PDB-code
Search results (41 entries covering 35 PDB structures)
| # | Kinase | Family | Group | PDB | Chain | (Alternate) Model | Orthosteric ligand | Organism | Details | File |
|---|---|---|---|---|---|---|---|---|---|---|
 | LCK | Src | TK | 6pdj | A | B | n-{4-[(6-methoxypyrazolo[1,5-a]pyridine-3-carbonyl)amino]-3-methylphenyl}-1-methyl-1h-indazole-3-carboxamide | Human | Show |  |
| LCK | Src | TK | 3kmm | A | 3-(2,6-dichlorophenyl)-7-({4-[2-(diethylamino)ethoxy]phenyl}amino)-1-methyl-3,4-dihydropyrimido[4,5-d]pyrimidin-2(1h)-one | Human | Show | | |
| LCK | Src | TK | 3mpm | A | B | 4-{(6r,7r)-7-amino-3-[3-(4-methylpiperazin-1-yl)phenyl]-6,7-dihydropyrazolo[1,5-a]pyrimidin-6-yl}phenol | Human | Show | |
| LCK | Src | TK | 2ofv | A | 3-(2-aminoquinazolin-6-yl)-4-methyl-n-[3-(trifluoromethyl)phenyl]benzamide | Human | Show | | |
| LCK | Src | TK | 3b2w | A | n-[5-({[2-fluoro-3-(trifluoromethyl)phenyl]amino}carbonyl)-2-methylphenyl]-4-methoxy-2-[(4-piperazin-1-ylphenyl)amino]pyrimidine-5-carboxamide | Human | Show | | |
| LCK | Src | TK | 2ofu | A | 2,6-dimethylphenyl 2-(3,5-dimethoxy-4-(3-(4-methylpiperazin-1-yl)propoxy)phenylamino)pyrimidin- 4-yl(2,4-dimethoxyphenyl)carbamate | Human | Show | | |
| LCK | Src | TK | 3byo | A | 6-(2,6-dimethylphenyl)-2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}pyrimido[5',4':5,6]pyrimido[1,2-a]benzimidazol-5(6h)-one | Human | Show | | |
| LCK | Src | TK | 3mpm | A | A | 4-{(6r,7r)-7-amino-3-[3-(4-methylpiperazin-1-yl)phenyl]-6,7-dihydropyrazolo[1,5-a]pyrimidin-6-yl}phenol | Human | Show | |
| LCK | Src | TK | 3ac4 | A | 5-[(2-amino-1,1-dimethylethyl)amino]-7-[(3,5-dimethoxyphenyl)amino][1,2,4]triazolo[4,3-c]pyrimidine-8-carboxamide | Human | Show | | |
| LCK | Src | TK | 3ac5 | A | 5-{[(1r,2s)-2-aminocyclohexyl]amino}-7-[(3,5-dimethoxyphenyl)amino]-2-(3-hydroxyphenyl)[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxamide | Human | Show | | |
| LCK | Src | TK | 1qpd | A | staurosporine | Human | Show | | |
| LCK | Src | TK | 2og8 | B | n-{2-[(n,n-diethylglycyl)amino]-5-(trifluoromethyl)phenyl}-4-methyl-3-[2-(methylamino)quinazolin-6-yl]benzamide | Human | Show | | |
| LCK | Src | TK | 1qpc | A | phosphoaminophosphonic acid-adenylate ester | Human | Show | | |
| LCK | Src | TK | 3bym | A | n-phenyl-1-{4-[(3,4,5-trimethoxyphenyl)amino]-1,3,5-triazin-2-yl}-1h-benzimidazol-2-amine | Human | Show | | |
| LCK | Src | TK | 2of2 | A | 2,3-diphenyl-n-(2-piperazin-1-ylethyl)furo[2,3-b]pyridin-4-amine | Human | Show | | |
| LCK | Src | TK | 4c3f | A | B | n-phenyl-4-(5-phenyl-1h-pyrazol-4-yl)pyrimidin-2-amine | Human | Show | |
| LCK | Src | TK | 2zm4 | A | n-(2-chloro-6-methylphenyl)-8-[(3s)-3-methylpiperazin-1-yl]imidazo[1,5-a]quinoxalin-4-amine | Human | Show | | |
| LCK | Src | TK | 3ad5 | A | 4-[4-(benzyloxy)phenyl]-5-{[2-(4-chlorophenyl)-2-oxoethyl]sulfanyl}-2,4-dihydro-3h-1,2,4-triazol-3-one | Human | Show | | |
