Search results (72 entries covering 46 PDB structures)

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#	Kinase	Family	Group	PDB	Chain	(Alternate) Model	Orthosteric ligand	Organism	Details	File
	PAK4	STE20	STE	4l67	A		-	Human	Show
	PAK4	STE20	STE	4njd	A	A	n-(1h-indazol-5-yl)-n'-[2-(1h-indol-3-yl)ethyl]-6-methoxy-1,3,5-triazine-2,4-diamine	Human	Show
	PAK4	STE20	STE	4fig	A		phosphoaminophosphonic acid-adenylate ester	Human	Show
	PAK4	STE20	STE	7s48	A	A	-	Human	Show
	PAK4	STE20	STE	7s48	A	B	-	Human	Show
	PAK4	STE20	STE	8yhk	A		-	Human	Show
	PAK4	STE20	STE	4jdh	A	A	-	Human	Show
	PAK4	STE20	STE	2cdz	A	B	n2-[(1r,2s)-2-aminocyclohexyl]-n6-(3-chlorophenyl)-9-ethyl-9h-purine-2,6-diamine	Human	Show
	PAK4	STE20	STE	4o0x	A		1-{[1-(4-amino-1,3,5-triazin-2-yl)-2-methyl-1h-benzimidazol-6-yl]ethynyl}cyclohexanol	Human	Show
	PAK4	STE20	STE	2q0n	A	A	-	Human	Show
	PAK4	STE20	STE	5bms	A		n~2~-[(7-chloro-1h-benzimidazol-6-yl)methyl]-n~4~-(5-cyclopropyl-1h-pyrazol-3-yl)pyrimidine-2,4-diamine	Human	Show
	PAK4	STE20	STE	4o0y	A		4-[1-(4-amino-1,3,5-triazin-2-yl)-2-(ethylamino)-1h-benzimidazol-6-yl]-2-methylbut-3-yn-2-ol	Human	Show
	PAK4	STE20	STE	7cmb	A		1-(2-azanylpyrimidin-4-yl)-6-[2-(1-oxidanylcyclohexyl)ethynyl]indole-3-carboxamide	Human	Show
	PAK4	STE20	STE	4jdj	A	A	-	Human	Show
	PAK4	STE20	STE	5xva	A		[6-chloranyl-4-[(5-methyl-1h-pyrazol-3-yl)amino]quinazolin-2-yl]-[(3r)-3-methylpiperazin-1-yl]methanone	Human	Show
	PAK4	STE20	STE	4xbu	A		-	Human	Show
	PAK4	STE20	STE	4fie	A		phosphoaminophosphonic acid-adenylate ester	Human	Show
	PAK4	STE20	STE	4fij	A		-	Human	Show
	PAK4	STE20	STE	5upk	B		phosphoaminophosphonic acid-adenylate ester	Human	Show
	PAK4	STE20	STE	4jdk	A	A	-	Human	Show
	PAK4	STE20	STE	4jdk	A	B	-	Human	Show
	PAK4	STE20	STE	4fif	A	B	phosphoaminophosphonic acid-adenylate ester	Human	Show
	PAK4	STE20	STE	5zjw	A	A	(3z)-n-[(1s)-2-hydroxy-1-phenylethyl]-3-[(1h-imidazol-2-yl)(phenyl)methylidene]-2-oxo-2,3-dihydro-1h-indole-5-carboxamide	Human	Show
	PAK4	STE20	STE	4fif	B	B	phosphoaminophosphonic acid-adenylate ester	Human	Show
	PAK4	STE20	STE	6wlx	A	B	-	Human	Show
	PAK4	STE20	STE	7s47	A	A	phosphoaminophosphonic acid-adenylate ester	Human	Show
	PAK4	STE20	STE	4app	A	B	n-[6,6-dimethyl-5-[(2s)-4-methyl-2-(phenylmethyl)piperazin-1-yl]carbonyl-2,4-dihydropyrrolo[3,4-c]pyrazol-3-yl]-3-phenoxy-benzamide	Human	Show
	PAK4	STE20	STE	2cdz	A	A	n2-[(1r,2s)-2-aminocyclohexyl]-n6-(3-chlorophenyl)-9-ethyl-9h-purine-2,6-diamine	Human	Show
	PAK4	STE20	STE	4fie	B		phosphoaminophosphonic acid-adenylate ester	Human	Show
	PAK4	STE20	STE	7cp3	A		[(3r)-3-azanylpiperidin-1-yl]-[1-(2-azanylpyrimidin-4-yl)-6-[2-(1-oxidanylcyclohexyl)ethynyl]indol-3-yl]methanone	Human	Show
	PAK4	STE20	STE	4jdj	A	B	-	Human	Show
	PAK4	STE20	STE	4o0v	A		1-({1-(2-aminopyrimidin-4-yl)-2-[(2-methoxyethyl)amino]-1h-benzimidazol-6-yl}ethynyl)cyclohexanol	Human	Show
	PAK4	STE20	STE	2q0n	A	B	-	Human	Show
	PAK4	STE20	STE	8ahg	A	B	~{n}-methyl-3-propan-2-yl-1~{h}-pyrazolo[3,4-c]pyridine-4-carboxamide	Human	Show
