PDB-code
Search results (75 entries covering 34 PDB structures)
| # | Kinase | Family | Group | PDB | Chain | (Alternate) Model | Orthosteric ligand | Organism | Details | File |
|---|---|---|---|---|---|---|---|---|---|---|
 | TGFBR1 (TGFbR1) | STKR | TKL | 4x2j | A | B | 4-[(3-aminophenyl)amino]pyrido[2,3-d]pyrimidin-5(8h)-one | Human | Show |  |
| TGFBR1 (TGFbR1) | STKR | TKL | 2x7o | E | (3z)-n-ethyl-n-methyl-2-oxo-3-(phenyl{[4-(piperidin-1-ylmethyl)phenyl]amino}methylidene)-2,3-dihydro-1h-indole-6-carboxamide | Human | Show | | |
| TGFBR1 (TGFbR1) | STKR | TKL | 2x7o | C | (3z)-n-ethyl-n-methyl-2-oxo-3-(phenyl{[4-(piperidin-1-ylmethyl)phenyl]amino}methylidene)-2,3-dihydro-1h-indole-6-carboxamide | Human | Show | | |
| TGFBR1 (TGFbR1) | STKR | TKL | 3tzm | A | A | 4-[5-(1,3-benzodioxol-5-yl)-4-(pyridin-2-yl)-1h-imidazol-2-yl]benzamide | Human | Show | |
| TGFBR1 (TGFbR1) | STKR | TKL | 4x2j | A | A | 4-[(3-aminophenyl)amino]pyrido[2,3-d]pyrimidin-5(8h)-one | Human | Show | |
| TGFBR1 (TGFbR1) | STKR | TKL | 3tzm | A | B | 4-[5-(1,3-benzodioxol-5-yl)-4-(pyridin-2-yl)-1h-imidazol-2-yl]benzamide | Human | Show | |
| TGFBR1 (TGFbR1) | STKR | TKL | 4x2g | A | B | 4-[(4-aminophenyl)amino]pyrido[2,3-d]pyrimidin-5(6h)-one | Human | Show | |
| TGFBR1 (TGFbR1) | STKR | TKL | 5e8u | A | - | Human | Show | | |
| TGFBR1 (TGFbR1) | STKR | TKL | 3kcf | B | 4-[3-(methoxymethyl)phenyl]-1,2-dimethyl-5-quinoxalin-6-yl-1,2-dihydro-3h-pyrazol-3-one | Human | Show | | |
| TGFBR1 (TGFbR1) | STKR | TKL | 5e8s | A | B | - | Human | Show | |
| TGFBR1 (TGFbR1) | STKR | TKL | 5e8t | A | A | - | Human | Show | |
| TGFBR1 (TGFbR1) | STKR | TKL | 5qu0 | A | A | 6-[4-(3-chloro-4-fluorophenyl)-1-(2-hydroxyethyl)-1h-imidazol-5-yl]imidazo[1,2-b]pyridazine-3-carbonitrile | Human | Show | |
| TGFBR1 (TGFbR1) | STKR | TKL | 3faa | E | n-[4-(5-fluoro-6-methylpyridin-2-yl)-5-quinoxalin-6-yl-1h-imidazol-2-yl]acetamide | Human | Show | | |
| TGFBR1 (TGFbR1) | STKR | TKL | 5e8w | A | A | staurosporine | Human | Show | |
| TGFBR1 (TGFbR1) | STKR | TKL | 5e90 | A | B | 3-amino-6-[4-(2-hydroxyethyl)phenyl]-n-[4-(morpholin-4-yl)pyridin-3-yl]pyrazine-2-carboxamide | Human | Show | |
| TGFBR1 (TGFbR1) | STKR | TKL | 1b6c | D | - | Human | Show | | |
| TGFBR1 (TGFbR1) | STKR | TKL | 1rw8 | A | 3-(4-fluorophenyl)-2-(6-methylpyridin-2-yl)-5,6-dihydro-4h-pyrrolo[1,2-b]pyrazole | Human | Show | | |
| TGFBR1 (TGFbR1) | STKR | TKL | 3kcf | C | 4-[3-(methoxymethyl)phenyl]-1,2-dimethyl-5-quinoxalin-6-yl-1,2-dihydro-3h-pyrazol-3-one | Human | Show | | |
