Serine/threonine-protein kinase mTOR
Kinase structure
Kinase:MTOR (FRAP)
Family:PIKK
Group:Atypical
Species:HUMAN
IUPHAR/BPS ID:2109
PDB:9F44
sc-PDB:
KIDFamMap:Search
Release date:2024-08-14
PubMed: 39141345
Chain:A
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The orthosteric binding pocket
Structural information
DFG conformation:in
αC-helix conformation:in
G-rich loop angle (distance):60.6° (18.1Å)
G-rich loop rotation:66.8°
Quality Score:9.6
Resolution:3.68 Å
Missing Residues:0
Missing Atoms:0

Allosteric Ligand
Allosteric ligand:IHP
2D structure of the allostericligand
Pocket alignment
Uniprot sequence:LQVITSKQRPRKLFLLKGHDLRQDERVMQLFGLSIQRYAVISGLIGWVPCDTLHALIRDVGYI--LGLGDRHPSNLMLHIDFGDC
Sequence structure:LQVITSKQRPRKLFLLKGHDLRQDERVMQLFGLSIQRYAVISGLIGWVPCDTLHALIRDVGYI__LGLGDRHPSNLMLHIDFGDC