Version: 3.2
Updated: 24-Dec-2025
P21 protein (Cdc42/Rac)-activated kinase 4
Kinase structure
Kinase:PAK4
Family:STE20
Group:STE
Species:HUMAN
IUPHAR/BPS ID:2136
PDB:2BVA
sc-PDB:
KIDFamMap:Search
Release date:2005-07-14
PubMed: 17292838
Chain:A
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The orthosteric binding pocket


More entries for 2BVA
2BVAChain: B


Structural information
DFG conformation:in
αC-helix conformation:in
G-rich loop angle (distance):-
G-rich loop rotation:-
Quality Score:6.1
Resolution:2.3 Å
Missing Residues:6
Missing Atoms:15
Ligand binding mode
Waters
Cluster
I6
Ligand
No
Protein
No

Pocket alignment
Uniprot sequence:IKIGEGSTGIVCIVAVKKMLLFNEVVIMRDYQENVVEMYNSWVVMEFLEGGALTDIVTHVLHAQGVIHRDIKSDSILLLSDFGFC
Sequence structure:IKIG_____IVCIVAVKKM_LFNEVVIMRDYQENVVEMYNSWVVMEFLEGGALTDIVTHVLHAQGVIHRDIKSDSILLLSDFGFC