Checkpoint kinase 1
Kinase structure
Kinase:CHEK1 (CHK1)
Family:CAMKL
Group:CAMK
Species:HUMAN
IUPHAR/BPS ID:1987
PDB:3F9N
sc-PDB:
KIDFamMap:Search
Release date:2009-01-20
PubMed: 19155174
Chain:A
(Alternate) Model:A
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The orthosteric binding pocket


More entries for 3F9N
3F9NAlternative model: BChain: A


Structural information
DFG conformation:in
αC-helix conformation:in
G-rich loop angle (distance):-
G-rich loop rotation:-
Quality Score:6.4
Resolution:1.9 Å
Missing Residues:4
Missing Atoms:0
Ligand binding mode
Waters
Cluster
I3
I4
I5
I6
I11
Ligand
No
No
No
No
No
Protein
No
Yes
Yes
No
Yes

Allosteric Ligand
Allosteric ligand:38M
2D structure of the allostericligand
Pocket alignment
Uniprot sequence:QTLGEGAYGEVQLVAVKIVNIKKEICINKMLNENVVKFYGHYLFLEYCSGGELFDRIEPYLHGIGITHRDIKPENLLLISDFGLA
Sequence structure:QTLG____GEVQLVAVKIVNIKKEICINKMLNENVVKFYGHYLFLEYCSGGELFDRIEPYLHGIGITHRDIKPENLLLISDFGLA