| TGFBR1 (TGFbR1) | STKR | TKL | 6b8y | A | A | n-(3-fluoropyridin-4-yl)-2-[6-(trifluoromethyl)pyridin-2-yl]-7h-pyrrolo[2,3-d]pyrimidin-4-amine | Human | Show | |
| TGFBR1 (TGFbR1) | STKR | TKL | 5fri | A | B | n-[4-[(6-chloro-[1,3]dioxolo[4,5-b]pyridin-7-yl)amino]-2-pyridyl]cyclopropanecarboxamide | Human | Show | |
| TGFBR1 (TGFbR1) | STKR | TKL | 5e8z | A | A | 3-amino-6-[4-(2-hydroxyethyl)phenyl]-n-[4-(morpholin-4-yl)pyridin-3-yl]pyrazine-2-carboxamide | Human | Show | |
| TGFBR1 (TGFbR1) | STKR | TKL | 5qu0 | A | B | 6-[4-(3-chloro-4-fluorophenyl)-1-(2-hydroxyethyl)-1h-imidazol-5-yl]imidazo[1,2-b]pyridazine-3-carbonitrile | Human | Show | |
| TGFBR1 (TGFbR1) | STKR | TKL | 5e90 | A | A | 3-amino-6-[4-(2-hydroxyethyl)phenyl]-n-[4-(morpholin-4-yl)pyridin-3-yl]pyrazine-2-carboxamide | Human | Show | |
| TGFBR1 (TGFbR1) | STKR | TKL | 3faa | C | n-[4-(5-fluoro-6-methylpyridin-2-yl)-5-quinoxalin-6-yl-1h-imidazol-2-yl]acetamide | Human | Show | | |
| TGFBR1 (TGFbR1) | STKR | TKL | 2x7o | A | (3z)-n-ethyl-n-methyl-2-oxo-3-(phenyl{[4-(piperidin-1-ylmethyl)phenyl]amino}methylidene)-2,3-dihydro-1h-indole-6-carboxamide | Human | Show | | |
| TGFBR1 (TGFbR1) | STKR | TKL | 5qik | A | A | n-{4-[3-(6-fluoropyridin-3-yl)-4-oxo-4,5,6,7-tetrahydro-1h-pyrrolo[3,2-c]pyridin-2-yl]pyridin-2-yl}acetamide | Human | Show | |
| TGFBR1 (TGFbR1) | STKR | TKL | 4x2k | A | A | 4-[(3-aminophenyl)amino]pyrido[2,3-d]pyrimidin-5(6h)-one | Human | Show | |
| TGFBR1 (TGFbR1) | STKR | TKL | 5qim | A | A | n-{4-[3-(5-methoxypyridin-2-yl)-1h-pyrrolo[3,2-b]pyridin-2-yl]pyridin-2-yl}acetamide | Human | Show | |
| TGFBR1 (TGFbR1) | STKR | TKL | 3kcf | D | 4-[3-(methoxymethyl)phenyl]-1,2-dimethyl-5-quinoxalin-6-yl-1,2-dihydro-3h-pyrazol-3-one | Human | Show | | |
| TGFBR1 (TGFbR1) | STKR | TKL | 3faa | D | n-[4-(5-fluoro-6-methylpyridin-2-yl)-5-quinoxalin-6-yl-1h-imidazol-2-yl]acetamide | Human | Show | | |
| TGFBR1 (TGFbR1) | STKR | TKL | 4x2g | A | A | 4-[(4-aminophenyl)amino]pyrido[2,3-d]pyrimidin-5(6h)-one | Human | Show | |
| TGFBR1 (TGFbR1) | STKR | TKL | 5e8x | A | B | staurosporine | Human | Show | |
| TGFBR1 (TGFbR1) | STKR | TKL | 5qil | A | A | n-{4-[3-(6-methoxypyridin-3-yl)-1h-pyrrolo[3,2-b]pyridin-2-yl]pyridin-2-yl}acetamide | Human | Show | |
| TGFBR1 (TGFbR1) | STKR | TKL | 1ias | D | - | Human | Show | | |
| TGFBR1 (TGFbR1) | STKR | TKL | 1b6c | F | - | Human | Show | | |
