PDB-code
| Kinase structure | |
| Kinase: | TGFBR1 (TGFbR1) |
| Family: | STKR |
| Group: | TKL |
| Species: | HUMAN |
| IUPHAR/BPS ID: | 1788 |
| PDB: | 4X2N |
| sc-PDB: | |
| KIDFamMap: | Search |
| Release date: | 2014-12-24 |
| PubMed: | 25437144 |
| Chain: | A |
| (Alternate) Model: | B |
| More entries for 4X2N | |||||
| 4X2N | Alternative model: | A | Chain: | A | |
| Structural information | |
| DFG conformation: | in |
| αC-helix conformation: | in |
| G-rich loop angle (distance): | 53.6° (16.1Å) |
| G-rich loop rotation: | 53° |
| Quality Score: | 8 |
| Resolution: | 1.8 Å |
| Missing Residues: | 0 |
| Missing Atoms: | 0 |
| Ligand binding mode | ||||
| Waters | ||||
| Cluster I1 I2 I3 I5 I11 | Ligand No No No No No | Protein Yes Yes Yes Yes No | ||
| Pocket alignment | |
| Uniprot sequence: | ESIGKGRFGEVWRVAVKIFSWFREAEIYQTVMENILGFIAAWLVSDYHEHGSLFDYLNRTQGKPAIAHRDLKSKNILVIADLGLA |
| Sequence structure: | ESIGKGRFGEVWRVAVKIFSWFREAEIYQTVMENILGFIAAWLVSDYHEHGSLFDYLNRTQGKPAIAHRDLKSKNILVIADLGLA |