| LCK | Src | TK | 2og8 | A | n-{2-[(n,n-diethylglycyl)amino]-5-(trifluoromethyl)phenyl}-4-methyl-3-[2-(methylamino)quinazolin-6-yl]benzamide | Human | Show | | |
| LCK | Src | TK | 2pl0 | A | 4-(4-methyl-piperazin-1-ylmethyl)-n-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-benzamide | Human | Show | | |
| LCK | Src | TK | 3lck | A | A | - | Human | Show | |
| LCK | Src | TK | 2zm1 | A | n-(2-chlorophenyl)-5-phenylimidazo[1,5-a]pyrazin-8-amine | Human | Show | | |
| LCK | Src | TK | 3ac8 | A | 7-[(2-amino-2-methylpropyl)amino]-5-cyclopropyl-2-[(3,5-dimethoxyphenyl)amino]pyrazolo[1,5-a]pyrimidine-3-carboxamide | Human | Show | | |
| LCK | Src | TK | 4c3f | A | A | n-phenyl-4-(5-phenyl-1h-pyrazol-4-yl)pyrimidin-2-amine | Human | Show | |
| LCK | Src | TK | 3acj | A | 7-(3,4-dimethoxyphenyl)-5-(ethylsulfanyl)imidazo[1,2-c]pyrimidine | Human | Show | | |
| LCK | Src | TK | 3byu | A | 2-methyl-n-{4-methyl-3-[(2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}pyrimidin-5-yl)carbamoyl]phenyl}-3-(trifluoromethyl)benzamide | Human | Show | | |
| LCK | Src | TK | 2zyb | A | n-(2,6-dimethylphenyl)-5-phenylimidazo[1,5-a]pyrazin-8-amine | Human | Show | | |
| LCK | Src | TK | 1qpj | A | staurosporine | Human | Show | | |
| LCK | Src | TK | 3ac1 | A | 5-{[(1r,2s)-2-aminocyclohexyl]amino}-3-[(3,5-dimethoxyphenyl)amino]pyrazine-2-carboxamide | Human | Show | | |
| LCK | Src | TK | 3ac3 | A | 2-[(3,5-dimethoxyphenyl)amino]-5-ethyl-7-[(2r)-2-(hydroxymethyl)pyrrolidin-1-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide | Human | Show | | |
| LCK | Src | TK | 2ofv | B | 3-(2-aminoquinazolin-6-yl)-4-methyl-n-[3-(trifluoromethyl)phenyl]benzamide | Human | Show | | |
| LCK | Src | TK | 3ad4 | A | (4-chlorophenyl)(5-methoxy-1-benzofuran-2-yl)methanone | Human | Show | | |
| LCK | Src | TK | 3bys | A | 4-methyl-n~3~-(2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}pyrimidin-5-yl)-n~1~-[3-(trifluoromethyl)phenyl]benzene-1,3-dicarboxamide | Human | Show | | |
| LCK | Src | TK | 3kxz | A | 3-[7-[(3-hydroxyphenyl)amino]pyrazolo[1,5-a]pyrimidin-2-yl]-n-(1-hydroxy-2,2,6,6-tetramethyl-piperidin-4-yl)benzamide | Human | Show | | |
| LCK | Src | TK | 3ad6 | A | 7-[(cyclopropylmethyl)amino]-2-[(4-methoxyphenyl)amino]-5-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide | Human | Show | | |
| LCK | Src | TK | 3ac2 | A | 7-[(2-amino-2-methylpropyl)amino]-2-[(3,5-dimethoxyphenyl)amino]-5-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide | Human | Show | | |
| LCK | Src | TK | 3lck | A | B | - | Human | Show | |
| LCK | Src | TK | 1qpe | A | 1-tert-butyl-3-(4-chloro-phenyl)-1h-pyrazolo[3,4-d]pyrimidin-4-ylamine | Human | Show | | |
| LCK | Src | TK | 6pdj | A | A | n-{4-[(6-methoxypyrazolo[1,5-a]pyridine-3-carbonyl)amino]-3-methylphenyl}-1-methyl-1h-indazole-3-carboxamide | Human | Show | |
| LCK | Src | TK | 2of4 | A | 5,6-diphenyl-n-(2-piperazin-1-ylethyl)furo[2,3-d]pyrimidin-4-amine | Human | Show | | |
| LCK | Src | TK | 3ack | A | 6-(5-methoxy-1-methyl-1h-indol-3-yl)-5h-pyrrolo[2,3-b]pyrazine | Human | Show | |
