Microtubule affinity regulating kinase 2
Kinase structure
Kinase:MARK2
Family:CAMKL
Group:CAMK
Species:HUMAN
IUPHAR/BPS ID:2098
PDB:3IEC
sc-PDB:
KIDFamMap:Search
Release date:2009-12-08
PubMed: 19966800
Chain:B
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The orthosteric binding pocket


More entries for 3IEC
3IECChain: A
3IECChain: C
3IECChain: D


Structural information
DFG conformation:in
αC-helix conformation:in
G-rich loop angle (distance):63.6° (18.5Å)
G-rich loop rotation:60.3°
Quality Score:7.2
Resolution:2.2 Å
Missing Residues:2
Missing Atoms:0
Ligand binding mode
Waters
Cluster
I1
I4
I11
Ligand
No
No
No
Protein
Yes
Yes
No

Pocket alignment
Uniprot sequence:KTIGKGNFAKVKLVAVKIIKLFREVRIMKVLNPNIVKLFEVYLVMEYASGGEVFDYLVAYCHQKFIVHRDLKAENLLLIADFGFS
Sequence structure:KTIGKG__AKVKLVAVKIIKLFREVRIMKVLNPNIVKLFEVYLVMEYASGGEVFDYLVAYCHQKFIVHRDLKAENLLLIADFGFS