LCK proto-oncogene, Src family tyrosine kinase
Kinase structure
Kinase:LCK
Family:Src
Group:TK
Species:HUMAN
IUPHAR/BPS ID:2053
PDB:3LCK
sc-PDB:
KIDFamMap:Search
Release date:1997-12-03
PubMed: 8945479
Chain:A
(Alternate) Model:B
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The orthosteric binding pocket


More entries for 3LCK
3LCKAlternative model: AChain: A


Structural information
DFG conformation:in
αC-helix conformation:in
G-rich loop angle (distance):66.5° (20.4Å)
G-rich loop rotation:40.6°
Quality Score:8
Resolution:1.7 Å
Missing Residues:0
Missing Atoms:0
Ligand binding mode
Waters
Cluster
I1
I3
I5
I6
I10
Ligand
No
No
No
No
No
Protein
Yes
No
Yes
No
Yes

Pocket alignment
Uniprot sequence:ERLGAGQFGEVWMVAVKSLAFLAEANLMKQLQQRLVRLYAVYIITEYMENGSLVDFLKTFIEERNYIHRDLRAANILVIADFGLA
Sequence structure:ERLGAGQFGEVWMVAVKSLAFLAEANLMKQLQQRLVRLYAVYIITEYMENGSLVDFLKTFIEERNYIHRDLRAANILVIADFGLA