Cyclin-dependent kinase 9
Kinase structure
Kinase:CDK9
Family:CDK
Group:CMGC
Species:HUMAN
IUPHAR/BPS ID:1981
PDB:3MI9
sc-PDB:
KIDFamMap:Search
Release date:2010-06-09
PubMed: 20535204
Chain:A
Click to open a 3D viewer
The orthosteric binding pocket
Structural information
DFG conformation:in
αC-helix conformation:in
G-rich loop angle (distance):67.6° (20.2Å)
G-rich loop rotation:71.6°
Quality Score:8
Resolution:2.1 Å
Missing Residues:0
Missing Atoms:0
Ligand binding mode
Waters
Cluster
I3
I4
I5
I6
I7
I10
I11
Ligand
No
No
No
No
No
No
No
Protein
Yes
Yes
Yes
No
Yes
Yes
Yes

Pocket alignment
Uniprot sequence:AKIGQGTFGEVFKVALKKVTALREIKILQLLKENVVNLIEIYLVFDFCE-HDLAGLLSNYIHRNKILHRDMKAANVLILADFGLA
Sequence structure:AKIGQGTFGEVFKVALKKVTALREIKILQLLKENVVNLIEIYLVFDFCE_HDLAGLLSNYIHRNKILHRDMKAANVLILADFGLA