaminophosphonic acid-adenylate ester | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 5s85 | A | A | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 5oy6 | C | cyclical inhibitor od36 | Human | Show | | |
| ACVR1 (ALK2) | STKR | TKL | 8pod | A | 6-(4-piperazin-1-ylphenyl)-3-quinolin-4-yl-furo[3,2-b]pyridine | Human | Show | | |
| ACVR1 (ALK2) | STKR | TKL | 3oom | A | A | 1-{3-[6-(tetrahydro-2h-pyran-4-ylamino)imidazo[1,2-b]pyridazin-3-yl]phenyl}ethanone | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 5oxg | A | B | 5-[6-(4-piperazin-1-ylphenyl)pyrazolo[1,5-a]pyrimidin-3-yl]quinoline | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 5s7v | A | B | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 5s7j | A | A | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 5s7g | A | A | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 4bgg | D | B | 1-{4-[5-(3,4,5-trimethoxyphenyl)pyridin-3-yl]phenyl}piperazine | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 3q4u | C | A | 4-[6-(4-piperazin-1-ylphenyl)pyrazolo[1,5-a]pyrimidin-3-yl]quinoline | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 6unq | A | B | phosphoaminophosphonic acid-adenylate ester | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 6t6d | C | B | 2-methoxy-4-[4-methyl-5-(4-piperazin-1-ylphenyl)pyridin-3-yl]benzamide | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 6unr | A | phosphoaminophosphonic acid-adenylate ester | Human | Show | | |
| ACVR1 (ALK2) | STKR | TKL | 5s7e | A | A | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 5s78 | A | A | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 5s7g | A | B | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 6z36 | A | A | 4-methyl-3-(4-piperidin-4-ylphenyl)-5-(3,4,5-trimethoxyphenyl)pyridine | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 5s75 | A | B | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 5s7b | A | B | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 3mtf | A | A | 3-[6-amino-5-(3,4,5-trimethoxyphenyl)pyridin-3-yl]phenol | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 5s85 | A | B | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 5s8b | A | B | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 5s84 | A | C | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 6gi6 | A | 5-methyl-6-quinolin-5-yl-3~{h}-quinazolin-4-one | Human | Show | | |
| ACVR1 (ALK2) | STKR | TKL | 5oxg | D | B | 5-[6-(4-piperazin-1-ylphenyl)pyrazolo[1,5-a]pyrimidin-3-yl]quinoline | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 3oom | A | B | 1-{3-[6-(tetrahydro-2h-pyran-4-ylamino)imidazo[1,2-b]pyridazin-3-yl]phenyl}ethanone | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 5s7t | A | A | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 5s86 | A | A | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 3q4u | A | B | 4-[6-(4-piperazin-1-ylphenyl)pyrazolo[1,5-a]pyrimidin-3-yl]quinoline | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 5s8a | A | A | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 5oxg | A | A | 5-[6-(4-piperazin-1-ylphenyl)pyrazolo[1,5-a]pyrimidin-3-yl]quinoline | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 5s8b | A | A | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 5s7y | A | A | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 5s80 | A | A | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 3q4u | D | A | 4-[6-(4-piperazin-1-ylphenyl)pyrazolo[1,5-a]pyrimidin-3-yl]quinoline | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 6t6d | A | B | 2-methoxy-4-[4-methyl-5-(4-piperazin-1-ylphenyl)pyridin-3-yl]benzamide | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 8r7g | A | A | 2-fluoranyl-6-methoxy-4-[4-methyl-5-[4-(4-propan-2-ylpiperazin-1-yl)phenyl]pyridin-3-yl]benzamide | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 5s86 | A | B | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 5s7d | A | A | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 6szm | A | B | 1-[4-[4-methyl-5-(3,4,5-trimethoxyphenyl)pyridin-3-yl]phenyl]piperazine | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 6szm | B | B | 1-[4-[4-methyl-5-(3,4,5-trimethoxyphenyl)pyridin-3-yl]phenyl]piperazine | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 5s7k | A | B | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 5s7o | A | A | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 6srh | B | B | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 6gin | A | A | 3-(4-morpholin-4-ylphenyl)-6-quinolin-4-yl-quinazolin-4-one | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 5s7f | A | B | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 6z36 | A | B | 4-methyl-3-(4-piperidin-4-ylphenyl)-5-(3,4,5-trimethoxyphenyl)pyridine | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 5s87 | A | A | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 5s7m | A | B | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 7c3g | A | A | ~{n}-[4-(4-methylpiperazin-1-yl)phenyl]-4-(2-pyridin-3-yl-6,7-dihydro-4~{h}-pyrazolo[5,1-c][1,4]oxazin-3-yl)pyrimidin-2-amine | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 5s7z | A | A | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 5oxg | B | B | 5-[6-(4-piperazin-1-ylphenyl)pyrazolo[1,5-a]pyrimidin-3-yl]quinoline | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 4bgg | A | A | 1-{4-[5-(3,4,5-trimethoxyphenyl)pyridin-3-yl]phenyl}piperazine | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 5s82 | A | A | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 6acr | A | n-(4-methoxyphenyl)-4-[3-(pyridin-3-yl)-1h-pyrazol-4-yl]pyrimidin-2-amine | Human | Show | | |
| ACVR1 (ALK2) | STKR | TKL | 4bgg | B | B | 1-{4-[5-(3,4,5-trimethoxyphenyl)pyridin-3-yl]phenyl}piperazine | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 6t6d | C | A | 2-methoxy-4-[4-methyl-5-(4-piperazin-1-ylphenyl)pyridin-3-yl]benzamide | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 5s75 | A | A | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 4bgg | C | A | 1-{4-[5-(3,4,5-trimethoxyphenyl)pyridin-3-yl]phenyl}piperazine | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 5oy6 | B | cyclical inhibitor od36 | Human | Show | | |
| ACVR1 (ALK2) | STKR | TKL | 4bgg | D | A | 1-{4-[5-(3,4,5-trimethoxyphenyl)pyridin-3-yl]phenyl}piperazine | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 5s84 | A | A | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 6jux | A | A | 4-(1-ethyl-3-pyridin-3-yl-pyrazol-4-yl)-~{n}-(4-piperazin-1-ylphenyl)pyrimidin-2-amine | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 5s87 | A | B | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | Show | |
| ACVR1 (ALK2) | STKR | TKL | 5s7l | A | B | 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine | Human | Show | |
