Dual specificity tyrosine phosphorylation regulated kinase 2
Kinase structure
Kinase:DYRK2
Family:DYRK
Group:CMGC
Species:HUMAN
IUPHAR/BPS ID:2011
PDB:3K2L
sc-PDB:
KIDFamMap:Search
Release date:2009-10-13
PubMed: 23665168
Chain:A
(Alternate) Model:B
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The orthosteric binding pocket


More entries for 3K2L
3K2LAlternative model: AChain: A


Structural information
DFG conformation:in
αC-helix conformation:in
G-rich loop angle (distance):53.5° (16.4Å)
G-rich loop rotation:46.1°
Quality Score:7.6
Resolution:2.36 Å
Missing Residues:1
Missing Atoms:38
Ligand binding mode
Waters
Cluster
I10
I11
Ligand
No
No
Protein
Yes
Yes

Pocket alignment
Uniprot sequence:KVIGKGSFGQVVKVALKMVQAAEEIRILEHLRMNVIHMLENCMTFELLS-MNLYELIKKALHKNRIIHCDLKPENILLVIDFGSS
Sequence structure:KVIGKG_FGQVVKVALKMVQAAEEIRILEHLRMNVIHMLENCMTFELLS_MNLYELIKKALHKNRIIHCDLKPENILLVIDFGSS