| TGFBR1 (TGFbR1) | STKR | TKL | 3faa | B | n-[4-(5-fluoro-6-methylpyridin-2-yl)-5-quinoxalin-6-yl-1h-imidazol-2-yl]acetamide | Human | Show | | |
| TGFBR1 (TGFbR1) | STKR | TKL | 6b8y | A | B | n-(3-fluoropyridin-4-yl)-2-[6-(trifluoromethyl)pyridin-2-yl]-7h-pyrrolo[2,3-d]pyrimidin-4-amine | Human | Show | |
| TGFBR1 (TGFbR1) | STKR | TKL | 3kcf | E | 4-[3-(methoxymethyl)phenyl]-1,2-dimethyl-5-quinoxalin-6-yl-1,2-dihydro-3h-pyrazol-3-one | Human | Show | | |
| TGFBR1 (TGFbR1) | STKR | TKL | 5qik | A | B | n-{4-[3-(6-fluoropyridin-3-yl)-4-oxo-4,5,6,7-tetrahydro-1h-pyrrolo[3,2-c]pyridin-2-yl]pyridin-2-yl}acetamide | Human | Show | |
| TGFBR1 (TGFbR1) | STKR | TKL | 5qim | A | B | n-{4-[3-(5-methoxypyridin-2-yl)-1h-pyrrolo[3,2-b]pyridin-2-yl]pyridin-2-yl}acetamide | Human | Show | |
| TGFBR1 (TGFbR1) | STKR | TKL | 1ias | A | - | Human | Show | | |
| TGFBR1 (TGFbR1) | STKR | TKL | 5fri | A | A | n-[4-[(6-chloro-[1,3]dioxolo[4,5-b]pyridin-7-yl)amino]-2-pyridyl]cyclopropanecarboxamide | Human | Show | |
| TGFBR1 (TGFbR1) | STKR | TKL | 2x7o | D | (3z)-n-ethyl-n-methyl-2-oxo-3-(phenyl{[4-(piperidin-1-ylmethyl)phenyl]amino}methylidene)-2,3-dihydro-1h-indole-6-carboxamide | Human | Show | | |
| TGFBR1 (TGFbR1) | STKR | TKL | 5qtz | A | A | 6-[1-(2,2-difluoroethyl)-4-(6-methylpyridin-2-yl)-1h-imidazol-5-yl]imidazo[1,2-a]pyridine | Human | Show | |
| TGFBR1 (TGFbR1) | STKR | TKL | 4x2f | A | B | 4-amino-8-(4-aminophenyl)pyrido[2,3-d]pyrimidin-5(8h)-one | Human | Show | |
| TGFBR1 (TGFbR1) | STKR | TKL | 1vjy | A | 2-[5-(6-methylpyridin-2-yl)-2,3-dihydro-1h-pyrazol-4-yl]-1,5-naphthyridine | Human | Show | | |
| TGFBR1 (TGFbR1) | STKR | TKL | 5e8s | A | A | - | Human | Show | |
| TGFBR1 (TGFbR1) | STKR | TKL | 5usq | A | A | n-[2-(5-chloro-2-fluorophenyl)pyridin-4-yl]-2-[(piperidin-4-yl)methyl]-2h-pyrazolo[4,3-b]pyridin-7-amine | Human | Show | |
| TGFBR1 (TGFbR1) | STKR | TKL | 5qil | A | B | n-{4-[3-(6-methoxypyridin-3-yl)-1h-pyrrolo[3,2-b]pyridin-2-yl]pyridin-2-yl}acetamide | Human | Show | |
| TGFBR1 (TGFbR1) | STKR | TKL | 4x0m | A | B | 4-aminopyrido[2,3-d]pyrimidin-5(8h)-one | Human | Show | |
| TGFBR1 (TGFbR1) | STKR | TKL | 4x2n | A | B | - | Human | Show | |
| TGFBR1 (TGFbR1) | STKR | TKL | 5e8z | A | B | 3-amino-6-[4-(2-hydroxyethyl)phenyl]-n-[4-(morpholin-4-yl)pyridin-3-yl]pyrazine-2-carboxamide | Human | Show | |
| TGFBR1 (TGFbR1) | STKR | TKL | 1py5 | A | 4-(3-pyridin-2-yl-1h-pyrazol-4-yl)quinoline | Human | Show | | |