	PAK4	STE20	STE	5i0b	A		6-bromo-2-[1-methyl-3-(propan-2-yl)-1h-pyrazol-4-yl]-1h-imidazo[4,5-b]pyridine	Human	Show
	PAK4	STE20	STE	8ahi	A		~{n}-methyl-1,3-benzothiazole-6-carboxamide	Human	Show
	PAK4	STE20	STE	4jdi	A	B	phosphoaminophosphonic acid-adenylate ester	Human	Show
	PAK4	STE20	STE	4fii	A	B	-	Human	Show
	PAK4	STE20	STE	6wly	A	B	-	Human	Show
	PAK4	STE20	STE	4app	A	A	n-[6,6-dimethyl-5-[(2s)-4-methyl-2-(phenylmethyl)piperazin-1-yl]carbonyl-2,4-dihydropyrrolo[3,4-c]pyrazol-3-yl]-3-phenoxy-benzamide	Human	Show
	PAK4	STE20	STE	4fii	A	A	-	Human	Show
	PAK4	STE20	STE	6wly	A	A	-	Human	Show
	PAK4	STE20	STE	5vee	A		6-(2,4-dichlorophenyl)-8-ethyl-2-{[3-fluoro-4-(piperazin-1-yl)phenyl]amino}pyrido[2,3-d]pyrimidin-7(8h)-one	Human	Show
	PAK4	STE20	STE	8ahg	A	A	~{n}-methyl-3-propan-2-yl-1~{h}-pyrazolo[3,4-c]pyridine-4-carboxamide	Human	Show
	PAK4	STE20	STE	5vef	A	B	5-(1,4-diazepan-1-sulfonyl)isoquinoline	Human	Show
	PAK4	STE20	STE	4jdh	A	B	-	Human	Show
	PAK4	STE20	STE	2bva	A		-	Human	Show
	PAK4	STE20	STE	5upl	A		-	Human	Show
	PAK4	STE20	STE	2bva	B		-	Human	Show
	PAK4	STE20	STE	5xvf	A		2-(4-azanylpiperidin-1-yl)-6-chloranyl-n-(1-methylimidazol-4-yl)quinazolin-4-amine	Human	Show
	PAK4	STE20	STE	4fig	B		phosphoaminophosphonic acid-adenylate ester	Human	Show
	PAK4	STE20	STE	5zjw	A	B	(3z)-n-[(1s)-2-hydroxy-1-phenylethyl]-3-[(1h-imidazol-2-yl)(phenyl)methylidene]-2-oxo-2,3-dihydro-1h-indole-5-carboxamide	Human	Show
	PAK4	STE20	STE	6wly	A	C	-	Human	Show
	PAK4	STE20	STE	2j0i	A	B	-	Human	Show
	PAK4	STE20	STE	4fih	A	A	-	Human	Show
	PAK4	STE20	STE	5xvg	A		[6-chloranyl-4-[(5-cyclopropyl-1h-pyrazol-3-yl)amino]quinazolin-2-yl]-[(3r)-3-methylpiperazin-1-yl]methanone	Human	Show
	PAK4	STE20	STE	2x4z	A		pf-3758309	Human	Show
	PAK4	STE20	STE	4xbr	A		adenosine-5'-triphosphate	Human	Show
	PAK4	STE20	STE	6wlx	A	A	-	Human	Show
	PAK4	STE20	STE	5vef	A	A	5-(1,4-diazepan-1-sulfonyl)isoquinoline	Human	Show
	PAK4	STE20	STE	7cp4	A		[1-(2-azanylpyrimidin-4-yl)-6-[2-(1-oxidanylcyclohexyl)ethynyl]indol-3-yl]-[(3s)-3-methylpiperazin-1-yl]methanone	Human	Show
	PAK4	STE20	STE	5ved	A		staurosporine	Human	Show
	PAK4	STE20	STE	8ahh	A	B	5-cyano-~{n}-methyl-pyrazolo[1,5-a]pyridine-3-carboxamide	Human	Show
	PAK4	STE20	STE	4njd	A	B	n-(1h-indazol-5-yl)-n'-[2-(1h-indol-3-yl)ethyl]-6-methoxy-1,3,5-triazine-2,4-diamine	Human	Show
	PAK4	STE20	STE	4jdi	A	A	phosphoaminophosphonic acid-adenylate ester	Human	Show
	PAK4	STE20	STE	4fif	A	A	phosphoaminophosphonic acid-adenylate ester	Human	Show
	PAK4	STE20	STE	7s47	A	B	phosphoaminophosphonic acid-adenylate ester	Human	Show
	PAK4	STE20	STE	4fih	A	B	-	Human	Show
	PAK4	STE20	STE	7s46	A		phosphoaminophosphonic acid-adenylate ester	Human	Show
	PAK4	STE20	STE	8ahh	A	A	5-cyano-~{n}-methyl-pyrazolo[1,5-a]pyridine-3-carboxamide	Human	Show
	PAK4	STE20	STE	2j0i	A	A	-	Human	Show
	PAK4	STE20	STE	4fif	B	A	phosphoaminophosphonic acid-adenylate ester	Human	Show

Division of Medicinal Chemistry - Vrije Universiteit Amsterdam