| TGFBR1 (TGFbR1) | STKR | TKL | 3hmm | A | 2-(6-methylpyridin-2-yl)-n-pyridin-4-ylquinazolin-4-amine | Human | Show | | |
| TGFBR1 (TGFbR1) | STKR | TKL | 1ias | C | - | Human | Show | | |
| TGFBR1 (TGFbR1) | STKR | TKL | 5e8t | A | B | - | Human | Show | |
| TGFBR1 (TGFbR1) | STKR | TKL | 2wot | A | B | 4-[(5,6-dimethyl-2,2'-bipyridin-3-yl)oxy]-n-(3,4,5-trimethoxyphenyl)pyridin-2-amine | Human | Show | |
| TGFBR1 (TGFbR1) | STKR | TKL | 5usq | A | B | n-[2-(5-chloro-2-fluorophenyl)pyridin-4-yl]-2-[(piperidin-4-yl)methyl]-2h-pyrazolo[4,3-b]pyridin-7-amine | Human | Show | |
| TGFBR1 (TGFbR1) | STKR | TKL | 1ias | B | - | Human | Show | | |
| TGFBR1 (TGFbR1) | STKR | TKL | 3gxl | A | n-1h-indazol-5-yl-2-(6-methylpyridin-2-yl)quinazolin-4-amine | Human | Show | | |
| TGFBR1 (TGFbR1) | STKR | TKL | 4x2f | A | A | 4-amino-8-(4-aminophenyl)pyrido[2,3-d]pyrimidin-5(8h)-one | Human | Show | |
| TGFBR1 (TGFbR1) | STKR | TKL | 2wou | A | 4-({4-[(2,6-dimethylpyridin-3-yl)oxy]pyridin-2-yl}amino)benzenesulfonamide | Human | Show | | |
| TGFBR1 (TGFbR1) | STKR | TKL | 1ias | E | - | Human | Show | | |
| TGFBR1 (TGFbR1) | STKR | TKL | 4x2n | A | A | - | Human | Show | |
| TGFBR1 (TGFbR1) | STKR | TKL | 5e8w | A | B | staurosporine | Human | Show | |
| TGFBR1 (TGFbR1) | STKR | TKL | 3kcf | A | 4-[3-(methoxymethyl)phenyl]-1,2-dimethyl-5-quinoxalin-6-yl-1,2-dihydro-3h-pyrazol-3-one | Human | Show | | |
| TGFBR1 (TGFbR1) | STKR | TKL | 5qtz | A | B | 6-[1-(2,2-difluoroethyl)-4-(6-methylpyridin-2-yl)-1h-imidazol-5-yl]imidazo[1,2-a]pyridine | Human | Show | |
| TGFBR1 (TGFbR1) | STKR | TKL | 1b6c | B | - | Human | Show | | |
| TGFBR1 (TGFbR1) | STKR | TKL | 4x0m | A | A | 4-aminopyrido[2,3-d]pyrimidin-5(8h)-one | Human | Show | |
| TGFBR1 (TGFbR1) | STKR | TKL | 3faa | A | n-[4-(5-fluoro-6-methylpyridin-2-yl)-5-quinoxalin-6-yl-1h-imidazol-2-yl]acetamide | Human | Show | | |
| TGFBR1 (TGFbR1) | STKR | TKL | 2x7o | B | (3z)-n-ethyl-n-methyl-2-oxo-3-(phenyl{[4-(piperidin-1-ylmethyl)phenyl]amino}methylidene)-2,3-dihydro-1h-indole-6-carboxamide | Human | Show | | |
| TGFBR1 (TGFbR1) | STKR | TKL | 4x2k | A | B | 4-[(3-aminophenyl)amino]pyrido[2,3-d]pyrimidin-5(6h)-one | Human | Show | |
| TGFBR1 (TGFbR1) | STKR | TKL | 2wot | A | A | 4-[(5,6-dimethyl-2,2'-bipyridin-3-yl)oxy]-n-(3,4,5-trimethoxyphenyl)pyridin-2-amine | Human | Show | |
| TGFBR1 (TGFbR1) | STKR | TKL | 5e8x | A | A | staurosporine | Human | Show | |
| TGFBR1 (TGFbR1) | STKR | TKL | 1b6c | H | - | Human | Show | |
